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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA035516
Most normal tissues exhibited weak to moderate nuclear positivity, with additional cytoplasmic positivity in several cases. A subset of cells in seminiferus ducts displayed strong nuclear and cytoplasmic staining, and Leydig cells displayed strong nuclear staining. Parathyroid gland, bile duct cells, and a subset of lymphoid tissue were negative.
HPA035517
Most of the normal cells showed weak to moderate cytoplasmic immunoreactivity in combination with nuclear staining in several tissues. The small intestine and fractions of neuronal cells were strongly stained.
HPA061469
Moderate to strong cytoplasmic positivity was observed in cells in seminiferous ducts, glandular cells in GI and a subset of immune cells in lymphoid tissues. Remaining normal tissues were mainly negative.
The Human Protein Atlas project is funded
