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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:138.5 nTPM
HPA:138.5 nTPM
GTEx:72.5 nTPM
FANTOM5:38.5 Scaled Tags Per Million
Pig:53.1 nTPM
Mouse:55.7 nTPM
Allen mouse:0.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 138.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 113.1
2411 Female, age 72, unknown 118.3
1827 Male, age 72, unknown 117.4
2666 Male, age 74, left hemisphere 117.3
2828 Female, age 72, unknown 115.7
2586 Male, age 75, left hemisphere 115.0
1870 Female, age 42, unknown 113.6
2219 Male, age 76, both hemispheres 111.0
1833 Male, age 53, unknown 110.9
1830 Male, age 51, unknown 109.0
2019 Male, age 18, unknown 103.2
Dorsal raphe nucleus
nTPM: 122.6
2298 Female, age 72, unknown 130.6
2750 Male, age 76, both hemispheres 128.2
2047 Male, age 72, unknown 125.9
1828 Male, age 53, unknown 114.7
2016 Female, age 72, unknown 113.8
Inferior colliculus
nTPM: 110.5
2849 Male, age 72, unknown 113.5
1848 Female, age 42, unknown 111.0
2097 Female, age 72, unknown 110.6
1890 Male, age 53, unknown 107.1
Median raphe nucleus
nTPM: 138.5
2220 Male, age 76, midline 138.5
Pedunculopontine tegmental nucleus
nTPM: 120.9
2334 Male, age 80, both hemispheres 127.2
1921 Female, age 85, both hemispheres 119.6
2338 Male, age 61, both hemispheres 116.0
Periaquaductal grey, anterior
nTPM: 118.6
1795 Male, age 51, unknown 121.3
1947 Male, age 18, unknown 120.7
2502 Female, age 75, unknown 113.9
Periaquaductal grey, dorsal
nTPM: 116.8
2850 Male, age 76, both hemispheres 121.7
1840 Male, age 53, unknown 120.7
2464 Female, age 72, unknown 113.7
1831 Male, age 72, unknown 111.1
Periaquaductal grey, lateral
nTPM: 113.0
2053 Male, age 18, unknown 116.3
2140 Male, age 76, both hemispheres 114.3
2272 Male, age 74, both hemispheres 108.5
Pretectal area
nTPM: 116.4
2224 Female, age 72, unknown 124.2
1817 Female, age 42, unknown 122.6
1816 Male, age 51, unknown 121.9
2825 Male, age 18, unknown 120.6
2007 Male, age 72, unknown 118.7
1944 Female, age 72, unknown 118.2
1815 Male, age 53, unknown 117.3
2667 Female, age 75, unknown 115.0
2273 Male, age 74, both hemispheres 111.0
2316 Male, age 76, right hemisphere 107.0
2407 Male, age 75, both hemispheres 103.7
Red nucleus
nTPM: 107.4
2725 Female, age 75, unknown 111.1
1821 Female, age 72, unknown 110.1
2584 Male, age 75, left hemisphere 109.8
2503 Female, age 72, unknown 109.0
1954 Female, age 42, unknown 108.0
2823 Male, age 76, right hemisphere 107.8
2588 Male, age 74, left hemisphere 107.6
2227 Male, age 72, unknown 107.4
2769 Male, age 72, unknown 105.9
2785 Male, age 18, unknown 104.9
1865 Male, age 51, unknown 104.6
1904 Male, age 53, unknown 103.0
Substantia nigra
nTPM: 115.5
1941 Male, age 53, unknown 123.2
1916 Female, age 42, unknown 118.9
2665 Male, age 74, both hemispheres 118.3
1851 Male, age 51, unknown 117.8
1889 Female, age 72, unknown 117.5
2699 Male, age 18, unknown 115.7
2241 Male, age 72, unknown 115.1
2583 Male, age 75, right hemisphere 111.0
2590 Female, age 75, unknown 110.9
2409 Female, age 72, unknown 106.2
Superior colliculus
nTPM: 112.1
2261 Male, age 18, unknown 117.1
2668 Female, age 75, unknown 116.8
1796 Male, age 53, unknown 115.9
1839 Male, age 51, unknown 113.1
2087 Female, age 72, unknown 112.8
2587 Male, age 74, left hemisphere 112.6
2664 Male, age 75, both hemispheres 109.6
1895 Male, age 76, right hemisphere 109.2
1913 Female, age 42, unknown 107.7
1995 Male, age 72, unknown 106.5
Ventral tegmental area
nTPM: 117.3
2021 Male, age 53, unknown 119.9
2218 Male, age 76, both hemispheres 119.8
2410 Female, age 72, unknown 118.8
1915 Female, age 42, unknown 117.6
2223 Female, age 72, unknown 114.1
1942 Male, age 51, unknown 113.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 72.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 72.5
Samples: 139

Max nTPM: 175.8
Min nTPM: 36.0
Std nTPM: 21.8
Median nTPM: 68.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 175.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 168.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 128.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 124.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 114.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 112.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 111.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 108.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 105.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 104.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 102.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 99.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 99.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 98.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 96.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 96.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 95.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 94.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 93.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 93.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 92.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 92.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 90.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 90.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 89.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 88.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 88.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 87.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 87.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 85.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 85.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 84.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 84.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 83.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 83.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 82.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 80.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 79.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 79.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 79.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 79.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 79.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 79.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 79.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 78.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 78.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 78.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 77.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 76.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 76.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 75.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 75.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 74.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 74.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 74.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 73.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 73.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 72.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 72.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 70.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 70.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 70.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 70.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 70.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 69.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 69.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 69.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 69.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 69.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 68.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 68.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 68.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 68.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 68.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 68.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 67.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 67.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 67.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 66.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 66.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 66.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 66.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 66.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 66.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 65.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 65.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 64.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 64.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 63.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 62.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 62.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 62.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 62.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 62.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 62.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 61.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 60.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 60.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 60.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 59.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 59.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 59.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 59.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 58.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 58.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 57.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 57.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 56.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 56.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 56.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 55.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 55.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 54.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 54.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 54.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 53.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 53.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 51.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 51.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 50.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 50.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 50.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 49.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 48.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 48.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 48.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 47.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 47.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 47.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 46.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 46.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 46.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 45.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 44.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 43.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 42.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 39.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 38.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 36.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 38.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 38.5
FF:10158-103A5 76 years, female 38.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 53.1
Pig sample Sample description nTPM
Midbrain
nTPM: 49.7
Samples: 4

Max nTPM: 59.8
Min nTPM: 41.4
Sample A Female 59.8
Sample B Female 51.5
Sample C Male 46.0
Sample D Male 41.4
Periaqueductal gray
nTPM: 48.2
Samples: 3

Max nTPM: 62.7
Min nTPM: 35.5
Sample B Female 46.4
Sample C Male 62.7
Sample D Male 35.5
Substantia nigra
nTPM: 53.1
Samples: 4

Max nTPM: 77.4
Min nTPM: 27.1
Sample A Female 77.4
Sample B Female 49.6
Sample C Male 58.2
Sample D Male 27.1
Superior colliculi
nTPM: 43.3
Samples: 4

Max nTPM: 59.0
Min nTPM: 32.5
Sample A Female 59.0
Sample B Female 46.2
Sample C Male 35.4
Sample D Male 32.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 55.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 55.7
Samples: 4

Max nTPM: 61.3
Min nTPM: 44.1
Sample A Male 61.3
Sample B Male 60.5
Sample C Female 44.1
Sample D Female 56.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.1
1803 Antisense, RP_040604_01_B05, Mouse strain C57BL/6J (56 days, male) 0.1
1802 Antisense, RP_040604_01_B05, Mouse strain C57BL/6J (56 days, male) 0.1

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