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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:129.6 nTPM
HPA:129.6 nTPM
GTEx:164.1 nTPM
FANTOM5:270.8 Scaled Tags Per Million
Pig:28.2 nTPM
Mouse:108.4 nTPM
Allen mouse:4.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 129.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 114.8
1870 Female, age 42, unknown 130.1
2411 Female, age 72, unknown 124.1
1830 Male, age 51, unknown 122.6
2828 Female, age 72, unknown 120.6
2019 Male, age 18, unknown 120.1
1833 Male, age 53, unknown 120.0
2666 Male, age 74, left hemisphere 107.8
1827 Male, age 72, unknown 106.3
2219 Male, age 76, both hemispheres 102.7
2586 Male, age 75, left hemisphere 94.0
Dorsal raphe nucleus
nTPM: 123.4
2750 Male, age 76, both hemispheres 126.8
2016 Female, age 72, unknown 126.6
1828 Male, age 53, unknown 125.1
2298 Female, age 72, unknown 122.6
2047 Male, age 72, unknown 115.9
Inferior colliculus
nTPM: 113.5
1848 Female, age 42, unknown 117.7
2097 Female, age 72, unknown 114.6
1890 Male, age 53, unknown 111.5
2849 Male, age 72, unknown 110.1
Median raphe nucleus
nTPM: 118.9
2220 Male, age 76, midline 118.9
Pedunculopontine tegmental nucleus
nTPM: 129.6
2338 Male, age 61, both hemispheres 151.4
2334 Male, age 80, both hemispheres 124.9
1921 Female, age 85, both hemispheres 112.5
Periaquaductal grey, anterior
nTPM: 111.0
2502 Female, age 75, unknown 115.9
1795 Male, age 51, unknown 109.0
1947 Male, age 18, unknown 108.2
Periaquaductal grey, dorsal
nTPM: 121.2
2850 Male, age 76, both hemispheres 132.8
1831 Male, age 72, unknown 119.2
2464 Female, age 72, unknown 119.0
1840 Male, age 53, unknown 114.0
Periaquaductal grey, lateral
nTPM: 123.4
2140 Male, age 76, both hemispheres 127.0
2272 Male, age 74, both hemispheres 122.0
2053 Male, age 18, unknown 121.4
Pretectal area
nTPM: 112.4
2273 Male, age 74, both hemispheres 125.2
2316 Male, age 76, right hemisphere 121.3
2224 Female, age 72, unknown 117.4
2667 Female, age 75, unknown 114.7
2825 Male, age 18, unknown 114.3
1817 Female, age 42, unknown 113.4
1815 Male, age 53, unknown 111.1
1944 Female, age 72, unknown 107.0
2407 Male, age 75, both hemispheres 106.2
2007 Male, age 72, unknown 104.7
1816 Male, age 51, unknown 101.0
Red nucleus
nTPM: 128.7
1821 Female, age 72, unknown 145.6
1954 Female, age 42, unknown 145.0
1865 Male, age 51, unknown 141.6
2769 Male, age 72, unknown 139.7
2227 Male, age 72, unknown 137.6
1904 Male, age 53, unknown 134.1
2823 Male, age 76, right hemisphere 131.6
2503 Female, age 72, unknown 126.4
2785 Male, age 18, unknown 119.0
2725 Female, age 75, unknown 115.3
2588 Male, age 74, left hemisphere 106.7
2584 Male, age 75, left hemisphere 102.1
Substantia nigra
nTPM: 117.4
2699 Male, age 18, unknown 128.1
2409 Female, age 72, unknown 122.8
2590 Female, age 75, unknown 120.3
1851 Male, age 51, unknown 119.6
2241 Male, age 72, unknown 118.7
1941 Male, age 53, unknown 116.1
2665 Male, age 74, both hemispheres 115.0
1916 Female, age 42, unknown 114.5
1889 Female, age 72, unknown 113.5
2583 Male, age 75, right hemisphere 106.0
Superior colliculus
nTPM: 113.6
1913 Female, age 42, unknown 126.2
2587 Male, age 74, left hemisphere 125.7
1995 Male, age 72, unknown 122.6
1839 Male, age 51, unknown 115.6
1895 Male, age 76, right hemisphere 115.0
2668 Female, age 75, unknown 111.1
2087 Female, age 72, unknown 108.1
1796 Male, age 53, unknown 107.1
2261 Male, age 18, unknown 105.9
2664 Male, age 75, both hemispheres 98.7
Ventral tegmental area
nTPM: 122.7
2223 Female, age 72, unknown 131.6
2410 Female, age 72, unknown 126.0
2021 Male, age 53, unknown 125.2
1915 Female, age 42, unknown 122.3
2218 Male, age 76, both hemispheres 118.0
1942 Male, age 51, unknown 113.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 164.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 164.1
Samples: 139

Max nTPM: 311.7
Min nTPM: 75.7
Std nTPM: 47.2
Median nTPM: 154.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 311.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 305.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 299.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 282.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 279.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 277.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 249.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 247.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 241.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 239.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 233.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 232.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 225.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 223.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 223.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 223.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 221.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 219.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 219.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 218.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 215.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 214.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 211.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 208.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 205.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 203.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 201.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 198.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 198.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 197.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 197.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 196.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 191.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 191.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 190.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 188.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 186.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 185.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 185.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 184.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 183.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 182.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 182.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 181.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 180.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 178.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 178.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 177.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 174.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 174.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 174.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 173.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 171.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 171.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 171.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 171.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 170.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 168.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 168.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 168.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 168.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 167.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 167.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 164.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 163.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 162.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 159.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 155.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 155.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 154.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 154.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 154.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 154.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 152.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 150.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 149.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 149.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 149.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 148.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 147.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 147.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 147.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 147.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 147.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 146.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 144.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 143.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 143.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 143.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 142.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 141.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 140.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 139.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 139.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 138.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 138.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 136.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 135.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 135.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 134.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 133.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 133.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 132.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 130.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 130.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 129.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 128.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 127.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 127.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 127.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 126.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 126.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 126.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 124.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 123.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 121.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 119.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 119.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 118.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 118.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 117.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 116.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 113.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 111.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 111.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 106.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 105.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 104.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 101.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 100.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 99.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 98.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 97.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 95.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 92.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 91.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 85.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 82.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 75.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 270.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 270.8
FF:10158-103A5 76 years, female 270.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 28.2
Pig sample Sample description nTPM
Midbrain
nTPM: 28.3
Samples: 4

Max nTPM: 70.9
Min nTPM: 10.3
Sample A Female 70.9
Sample B Female 18.3
Sample C Male 13.5
Sample D Male 10.3
Periaqueductal gray
nTPM: 21.6
Samples: 3

Max nTPM: 22.1
Min nTPM: 21.3
Sample B Female 21.3
Sample C Male 22.1
Sample D Male 21.4
Substantia nigra
nTPM: 26.2
Samples: 4

Max nTPM: 29.9
Min nTPM: 23.5
Sample A Female 29.9
Sample B Female 25.1
Sample C Male 23.5
Sample D Male 26.3
Superior colliculi
nTPM: 18.5
Samples: 4

Max nTPM: 23.9
Min nTPM: 16.2
Sample A Female 16.2
Sample B Female 23.9
Sample C Male 17.7
Sample D Male 16.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 108.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 108.4
Samples: 4

Max nTPM: 112.3
Min nTPM: 103.2
Sample A Male 112.3
Sample B Male 108.7
Sample C Female 103.2
Sample D Female 109.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 4.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.4
77454635 Antisense, RP_070129_01_B05, Mouse strain C57BL/6J (56 days, male) 4.4
79488933 Antisense, RP_070129_01_B05, Mouse strain C57BL/6J (56 days, male) 2.4

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