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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:107.1 nTPM
HPA:107.1 nTPM
GTEx:126.4 nTPM
FANTOM5:56.6 Scaled Tags Per Million
Pig:165.2 nTPM
Mouse:292.9 nTPM
Allen mouse:5.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 107.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 92.9
2019 Male, age 18, unknown 111.6
2411 Female, age 72, unknown 103.4
1827 Male, age 72, unknown 95.4
2219 Male, age 76, both hemispheres 91.1
1870 Female, age 42, unknown 91.0
2828 Female, age 72, unknown 91.0
1833 Male, age 53, unknown 88.7
1830 Male, age 51, unknown 88.5
2666 Male, age 74, left hemisphere 84.2
2586 Male, age 75, left hemisphere 84.0
Dorsal raphe nucleus
nTPM: 98.5
2298 Female, age 72, unknown 106.8
1828 Male, age 53, unknown 104.0
2047 Male, age 72, unknown 97.6
2750 Male, age 76, both hemispheres 96.4
2016 Female, age 72, unknown 87.5
Inferior colliculus
nTPM: 92.7
2097 Female, age 72, unknown 101.6
1890 Male, age 53, unknown 94.7
1848 Female, age 42, unknown 91.3
2849 Male, age 72, unknown 83.2
Median raphe nucleus
nTPM: 95.8
2220 Male, age 76, midline 95.8
Pedunculopontine tegmental nucleus
nTPM: 97.1
1921 Female, age 85, both hemispheres 99.9
2334 Male, age 80, both hemispheres 97.9
2338 Male, age 61, both hemispheres 93.6
Periaquaductal grey, anterior
nTPM: 91.4
2502 Female, age 75, unknown 93.2
1947 Male, age 18, unknown 90.6
1795 Male, age 51, unknown 90.5
Periaquaductal grey, dorsal
nTPM: 87.4
2850 Male, age 76, both hemispheres 88.3
1840 Male, age 53, unknown 87.7
2464 Female, age 72, unknown 87.3
1831 Male, age 72, unknown 86.4
Periaquaductal grey, lateral
nTPM: 88.4
2272 Male, age 74, both hemispheres 93.9
2140 Male, age 76, both hemispheres 86.7
2053 Male, age 18, unknown 84.4
Pretectal area
nTPM: 99.9
2007 Male, age 72, unknown 111.9
1816 Male, age 51, unknown 111.3
1944 Female, age 72, unknown 111.1
1817 Female, age 42, unknown 108.4
2667 Female, age 75, unknown 105.3
1815 Male, age 53, unknown 101.0
2273 Male, age 74, both hemispheres 96.8
2224 Female, age 72, unknown 93.8
2316 Male, age 76, right hemisphere 89.8
2825 Male, age 18, unknown 86.7
2407 Male, age 75, both hemispheres 82.4
Red nucleus
nTPM: 96.3
1821 Female, age 72, unknown 108.6
2785 Male, age 18, unknown 104.0
2503 Female, age 72, unknown 98.2
2823 Male, age 76, right hemisphere 98.0
2725 Female, age 75, unknown 97.3
1904 Male, age 53, unknown 95.8
1865 Male, age 51, unknown 95.5
1954 Female, age 42, unknown 94.8
2227 Male, age 72, unknown 93.0
2769 Male, age 72, unknown 92.9
2588 Male, age 74, left hemisphere 89.0
2584 Male, age 75, left hemisphere 88.4
Substantia nigra
nTPM: 107.1
1916 Female, age 42, unknown 124.5
2241 Male, age 72, unknown 121.8
2409 Female, age 72, unknown 115.2
1851 Male, age 51, unknown 112.0
1889 Female, age 72, unknown 109.9
1941 Male, age 53, unknown 108.1
2665 Male, age 74, both hemispheres 97.9
2699 Male, age 18, unknown 96.4
2590 Female, age 75, unknown 95.1
2583 Male, age 75, right hemisphere 89.6
Superior colliculus
nTPM: 92.3
2087 Female, age 72, unknown 105.6
1895 Male, age 76, right hemisphere 98.4
2587 Male, age 74, left hemisphere 96.2
2261 Male, age 18, unknown 94.1
1796 Male, age 53, unknown 92.7
2668 Female, age 75, unknown 92.2
1839 Male, age 51, unknown 88.6
1913 Female, age 42, unknown 87.2
1995 Male, age 72, unknown 86.4
2664 Male, age 75, both hemispheres 81.4
Ventral tegmental area
nTPM: 99.8
2410 Female, age 72, unknown 113.7
1915 Female, age 42, unknown 107.2
2218 Male, age 76, both hemispheres 101.7
2223 Female, age 72, unknown 93.2
1942 Male, age 51, unknown 93.1
2021 Male, age 53, unknown 89.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 126.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 126.4
Samples: 139

Max nTPM: 261.7
Min nTPM: 69.7
Std nTPM: 32.8
Median nTPM: 120.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 261.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 236.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 228.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 214.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 204.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 198.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 193.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 182.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 180.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 176.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 173.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 170.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 166.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 164.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 161.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 161.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 161.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 160.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 158.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 158.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 158.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 156.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 155.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 152.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 151.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 151.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 150.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 149.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 148.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 148.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 148.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 145.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 145.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 144.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 143.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 142.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 141.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 141.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 140.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 140.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 140.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 138.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 137.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 136.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 135.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 134.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 133.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 133.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 132.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 131.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 131.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 131.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 130.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 128.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 128.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 127.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 127.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 126.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 126.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 125.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 125.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 124.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 124.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 124.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 123.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 123.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 122.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 121.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 121.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 120.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 120.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 120.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 120.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 119.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 119.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 119.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 119.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 118.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 117.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 116.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 116.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 115.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 113.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 112.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 112.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 111.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 110.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 108.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 108.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 108.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 108.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 108.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 107.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 107.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 107.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 106.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 106.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 106.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 105.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 104.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 104.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 103.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 103.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 103.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 102.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 102.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 102.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 102.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 102.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 102.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 102.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 101.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 101.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 100.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 100.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 98.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 98.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 97.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 97.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 97.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 97.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 96.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 91.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 91.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 90.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 88.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 87.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 87.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 87.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 85.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 85.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 85.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 85.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 84.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 81.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 78.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 77.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 72.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 69.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 56.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 56.6
FF:10158-103A5 76 years, female 56.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 165.2
Pig sample Sample description nTPM
Midbrain
nTPM: 153.6
Samples: 4

Max nTPM: 183.7
Min nTPM: 131.0
Sample A Female 183.7
Sample B Female 131.0
Sample C Male 166.4
Sample D Male 133.4
Periaqueductal gray
nTPM: 107.7
Samples: 3

Max nTPM: 120.3
Min nTPM: 95.7
Sample B Female 107.2
Sample C Male 120.3
Sample D Male 95.7
Substantia nigra
nTPM: 140.0
Samples: 4

Max nTPM: 178.0
Min nTPM: 111.0
Sample A Female 178.0
Sample B Female 111.0
Sample C Male 148.8
Sample D Male 122.2
Superior colliculi
nTPM: 165.2
Samples: 4

Max nTPM: 202.3
Min nTPM: 123.3
Sample A Female 185.2
Sample B Female 123.3
Sample C Male 202.3
Sample D Male 149.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 292.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 292.9
Samples: 4

Max nTPM: 300.9
Min nTPM: 281.5
Sample A Male 289.8
Sample B Male 300.9
Sample C Female 281.5
Sample D Female 299.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 5.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 5.7
1888 Antisense, RP_Baylor_103100, Mouse strain C57BL/6J (56 days, male) 5.7
1889 Antisense, RP_Baylor_103100, Mouse strain C57BL/6J (56 days, male) 1.3

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