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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:8.9 nTPM
HPA:8.9 nTPM
GTEx:14.7 nTPM
FANTOM5:23.1 Scaled Tags Per Million
Pig:24.6 nTPM
Mouse:33.4 nTPM
Allen mouse:0.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 8.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 7.4
2828 Female, age 72, unknown 8.4
1827 Male, age 72, unknown 8.1
1870 Female, age 42, unknown 7.7
2586 Male, age 75, left hemisphere 7.5
1830 Male, age 51, unknown 7.2
1833 Male, age 53, unknown 7.2
2019 Male, age 18, unknown 7.1
2411 Female, age 72, unknown 7.1
2219 Male, age 76, both hemispheres 7.0
2666 Male, age 74, left hemisphere 6.9
Dorsal raphe nucleus
nTPM: 8.2
2298 Female, age 72, unknown 9.0
2016 Female, age 72, unknown 8.6
1828 Male, age 53, unknown 8.3
2047 Male, age 72, unknown 8.2
2750 Male, age 76, both hemispheres 6.9
Inferior colliculus
nTPM: 8.9
2097 Female, age 72, unknown 9.5
1848 Female, age 42, unknown 8.9
1890 Male, age 53, unknown 8.7
2849 Male, age 72, unknown 8.5
Median raphe nucleus
nTPM: 7.3
2220 Male, age 76, midline 7.3
Pedunculopontine tegmental nucleus
nTPM: 6.9
1921 Female, age 85, both hemispheres 7.4
2334 Male, age 80, both hemispheres 7.0
2338 Male, age 61, both hemispheres 6.4
Periaquaductal grey, anterior
nTPM: 7.7
1795 Male, age 51, unknown 8.1
2502 Female, age 75, unknown 7.7
1947 Male, age 18, unknown 7.4
Periaquaductal grey, dorsal
nTPM: 8.1
1840 Male, age 53, unknown 8.6
2464 Female, age 72, unknown 8.2
1831 Male, age 72, unknown 7.7
2850 Male, age 76, both hemispheres 7.7
Periaquaductal grey, lateral
nTPM: 7.9
2053 Male, age 18, unknown 8.4
2272 Male, age 74, both hemispheres 7.8
2140 Male, age 76, both hemispheres 7.5
Pretectal area
nTPM: 7.8
2825 Male, age 18, unknown 8.8
2273 Male, age 74, both hemispheres 8.5
1816 Male, age 51, unknown 8.4
2667 Female, age 75, unknown 8.4
2224 Female, age 72, unknown 8.2
1944 Female, age 72, unknown 7.9
2316 Male, age 76, right hemisphere 7.8
2407 Male, age 75, both hemispheres 7.3
1815 Male, age 53, unknown 7.2
1817 Female, age 42, unknown 7.1
2007 Male, age 72, unknown 6.8
Red nucleus
nTPM: 7.3
2725 Female, age 75, unknown 8.2
2503 Female, age 72, unknown 7.8
1954 Female, age 42, unknown 7.6
1821 Female, age 72, unknown 7.5
2588 Male, age 74, left hemisphere 7.5
2769 Male, age 72, unknown 7.5
2227 Male, age 72, unknown 7.4
2823 Male, age 76, right hemisphere 7.2
2584 Male, age 75, left hemisphere 7.0
1865 Male, age 51, unknown 6.8
1904 Male, age 53, unknown 6.5
2785 Male, age 18, unknown 6.2
Substantia nigra
nTPM: 7.7
1941 Male, age 53, unknown 8.9
2665 Male, age 74, both hemispheres 8.2
2583 Male, age 75, right hemisphere 8.0
2241 Male, age 72, unknown 7.9
2699 Male, age 18, unknown 7.6
1916 Female, age 42, unknown 7.5
2409 Female, age 72, unknown 7.5
2590 Female, age 75, unknown 7.3
1851 Male, age 51, unknown 7.2
1889 Female, age 72, unknown 7.0
Superior colliculus
nTPM: 7.9
2664 Male, age 75, both hemispheres 8.9
2087 Female, age 72, unknown 8.6
2261 Male, age 18, unknown 8.5
1839 Male, age 51, unknown 8.2
1995 Male, age 72, unknown 8.1
1895 Male, age 76, right hemisphere 7.8
1796 Male, age 53, unknown 7.6
2587 Male, age 74, left hemisphere 7.3
1913 Female, age 42, unknown 7.1
2668 Female, age 75, unknown 6.8
Ventral tegmental area
nTPM: 7.3
2223 Female, age 72, unknown 8.0
1915 Female, age 42, unknown 7.6
2021 Male, age 53, unknown 7.6
1942 Male, age 51, unknown 7.4
2218 Male, age 76, both hemispheres 6.8
2410 Female, age 72, unknown 6.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 14.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 14.7
Samples: 139

Max nTPM: 41.0
Min nTPM: 3.8
Std nTPM: 6.2
Median nTPM: 13.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 41.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 35.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 33.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 31.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 29.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 29.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 27.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 27.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 26.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 25.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 24.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 23.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 23.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 23.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 23.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 22.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 21.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 21.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 20.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 20.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 19.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 18.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 18.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 18.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 18.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 18.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 18.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 18.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 18.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 18.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 17.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 17.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 17.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 17.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 17.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 17.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 17.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 16.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 16.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 16.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 16.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 16.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 16.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 15.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 15.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 15.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 15.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 15.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 15.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 15.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 15.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 15.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 15.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 15.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 15.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 15.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 15.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 15.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 14.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 14.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 14.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 14.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 14.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 14.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 14.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 13.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 13.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 13.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 13.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 13.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 13.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 13.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 13.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 13.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 13.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 13.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 12.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 12.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 12.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 12.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 12.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 12.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 12.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 12.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 12.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 12.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 12.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 12.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 12.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 11.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 11.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 11.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 11.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 11.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 11.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 11.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 11.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 11.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 11.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 11.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 11.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 10.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 10.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 10.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 10.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 10.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 10.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 10.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 10.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 10.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 10.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 10.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 9.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 9.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 9.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 9.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 9.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 8.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 8.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 8.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 8.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 8.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 8.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 8.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 7.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 7.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 7.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 7.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 7.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 7.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 6.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 6.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 6.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 6.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 6.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 6.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 6.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 5.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 3.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 23.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 23.1
FF:10158-103A5 76 years, female 23.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 24.6
Pig sample Sample description nTPM
Midbrain
nTPM: 14.2
Samples: 4

Max nTPM: 21.3
Min nTPM: 10.1
Sample A Female 21.3
Sample B Female 12.5
Sample C Male 12.7
Sample D Male 10.1
Periaqueductal gray
nTPM: 10.7
Samples: 3

Max nTPM: 11.1
Min nTPM: 10.5
Sample B Female 10.5
Sample C Male 10.5
Sample D Male 11.1
Substantia nigra
nTPM: 15.0
Samples: 4

Max nTPM: 18.4
Min nTPM: 12.2
Sample A Female 16.4
Sample B Female 18.4
Sample C Male 12.2
Sample D Male 12.8
Superior colliculi
nTPM: 24.7
Samples: 4

Max nTPM: 49.0
Min nTPM: 11.8
Sample A Female 25.5
Sample B Female 49.0
Sample C Male 12.3
Sample D Male 11.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 33.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 33.4
Samples: 4

Max nTPM: 38.0
Min nTPM: 31.5
Sample A Male 38.0
Sample B Male 31.7
Sample C Female 32.4
Sample D Female 31.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.8
1652 Antisense, RP_040604_01_D10, Mouse strain C57BL/6J (56 days, male) 0.8
1651 Antisense, RP_040604_01_D10, Mouse strain C57BL/6J (56 days, male) 0.3

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