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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA046772
Most normal tissues showed moderate cytoplasmic positivity. Ganglion cells, neuronal cells, Purkinje cells, glial cells and cells in molecular layer of cerebellum were strongly stained. Strong membranous immunoreactivity was observed in endometrial glands and seminal vesicle. Bile ducts, salivary gland, lymphoid cells, hematopoietic cells and adipocytes were negative.
HPA049489
Neuronal cells, cells in molecular layer of cerebellum, intestine, hematopoietic cells and testis showed strong Cytoplasmic staining with additional nuclear and/or membranous positivity. Respiratory epithelia, Purkinje cells, glandular cells of cervix, gallbladder, myocytes, oral mucosa, decidual cells and stomach were moderately stained. Remaining normal tissues were weakly stained or negative.
The Human Protein Atlas project is funded
