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BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

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No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
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Consensus:1581.9 nTPM
HPA:1581.9 nTPM
FANTOM5:1574.3 Scaled Tags Per Million
Pig:638.3 nTPM
Allen mouse:10.6 Expression energy

PONS - HPA Brain RNA-seq
Max nTPM 1581.9
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 1474.7
2301 Female, age 85, both hemispheres 1538.2
1984 Male, age 76, both hemispheres 1514.3
2090 Male, age 80, both hemispheres 1437.6
2188 Female, age 91, both hemispheres 1408.8
Dorsal cochlear nucleus
nTPM: 1581.9
2802 Male, age 74, right hemisphere 1687.7
2058 Male, age 76, both hemispheres 1625.6
2378 Male, age 80, both hemispheres 1611.1
2370 Male, age 61, both hemispheres 1546.1
2187 Female, age 91, both hemispheres 1439.2
Dorsal tegmental nucleus
nTPM: 1528.8
1936 Male, age 76, left hemisphere 1653.1
2083 Male, age 80, both hemispheres 1558.3
2326 Male, age 74, both hemispheres 1536.1
2358 Male, age 61, both hemispheres 1367.8
Dorsolateral tegmental area
nTPM: 1469.4
2141 Male, age 76, both hemispheres 1548.3
2654 Male, age 80, both hemispheres 1541.1
2751 Female, age 85, both hemispheres 1506.8
2360 Male, age 74, both hemispheres 1476.6
2337 Male, age 61, both hemispheres 1274.4
Kolliker-Fuse nucleus
nTPM: 1551.8
2315 Male, age 76, right hemisphere 1790.1
2163 Male, age 80, both hemispheres 1455.5
2793 Female, age 91, left hemisphere 1409.8
Lateral lemniscal nuclei
nTPM: 1373.8
2169 Male, age 76, both hemispheres 1451.8
2036 Male, age 80, both hemispheres 1387.4
2746 Female, age 85, left hemisphere 1357.1
2320 Female, age 91, left hemisphere 1354.1
2453 Male, age 74, right hemisphere 1318.6
Lateral parabrachial nucleus
nTPM: 1480.1
2792 Male, age 76, both hemispheres 1605.4
2139 Female, age 85, right hemisphere 1511.7
2013 Male, age 80, both hemispheres 1493.6
2790 Male, age 61, both hemispheres 1309.6
Lateral vestibular nucleus
nTPM: 1531.1
2184 Male, age 76, both hemispheres 1562.3
2311 Male, age 80, both hemispheres 1500.0
Locus coeruleus
nTPM: 1528.7
2317 Female, age 72, unknown 1630.0
2720 Male, age 74, both hemispheres 1547.5
2162 Male, age 80, both hemispheres 1542.9
1980 Male, age 76, both hemispheres 1527.7
2788 Male, age 74, unknown 1492.4
2014 Male, age 55, unknown 1488.5
2123 Female, age 91, both hemispheres 1472.0
Medial olivary nucleus
nTPM: 1526.0
2138 Female, age 91, both hemispheres 1680.2
2851 Male, age 80, both hemispheres 1510.3
1943 Male, age 61, both hemispheres 1497.3
1962 Male, age 76, both hemispheres 1416.3
Medial parabrachial nucleus
nTPM: 1452.0
2786 Male, age 76, both hemispheres 1541.4
2463 Female, age 85, right hemisphere 1535.1
2156 Male, age 61, both hemispheres 1395.1
2854 Male, age 80, both hemispheres 1394.5
2170 Female, age 91, both hemispheres 1394.3
Medial periolivary nuclei
nTPM: 1368.7
2063 Male, age 76, both hemispheres 1447.1
2791 Male, age 74, right hemisphere 1379.7
2081 Male, age 80, both hemispheres 1360.3
2458 Female, age 91, both hemispheres 1352.5
2171 Female, age 85, both hemispheres 1303.7
Motor facial nucleus
nTPM: 1400.8
2795 Female, age 91, both hemispheres 1485.1
2062 Male, age 76, both hemispheres 1474.7
2697 Female, age 85, both hemispheres 1380.5
2126 Male, age 61, both hemispheres 1371.8
2365 Male, age 74, right hemisphere 1361.6
2327 Male, age 80, both hemispheres 1331.4
Motor trigeminal nucleus
nTPM: 1390.3
2309 Male, age 76, both hemispheres 1531.1
2335 Male, age 61, both hemispheres 1376.0
2560 Male, age 74, both hemispheres 1374.6
2321 Female, age 91, both hemispheres 1350.6
2079 Male, age 80, both hemispheres 1318.9
Nuclei of the trapezoid body
nTPM: 1385.2
1983 Male, age 76, both hemispheres 1458.9
2368 Female, age 91, both hemispheres 1429.2
2166 Male, age 80, both hemispheres 1401.9
2159 Male, age 61, both hemispheres 1342.5
2735 Female, age 85, both hemispheres 1293.3
Paramedian reticular nucleus
nTPM: 1393.0
2057 Male, age 80, both hemispheres 1428.8
2052 Male, age 76, both hemispheres 1424.4
2313 Male, age 61, both hemispheres 1384.9
2050 Female, age 85, both hemispheres 1333.9
Pontine nuclei
nTPM: 1336.6
1968 Male, age 76, left hemisphere 1444.0
2115 Male, age 80, left hemisphere 1411.1
2319 Female, age 91, both hemispheres 1367.9
1863 Male, age 55, unknown 1336.0
2109 Female, age 72, unknown 1312.1
2454 Male, age 74, left hemisphere 1299.3
2787 Female, age 85, both hemispheres 1269.2
2727 Male, age 61, right hemisphere 1253.6
Pontine raphe nucleus
nTPM: 1481.9
2853 Male, age 76, midline 1590.7
2122 Female, age 85, midline 1373.1
Posteroventral cochlear nucleus
nTPM: 1491.5
2371 Male, age 61, both hemispheres 1632.7
2070 Male, age 76, both hemispheres 1481.7
2341 Male, age 80, both hemispheres 1465.2
2752 Female, age 85, both hemispheres 1455.9
2135 Female, age 91, both hemispheres 1422.1
Principal sensory trigeminal nucleus
nTPM: 1401.9
2324 Male, age 76, both hemispheres 1642.1
2158 Male, age 61, both hemispheres 1327.7
2367 Female, age 91, left hemisphere 1322.9
2008 Male, age 80, left hemisphere 1315.0
Reticular pontine nucleus, caudal
nTPM: 1383.3
2092 Male, age 76, both hemispheres 1500.5
2559 Male, age 74, both hemispheres 1363.9
2457 Female, age 91, both hemispheres 1354.9
2332 Male, age 80, right hemisphere 1314.1
Reticular pontine nucleus, oral
nTPM: 1441.3
2167 Male, age 76, both hemispheres 1597.1
1939 Male, age 80, both hemispheres 1533.2
2366 Female, age 91, both hemispheres 1421.2
2012 Female, age 85, both hemispheres 1407.6
2361 Male, age 74, both hemispheres 1247.3
Reticulotegmental nucleus
nTPM: 1466.9
2325 Male, age 76, both hemispheres 1502.2
2333 Male, age 80, both hemispheres 1460.9
2452 Male, age 74, both hemispheres 1458.2
2322 Female, age 91, both hemispheres 1446.3
Spinal trigeminal nucleus, oral
nTPM: 1475.5
1978 Male, age 76, both hemispheres 1547.1
2737 Female, age 85, both hemispheres 1454.6
2164 Male, age 80, both hemispheres 1424.9
Subcoeruleus area
nTPM: 1496.7
2451 Male, age 74, both hemispheres 1621.4
2369 Female, age 85, left hemisphere 1514.6
2323 Female, age 91, left hemisphere 1482.1
2089 Male, age 76, left hemisphere 1434.6
1958 Male, age 80, both hemispheres 1430.6
Superior olive
nTPM: 1384.7
2020 Male, age 76, both hemispheres 1493.4
2329 Male, age 80, right hemisphere 1389.3
2364 Male, age 74, right hemisphere 1367.0
2561 Female, age 91, both hemispheres 1364.8
1875 Female, age 85, both hemispheres 1309.3
Superior vestibular nucleus
nTPM: 1567.4
2061 Male, age 76, both hemispheres 1656.4
2383 Male, age 74, both hemispheres 1558.2
2015 Male, age 80, both hemispheres 1487.6
Ventral periolivary nuclei
nTPM: 1390.2
2023 Male, age 76, both hemispheres 1469.8
2165 Male, age 80, both hemispheres 1391.5
2130 Female, age 85, both hemispheres 1375.4
2794 Female, age 91, left hemisphere 1324.2
Ventrolateral tegmental area, A5 NE cell group
nTPM: 1415.2
2456 Female, age 91, both hemispheres 1446.1
2359 Male, age 61, both hemispheres 1445.8
1959 Male, age 76, both hemispheres 1432.1
2161 Male, age 80, both hemispheres 1417.1
2840 Female, age 85, both hemispheres 1411.7
2449 Male, age 74, both hemispheres 1338.2

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

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Max Scaled Tags Per Million 1574.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 1574.3
FF:10182-103D2 60 years, female 2183.5
FF:10165-103B3 76 years, female 965.1
Pons
Scaled Tags Per Million: 700.7
FF:10033-101E6 18-54 years, mixed 700.7

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
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Average nTPM 638.3
Pig sample Sample description nTPM
Pons
nTPM: 638.3
Samples: 4

Max nTPM: 740.8
Min nTPM: 516.7
Sample A Female 672.6
Sample B Female 516.7
Sample C Male 740.8
Sample D Male 623.2

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

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Max Expression energy 10.6
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 10.6
79568051 Antisense, RP_071204_02_C04, Mouse strain C57BL/6J (56 days, male) 13.0
1238 Antisense, RP_Baylor_103165, Mouse strain C57BL/6J (56 days, male) 8.3
79912570 Antisense, RP_071204_02_C04, Mouse strain C57BL/6J (56 days, male) 7.9
1237 Antisense, RP_Baylor_103165, Mouse strain C57BL/6J (56 days, male) 6.6

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.