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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:64.8 nTPM
HPA:64.8 nTPM
GTEx:84.9 nTPM
FANTOM5:42.8 Scaled Tags Per Million
Pig:13.1 nTPM
Mouse:102.7 nTPM
Allen mouse:8.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 64.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 60.6
2586 Male, age 75, left hemisphere 65.3
2019 Male, age 18, unknown 64.0
2411 Female, age 72, unknown 61.8
1870 Female, age 42, unknown 61.5
1827 Male, age 72, unknown 60.9
2219 Male, age 76, both hemispheres 60.8
2828 Female, age 72, unknown 60.2
1833 Male, age 53, unknown 58.5
1830 Male, age 51, unknown 57.3
2666 Male, age 74, left hemisphere 55.6
Dorsal raphe nucleus
nTPM: 63.6
2298 Female, age 72, unknown 69.9
2016 Female, age 72, unknown 64.8
1828 Male, age 53, unknown 62.6
2750 Male, age 76, both hemispheres 60.4
2047 Male, age 72, unknown 60.2
Inferior colliculus
nTPM: 58.0
1890 Male, age 53, unknown 59.9
2097 Female, age 72, unknown 59.6
1848 Female, age 42, unknown 57.4
2849 Male, age 72, unknown 55.2
Median raphe nucleus
nTPM: 59.3
2220 Male, age 76, midline 59.3
Pedunculopontine tegmental nucleus
nTPM: 58.3
1921 Female, age 85, both hemispheres 59.1
2334 Male, age 80, both hemispheres 59.0
2338 Male, age 61, both hemispheres 56.7
Periaquaductal grey, anterior
nTPM: 62.0
1795 Male, age 51, unknown 64.3
2502 Female, age 75, unknown 61.4
1947 Male, age 18, unknown 60.4
Periaquaductal grey, dorsal
nTPM: 58.6
2850 Male, age 76, both hemispheres 59.7
1840 Male, age 53, unknown 59.2
1831 Male, age 72, unknown 57.9
2464 Female, age 72, unknown 57.6
Periaquaductal grey, lateral
nTPM: 60.8
2272 Male, age 74, both hemispheres 65.5
2053 Male, age 18, unknown 58.9
2140 Male, age 76, both hemispheres 57.9
Pretectal area
nTPM: 61.3
2273 Male, age 74, both hemispheres 68.1
2007 Male, age 72, unknown 64.2
2224 Female, age 72, unknown 62.5
1816 Male, age 51, unknown 61.9
2667 Female, age 75, unknown 61.9
1817 Female, age 42, unknown 61.5
1944 Female, age 72, unknown 61.3
1815 Male, age 53, unknown 60.2
2825 Male, age 18, unknown 58.7
2316 Male, age 76, right hemisphere 57.2
2407 Male, age 75, both hemispheres 57.0
Red nucleus
nTPM: 61.4
2503 Female, age 72, unknown 64.0
1821 Female, age 72, unknown 63.7
1904 Male, age 53, unknown 63.7
1865 Male, age 51, unknown 63.3
1954 Female, age 42, unknown 62.7
2769 Male, age 72, unknown 62.7
2785 Male, age 18, unknown 61.1
2227 Male, age 72, unknown 61.0
2725 Female, age 75, unknown 60.3
2588 Male, age 74, left hemisphere 59.0
2823 Male, age 76, right hemisphere 58.4
2584 Male, age 75, left hemisphere 56.6
Substantia nigra
nTPM: 64.8
1851 Male, age 51, unknown 70.9
1916 Female, age 42, unknown 70.3
2241 Male, age 72, unknown 67.0
2699 Male, age 18, unknown 65.5
1941 Male, age 53, unknown 64.3
2590 Female, age 75, unknown 62.9
1889 Female, age 72, unknown 62.8
2409 Female, age 72, unknown 61.7
2583 Male, age 75, right hemisphere 61.6
2665 Male, age 74, both hemispheres 60.7
Superior colliculus
nTPM: 59.9
2587 Male, age 74, left hemisphere 62.0
2668 Female, age 75, unknown 61.8
1796 Male, age 53, unknown 61.7
2261 Male, age 18, unknown 61.5
2664 Male, age 75, both hemispheres 60.9
1995 Male, age 72, unknown 60.4
2087 Female, age 72, unknown 58.8
1913 Female, age 42, unknown 58.7
1895 Male, age 76, right hemisphere 57.2
1839 Male, age 51, unknown 55.9
Ventral tegmental area
nTPM: 63.5
2410 Female, age 72, unknown 68.6
1915 Female, age 42, unknown 67.0
2218 Male, age 76, both hemispheres 61.9
1942 Male, age 51, unknown 61.8
2223 Female, age 72, unknown 61.6
2021 Male, age 53, unknown 59.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 84.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 84.9
Samples: 139

Max nTPM: 159.8
Min nTPM: 48.1
Std nTPM: 17.8
Median nTPM: 81.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 159.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 133.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 133.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 130.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 129.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 125.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 119.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 117.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 114.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 112.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 111.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 110.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 110.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 108.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 107.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 107.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 106.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 106.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 105.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 104.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 103.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 103.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 102.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 99.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 99.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 98.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 98.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 96.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 96.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 95.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 95.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 95.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 94.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 94.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 93.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 93.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 92.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 92.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 92.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 91.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 91.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 90.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 90.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 89.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 89.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 88.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 87.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 87.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 87.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 87.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 87.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 86.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 85.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 85.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 85.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 85.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 85.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 85.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 85.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 84.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 84.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 84.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 83.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 83.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 82.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 82.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 82.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 82.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 81.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 81.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 81.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 80.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 80.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 80.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 80.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 80.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 79.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 79.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 79.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 79.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 79.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 78.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 78.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 78.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 78.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 78.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 78.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 78.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 78.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 78.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 78.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 77.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 77.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 76.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 75.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 75.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 74.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 73.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 73.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 73.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 73.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 73.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 72.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 72.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 72.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 72.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 72.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 71.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 71.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 71.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 70.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 70.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 70.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 70.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 70.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 69.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 69.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 68.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 68.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 68.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 68.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 67.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 67.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 66.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 66.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 66.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 66.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 66.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 66.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 65.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 62.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 61.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 60.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 60.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 58.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 55.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 54.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 54.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 48.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 42.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 42.8
FF:10158-103A5 76 years, female 42.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 13.1
Pig sample Sample description nTPM
Midbrain
nTPM: 12.7
Samples: 4

Max nTPM: 14.7
Min nTPM: 10.8
Sample A Female 13.8
Sample B Female 10.8
Sample C Male 14.7
Sample D Male 11.6
Periaqueductal gray
nTPM: 10.5
Samples: 3

Max nTPM: 12.3
Min nTPM: 9.4
Sample B Female 9.8
Sample C Male 12.3
Sample D Male 9.4
Substantia nigra
nTPM: 11.8
Samples: 4

Max nTPM: 16.1
Min nTPM: 8.7
Sample A Female 16.1
Sample B Female 9.7
Sample C Male 12.8
Sample D Male 8.7
Superior colliculi
nTPM: 13.2
Samples: 4

Max nTPM: 15.7
Min nTPM: 10.0
Sample A Female 15.7
Sample B Female 10.0
Sample C Male 15.4
Sample D Male 11.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 102.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 102.7
Samples: 4

Max nTPM: 112.7
Min nTPM: 96.2
Sample A Male 112.7
Sample B Male 98.2
Sample C Female 96.2
Sample D Female 103.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 8.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 8.2
68862156 Antisense, RP_050301_01_F06, Mouse strain C57BL/6J (56 days, male) 8.2

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