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ANKRD33B
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                                • ANKRD33B
                                PROTEIN SUMMARY SECTION OVERVIEW RNA DATA ANTIBODY DATA
                                RNA SUMMARY - Normalized
                                Tissue consensus dataseti

                                The consensus dataset consists of normalized expression (nTPM) levels for 55 tissue types, created by combining the HPA and GTEx transcriptomics datasets using the internal normalization pipeline. Color-coding is based on tissue groups, each consisting of tissues with functional features in common. To access sample data, click on tissue name or bar.

                                Read more about how the datasets were combined into consensus normalized expression levels in <a href="/about/assays+annotation#normalization_rna"_blank">Assays & Annotation.

                                Cerebral cortexCerebellumChoroid plexusBasal gangliaThalamusHypothalamusMidbrainPonsMedulla oblongataHippocampal formationSpinal cordWhite matterAmygdalaRetinaThyroid glandParathyroid glandAdrenal glandPituitary glandLungSalivary glandEsophagusTongueStomachDuodenumSmall intestineColonRectumLiverGallbladderPancreasKidneyUrinary bladderTestisEpididymisSeminal vesicleProstateVaginaOvaryFallopian tubeEndometriumCervixPlacentaBreastHeart muscleSmooth muscleSkeletal muscleAdipose tissueSkinAppendixSpleenLymph nodeTonsilBone marrowThymus0102030405060nTPM
                                Single cell typei

                                A summary of normalized single cell RNA (nTPM) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.

                                Basal respiratory cellsClub cellsIonocytesRespiratory ciliated cellsMucus glandular cellsSerous glandular cellsGastric mucus-secreting cellsProximal enterocytesPaneth cellsDistal enterocytesIntestinal goblet cellsExocrine glandular cellsBasal prostatic cellsProstatic glandular cellsBreast glandular cellsBreast myoepithelial cellsEndometrial ciliated cellsGlandular and luminal cellsBasal keratinocytesSuprabasal keratinocytesBasal squamous epithelial cellsSquamous epithelial cellsAlveolar cells type 1Alveolar cells type 2Salivary duct cellsDuctal cellsHepatocytesCholangiocytesProximal tubular cellsDistal tubular cellsCollecting duct cellsThymic epithelial cellsSertoli cellsGranulosa cellsEnteroendocrine cellsPancreatic endocrine cellsLeydig cellsTheca cellsExcitatory neuronsInhibitory neuronsCone photoreceptor cellsRod photoreceptor cellsBipolar cellsHorizontal cellsAstrocytesOligodendrocyte precursor cellsOligodendrocytesMicroglial cellsMuller glia cellsSchwann cellsSpermatogoniaSpermatocytesEarly spermatidsLate spermatidsCytotrophoblastsSyncytiotrophoblastsExtravillous trophoblastsEndothelial cellsCardiomyocytesSkeletal myocytesSmooth muscle cellsAdipocytesMelanocytesFibroblastsPeritubular cellsEndometrial stromal cellsUndifferentiated cellsT-cellsB-cellsPlasma cellsNk-cellsGranulocytesMonocytesMacrophagesHofbauer cellsKupffer cellsDendritic cellsLangerhans cellsErythroid cells050100150200250300350nTPM
                                Brain regional consensus dataseti

                                Consensus normalized expression (nTPM) levels were created for the 13 brain regions based on the HPA brain transcriptomics dataset. Color-coding is based on the brain region, in several cases consisting of the highest expression among the subregions included. To access sample data, click on region name or bar.

                                Read more about normalization of transcriptomics data in<a href="/about/assays+annotation#normalization_rna"_blank">Assays & Annotation.

                                Cerebral cortexHippocampal formationAmygdalaBasal gangliaThalamusHypothalamusMidbrainCerebellumPonsMedulla oblongataSpinal cordWhite matter0510152025nTPM
                                HPA immune cell dataseti

                                The resulting transcript expression values calculated as nTPM, resulting from the internal normalization pipeline for 18 immune cell types and total peripheral blood mononuclear cells (PBMC).

                                Read more
                                BasophilEosinophilNeutrophilClassical monocyteNon-classical monocyteIntermediate monocyteT-regGdT-cellMAIT T-cellMemory CD4 T-cellNaive CD4 T-cellMemory CD8 T-cellNaive CD8 T-cellMemory B-cellNaive B-cellPlasmacytoid DCMyeloid DCNK-cellTotal PBMC0246810nTPM
                                HPA cell linesi

                                The cell lines in the Human Protein Atlas have been analyzed by RNA-seq to estimate the transcript abundance of each protein-coding gene. The RNA-seq data was then used to classify all genes according to their cell line-specific expression into one of six different categories, defined based on the total set of all nTPM values in all analyzed cell lines.

                                Bile duct cancerBladder cancerBone cancerBrain cancerBreast cancerCervical cancerColorectal cancerUterine cancerEsophageal cancerGallbladder cancerGastric cancerHead and Neck cancerKidney cancerLeukemiaLiver cancerLung cancerLymphomaMyelomaNeuroblastomaNon-cancerousOvarian cancerPancreatic cancerProstate cancerRhabdoidSarcomaSkin cancerTestis cancerThyroid cancerUncategorized0510152025nTPM

                                RNA SAMPLE SUMMARYi

                                The RNA summary section shows normal distribution of individual samples across the datasets of multiple RNA-seq analyses visualized with box plots shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range.

                                Hold mouse pointer over tissue/cell type/cell line to see sample numbers. Click on the cancer type to see cancer type sample information.

                                HPA tissue dataset
                                0.05.010.015.020.025.030.035.040.045.0nTPMLungSalivary glandEsophagusStomachDuodenumSmall intestineColonRectumAppendixLiverGallbladderPancreasThyroid glandParathyroid glandAdrenal glandKidneyUrinary bladderSkinOvaryFallopian tubeEndometriumCervixPlacentaBreastTestisEpididymisSeminal vesicleProstateHippocampusSpleenLymph nodeTonsilBone marrowHeart muscleSmooth muscleSkeletal muscleAdipose tissueAmygdalaAngular gyrusAngular gyrus (white matter)Anterior cingulate cortex, supragenual-dorsalAnterior cingulate cortex, supragenual-ventralAnterior cingulate gyrus, pregenual-dorsalAnterior cingulate gyrus, pregenual-ventralAnterior cingulate gyrus, subgenualAnterior cochlear nucleus, ventralAnterior funiculus (white matter)Anterior insular cortex, dorsalAnterior insular cortex, ventralAnterior thalamic nucleus, ventralArcuate nucleusArea parastriata, inferiorArea parastriata, parietalArea parastriata, superiorArea parastriata, temporalArea postremaArea striataArea striata (white matter)Basal amygdalaCaudate nucleusCentral amygdalaCentromedial thalamic nucleusCerebellar cortexCerebellar nucleiCerebellar white matterCervical spinal cord, central grayCervical spinal cord, dorsal hornCervical spinal cord, ventral hornChoroid plexusClaustrumCorpus callosum, genu (white matter)Corpus callosum, splenium (white matter)Corticomedial amygdalaCuneate nucleiCuneiform nucleusDentate gyrusDorsal cochlear nucleusDorsal funiculus (white matter)Dorsal medullary reticular nucleusDorsal motor vagal complexDorsal raphe nucleusDorsal tegmental nucleusDorsolateral prefrontal cortexDorsolateral tegmental areaDorsomedial nucleusDorsomedial prefrontal cortexEntorhinal gyrusFlocculonodular lobeFrontal cortexFrontal eye fieldFrontal operculumFrontomarginal cortexFrontopolar cortexFusiform gyrusGigantocellular reticular nuclei, medullaryGigantocellular reticular nuclei, parsGlobus pallidus, externusGlobus pallidus, internusGyrus rectusHabenulaHippocampus, CA1Hippocampus, CA2Hippocampus, CA3Inferior colliculusInferior frontal gyrus, opercularInferior frontal gyrus, orbitalInferior frontal gyrus, triangularInferior oliveInferior parietal lobuleInferior temporal gyrusIntraparietal deep sulcusKolliker-Fuse nucleusLateral amygdalaLateral funiculus (white matter)Lateral geniculate bodyLateral hypothalamic areaLateral lemniscal nucleiLateral medullary reticular nucleusLateral parabrachial nucleusLateral thalamic nucleiLateral vestibular nucleusLingual gyrusLocus coeruleusMamillary bodyMedial dorsal thalamic nucleusMedial geniculate bodyMedial olivary nucleusMedial parabrachial nucleusMedial periolivary nucleiMedial vestibular nucleusMedian raphe nucleusMiddle cingulate cortexMiddle frontal gyrusMiddle temporal gyrusMotor facial nucleusMotor hypoglossal nucleusMotor trigeminal nucleusNuclei of the trapezoid bodyNucleus accumbensNucleus ambiguusNucleus basalis of MeynertNucleus cuneatusNucleus gracilisNucleus of the diagonal bandNucleus raphe magnusNucleus raphe obscurusNucleus raphe pallidusNucleus reuniensNucleus rhomboideusNucleus tractus solitariiOccipital cortexOccipital cortex (white matter)Olfactory areaOlfactory tubercleOrbitofrontal gyrus, anteriorOrbitofrontal gyrus, lateralOrbitofrontal gyrus, medialOrbitofrontal gyrus, posteriorParacentral lobule, anteriorParacentral lobule, posteriorParahippocampal cortexParahippocampal cortex (white matter)Paramedian reticular nucleusParaventricular nucleusParietal cortexParietal operculumParieto-insular cortexParieto-occipital transitional areaParieto-temporal junction (white matter)Parvicellular reticular nucleiParvicellular reticular nuclei, medullaryPedunculopontine tegmental nucleusPeriaquaductal grey, anteriorPeriaquaductal grey, dorsalPeriaquaductal grey, lateralPerirhinal gyrusPeritrigeminal nucleusPiriform cortexPontine nucleiPontine raphe nucleusPostcentral gyrusPostcentral gyrus, dorsalPostcentral gyrus, middlePostcentral gyrus, ventralPosterior cingulate cortexPosterior cingulate cortex, dorsalPosterior cingulate cortex, ventralPosterior insular cortexPosterior thalamic nucleusPosteroventral cochlear nucleusPrecentral gyrusPrecentral gyrus, dorsalPrecentral gyrus, middlePrecentral gyrus, ventralPrecuneusPremotor cortex, dorsalPremotor cortex, ventralPreoptic areaPrepositus hypoglossal nucleusPretectal areaPrincipal sensory trigeminal nucleusPulvinarPutamenRed nucleusReticular pontine nucleus, caudalReticular pontine nucleus, oralReticulotegmental nucleusRetrosplenial cortexSeptal nucleiSomatomor cortex, precentral gyrus (white matter)Somatosensory cortex, postcentral gyrus, ventral (white matter)Spinal trigeminal nucleus, caudalSpinal trigeminal nucleus, interpolarSpinal trigeminal nucleus, oralSpinal vestibular nucleusStria terminalis, bed nucleusSubcallosal gyrusSubcentral gyrus, S2Subcoeruleus areaSubiculumSubstantia nigraSubthalamic nucleusSuperior colliculusSuperior frontal gyrusSuperior oliveSuperior parietal lobuleSuperior temporal gyrusSuperior vestibular nucleusSupplementary motor cortexSupramarginal gyrusSupraoptic nucleusTemporal cortexTemporal poleTemporal white matterTemporo-insular cortex, parainsular gyrusTemporo-occipital transitional zoneThymusTongueTransversal temporal gyrus, anteriorTransversal temporal gyrus, posteriorVentral medullary reticular nucleusVentral periolivary nucleiVentral posterolateral thalamic nucleusVentral posteromedial thalamic nucleusVentral tegmental areaVentral thalamic nucleiVentrolateral medulla, A1-C1 cell groupsVentrolateral prefrontal cortexVentrolateral tegmental area, A5 NE cell groupVentromedial nucleusVentromedial prefrontal cortexVermisZona incerta
                                GTEx tissue dataset
                                0.010.020.030.040.050.060.070.080.0nTPMRetinaLungSalivary glandEsophagusStomachSmall intestineColonLiverPancreasThyroid glandAdrenal glandKidneyUrinary bladderVaginaSkinOvaryFallopian tubeEndometriumCervixBreastTestisProstateCerebral cortexCerebellumHippocampusCaudateSpleenHeart muscleSkeletal muscleAdipose tissueAmygdalaHypothalamusNucleus accumbensPituitary glandPutamenSpinal cordSubstantia nigra
                                FANTOM5 tissue dataset
                                0.010.020.030.040.050.060.070.080.090.0Scaled Tags Per MillionLungSalivary glandEsophagusSmall intestineColonAppendixLiverGallbladderPancreasThyroid glandKidneyUrinary bladderVaginaOvaryEndometriumCervixPlacentaBreastTestisEpididymisSeminal vesicleProstateCerebellumHippocampusCaudateSpleenLymph nodeTonsilHeart muscleSmooth muscleSkeletal muscleAdipose tissueAmygdalaCorpus callosumDuctus deferensFrontal lobeGlobus pallidusInsular cortexLocus coeruleusMedial frontal gyrusMedial temporal gyrusMedulla oblongataNucleus accumbensOccipital cortexOccipital lobeOccipital poleOlfactory bulbParacentral gyrusParietal lobePituitary glandPonsPostcentral gyrusPutamenRetinaSpinal cordSubstantia nigraTemporal cortexThalamusThymusTongue
                                HPA immune cell dataset
                                0.00.10.20.30.40.50.60.70.8nTPMBasophilClassical monocyteEosinophilGdT-cellIntermediate monocyteMAIT T-cellMemory B-cellMemory CD4 T-cellMemory CD8 T-cellMyeloid DCNaive B-cellNaive CD4 T-cellNaive CD8 T-cellNeutrophilNK-cellNon-classical monocytePlasmacytoid DCT-regTotal PBMC
                                Monaco immune cell dataset
                                0.00.51.01.52.02.53.03.54.04.55.05.56.06.5nTPMBasophilCentral memory CD8 T-cellClassical monocyteEffector memory CD8 T-cellExhausted memory B-cellIntermediate monocyteMAIT T-cellMemory CD4 T-cell TFHMemory CD4 T-cell Th1Memory CD4 T-cell Th1/Th17Memory CD4 T-cell Th17Memory CD4 T-cell Th2Myeloid DCNaive B-cellNaive CD4 T-cellNaive CD8 T-cellNeutrophilNK-cellNon-classical monocyteNon-switched memory B-cellNon-Vd2 gdTCRPlasmablastPlasmacytoid DCProgenitor cellSwitched memory B-cellT-regTerminal effector memory CD4 T-cellTerminal effector memory CD8 T-cellTotal PBMCVd2 gdTCR
                                Schmiedel immune cell dataset
                                0.00.51.01.52.02.53.03.5TPMClassical monocyteMemory CD4 T-cell TFHMemory CD4 T-cell Th1Memory CD4 T-cell Th1/Th17Memory CD4 T-cell Th17Memory CD4 T-cell Th2Memory T-regNaive B-cellNaive CD4 T-cellNaive CD4 T-cell activatedNaive CD8 T-cellNaive CD8 T-cell activatedNaive T-regNK-cellNon-classical monocyte
                                Pig brain dataset
                                0.05.010.015.020.025.030.0nTPMCerebellumCaudateAmygdalaCingulate cortexCorpus callosumDorsal hippocampus Dorsal spinal cordEntorhinal cortexHypothalamusInsular cortexMedulla oblongataMidbrainMotor cortexOccipital cortexOlfactory bulbPeriaqueductal grayPituitary glandPonsPrefrontal cortexPutamenRetinaRetrosplenial cortexSeptumSomatosensory cortexSubiculumSubstantia nigraSuperior colliculiTemporal cortexThalamusVentral hippocampus Ventral pallidumVentral spinal cord
                                Mouse brain dataset
                                0.010.020.030.040.050.060.070.080.090.0100.0110.0nTPMCerebellumAmygdalaCaudate putamenCorpus callosumEntorhinal cortexFrontal cortexHippocampal formationHypothalamusMidbrainOccipital cortexOlfactory bulbPituitary glandPons and medullaRetinaRetrosplenial and cingulate cortexSeptumSomatosensory cortexThalamusVentral forebrain
                                Allen mouse brain dataset
                                0.00.10.20.30.40.50.60.70.80.91.01.1Expression energyCerebellumPonsOlfactory bulbHypothalamusThalamusHippocampal formationMidbrainMedulla oblongataStriatumCortical subplatePallidum
                                Cell line dataset
                                0.05.010.015.020.025.030.035.040.045.0nTPMA-431A-549AF22ASC52teloBJ [Human fibroblast]CACO-2EFO-21FHDF/TERT166GAMGHaCaTHAP1HBEC3-KTHBF/TERT88HDLM-2HEK293HELHeLaHep-G2HTCEpiHTEC/SVTERT24-BHTERT-HME1HTERT-RPE1HUVEC/TERT2JURKATK-562LHCN-M2MCF-7NB4OE19PC-3REHRh30RPTEC/TERT1RT-4SH-SY5YSiHaSK-MEL-30SuSaTHP-1U-251MGU2OS
                                TCGA dataset
                                0.010.020.030.040.050.060.070.0FPKMGliomaThyroid cancerLung cancerColorectal cancerHead and neck cancerStomach cancerLiver cancerPancreatic cancerRenal cancerUrothelial cancerProstate cancerTestis cancerBreast cancerCervical cancerEndometrial cancerOvarian cancerMelanoma

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