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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:97.1 nTPM
HPA:97.1 nTPM
GTEx:106.5 nTPM
FANTOM5:172.6 Scaled Tags Per Million
Pig:136.5 nTPM
Mouse:139.9 nTPM
Allen mouse:3.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 97.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 91.3
2411 Female, age 72, unknown 97.8
2019 Male, age 18, unknown 97.3
1870 Female, age 42, unknown 94.9
1827 Male, age 72, unknown 91.3
2666 Male, age 74, left hemisphere 90.0
2828 Female, age 72, unknown 90.0
1833 Male, age 53, unknown 89.9
2219 Male, age 76, both hemispheres 87.7
1830 Male, age 51, unknown 87.4
2586 Male, age 75, left hemisphere 86.9
Dorsal raphe nucleus
nTPM: 97.1
2298 Female, age 72, unknown 104.8
1828 Male, age 53, unknown 97.0
2047 Male, age 72, unknown 95.9
2016 Female, age 72, unknown 94.2
2750 Male, age 76, both hemispheres 93.7
Inferior colliculus
nTPM: 93.9
2097 Female, age 72, unknown 100.8
1890 Male, age 53, unknown 95.1
1848 Female, age 42, unknown 93.2
2849 Male, age 72, unknown 86.3
Median raphe nucleus
nTPM: 91.4
2220 Male, age 76, midline 91.4
Pedunculopontine tegmental nucleus
nTPM: 93.0
1921 Female, age 85, both hemispheres 95.5
2334 Male, age 80, both hemispheres 94.6
2338 Male, age 61, both hemispheres 88.9
Periaquaductal grey, anterior
nTPM: 92.2
1947 Male, age 18, unknown 94.1
2502 Female, age 75, unknown 92.1
1795 Male, age 51, unknown 90.5
Periaquaductal grey, dorsal
nTPM: 91.2
1840 Male, age 53, unknown 92.4
2464 Female, age 72, unknown 92.1
1831 Male, age 72, unknown 90.4
2850 Male, age 76, both hemispheres 89.9
Periaquaductal grey, lateral
nTPM: 89.5
2272 Male, age 74, both hemispheres 92.5
2053 Male, age 18, unknown 89.0
2140 Male, age 76, both hemispheres 87.0
Pretectal area
nTPM: 94.2
1817 Female, age 42, unknown 98.7
2224 Female, age 72, unknown 97.4
2667 Female, age 75, unknown 97.1
1816 Male, age 51, unknown 97.0
2273 Male, age 74, both hemispheres 96.7
1944 Female, age 72, unknown 96.2
2007 Male, age 72, unknown 96.1
1815 Male, age 53, unknown 92.6
2316 Male, age 76, right hemisphere 91.3
2825 Male, age 18, unknown 88.7
2407 Male, age 75, both hemispheres 84.3
Red nucleus
nTPM: 93.3
1821 Female, age 72, unknown 104.6
1954 Female, age 42, unknown 96.4
2227 Male, age 72, unknown 94.9
1904 Male, age 53, unknown 94.5
2725 Female, age 75, unknown 94.4
2769 Male, age 72, unknown 94.2
2503 Female, age 72, unknown 94.0
2823 Male, age 76, right hemisphere 92.6
1865 Male, age 51, unknown 92.5
2785 Male, age 18, unknown 92.5
2588 Male, age 74, left hemisphere 87.1
2584 Male, age 75, left hemisphere 82.1
Substantia nigra
nTPM: 96.1
2241 Male, age 72, unknown 105.6
1916 Female, age 42, unknown 102.8
1851 Male, age 51, unknown 101.9
1889 Female, age 72, unknown 99.2
1941 Male, age 53, unknown 96.5
2409 Female, age 72, unknown 96.4
2699 Male, age 18, unknown 93.0
2590 Female, age 75, unknown 89.9
2665 Male, age 74, both hemispheres 88.2
2583 Male, age 75, right hemisphere 86.9
Superior colliculus
nTPM: 91.2
2587 Male, age 74, left hemisphere 95.4
1895 Male, age 76, right hemisphere 94.8
2087 Female, age 72, unknown 94.0
2668 Female, age 75, unknown 92.1
2261 Male, age 18, unknown 91.7
1839 Male, age 51, unknown 91.2
1796 Male, age 53, unknown 90.6
1913 Female, age 42, unknown 88.9
1995 Male, age 72, unknown 87.5
2664 Male, age 75, both hemispheres 85.9
Ventral tegmental area
nTPM: 95.2
2410 Female, age 72, unknown 101.7
1915 Female, age 42, unknown 98.8
2218 Male, age 76, both hemispheres 95.9
1942 Male, age 51, unknown 92.6
2021 Male, age 53, unknown 92.1
2223 Female, age 72, unknown 90.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 106.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 106.5
Samples: 139

Max nTPM: 172.9
Min nTPM: 57.4
Std nTPM: 20.3
Median nTPM: 104.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 172.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 164.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 156.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 154.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 152.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 152.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 149.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 142.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 137.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 136.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 136.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 134.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 134.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 133.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 130.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 130.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 130.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 129.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 129.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 126.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 126.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 126.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 126.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 126.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 126.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 125.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 121.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 121.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 120.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 118.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 117.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 116.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 116.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 116.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 116.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 116.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 116.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 116.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 116.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 115.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 115.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 114.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 114.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 114.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 113.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 113.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 113.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 112.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 112.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 112.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 112.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 111.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 111.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 111.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 110.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 109.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 109.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 109.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 108.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 108.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 108.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 108.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 107.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 107.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 106.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 105.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 105.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 104.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 104.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 104.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 103.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 102.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 102.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 102.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 102.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 102.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 101.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 101.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 101.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 101.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 100.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 100.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 100.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 100.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 100.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 99.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 98.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 98.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 98.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 97.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 97.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 97.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 96.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 95.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 95.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 95.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 95.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 94.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 94.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 94.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 94.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 93.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 93.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 93.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 93.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 93.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 92.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 92.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 91.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 91.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 90.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 90.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 90.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 90.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 90.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 89.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 89.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 88.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 87.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 86.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 85.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 84.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 84.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 83.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 82.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 81.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 81.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 81.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 80.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 80.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 79.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 76.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 75.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 74.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 72.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 71.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 68.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 61.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 57.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 172.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 172.6
FF:10158-103A5 76 years, female 172.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 136.5
Pig sample Sample description nTPM
Midbrain
nTPM: 121.9
Samples: 4

Max nTPM: 131.7
Min nTPM: 107.8
Sample A Female 131.7
Sample B Female 121.6
Sample C Male 126.3
Sample D Male 107.8
Periaqueductal gray
nTPM: 101.2
Samples: 3

Max nTPM: 116.7
Min nTPM: 87.4
Sample B Female 116.7
Sample C Male 99.6
Sample D Male 87.4
Substantia nigra
nTPM: 111.2
Samples: 4

Max nTPM: 163.4
Min nTPM: 73.6
Sample A Female 163.4
Sample B Female 109.9
Sample C Male 97.7
Sample D Male 73.6
Superior colliculi
nTPM: 136.6
Samples: 4

Max nTPM: 174.4
Min nTPM: 100.9
Sample A Female 174.4
Sample B Female 133.9
Sample C Male 137.0
Sample D Male 100.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 139.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 139.9
Samples: 4

Max nTPM: 142.9
Min nTPM: 137.2
Sample A Male 137.8
Sample B Male 137.2
Sample C Female 141.7
Sample D Female 142.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 3.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.5
70743842 Antisense, RP_050725_01_G04, Mouse strain C57BL/6J (56 days, male) 6.1
633302 Antisense, RP_040907_02_F10, Mouse strain C57BL/6J (56 days, male) 0.9

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