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CPLX4
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BRAIN RETINA Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Eye
Retina
RETINA - Expression summary
Protein expression
Retinai

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
h
m
l
n
Ganglion cells : Not detected
Inner nuclear layer: Not detected
Inner plexiform layer: Not detected
Limiting membrane: Not detected
Nerve fiber layer: High
Outer plexiform layer: Not detected
Photoreceptor cells: Not detected
Pigment epithelial cells: Not detected
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:314.9 nTPM
GTEx:314.9 nTPM
FANTOM5:104.9 Scaled Tags Per Million
Pig:552.9 nTPM
Mouse:582.3 nTPM

RETINA - Extended tissue profilei

For selected proteins extended tissue profiling is performed in addition to standard tissue microarrays. The section below contains results from the extended profiling.

, antibody HPA047627
Pigment epithelial cells Not detected
Photoreceptor cells Low
Limiting membrane Not detected
Outer plexiform layer High
Inner nuclear layer Not detected
Inner plexiform layer High
Ganglion cells Not detected
Nerve fiber layer Not detected

RETINA - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 314.9
GTEx sample id Sample description nTPM
Retina
Average nTPM: 314.9
Samples: 105

Max nTPM: 494.5
Min nTPM: 144.1
Std nTPM: 63.2
Median nTPM:
415_1 77 years, female 494.5
490_1 67 years, female 456.5
246_1 77 years, male 453.5
414_1 84 years, female 447.2
413_1 59 years, female 447.0
466_1 57 years, female 432.9
35_1 74 years, female 426.6
217_1 76 years, male 423.6
162_1 79 years, female 413.1
126_1 63 years, male 403.5
324_1 76 years, male 399.2
149_1 88 years, male 393.7
43_1 64 years, female 387.4
229_1 69 years, female 387.0
468_1 89 years, male 379.5
153_1 70 years, female 377.6
375_1 74 years, female 376.5
237_1 82 years, male 368.5
315_1 62 years, female 367.4
377_1 82 years, female 363.3
251_1 78 years, male 361.8
6_1 73 years, female 360.3
81_1 67 years, male 359.7
447_1 81 years, male 357.8
32_1 67 years, male 356.7
265_1 87 years, male 352.8
319_1 81 years, male 352.0
389_1 86 years, female 349.6
518_1 75 years, female 347.4
316_1 62 years, male 347.3
142_1 61 years, female 346.2
405_1 91 years, male 341.7
396_1 62 years, male 336.4
254_1 77 years, female 335.4
17_1 71 years, male 335.3
139_1 64 years, female 334.8
425_1 59 years, female 334.6
526_1 61 years, male 332.6
266_1 85 years, male 332.4
491_1 89 years, female 330.2
386_1 76 years, male 329.5
189_1 76 years, male 329.3
115_1 83 years, male 326.2
9_1 66 years, female 325.4
117_1 61 years, male 325.4
322_1 76 years, male 325.1
18_1 88 years, male 320.8
145_1 84 years, male 319.0
172_1 72 years, female 318.0
335_1 73 years, female 315.9
503_1 68 years, male 314.4
379_1 60 years, male 313.9
384_1 83 years, male 312.0
89_1 63 years, male 308.4
480_1 63 years, male 307.4
318_1 68 years, male 306.8
352_1 62 years, male 305.0
376_1 75 years, female 304.2
501_1 88 years, male 304.0
311_1 78 years, male 303.5
137_1 83 years, male 301.7
404_1 82 years, female 301.7
313_1 79 years, female 300.3
499_1 55 years, female 297.7
347_1 72 years, male 297.5
243_1 75 years, male 296.1
495_1 57 years, female 295.7
307_1 66 years, female 295.5
321_1 62 years, female 292.1
292_1 71 years, male 288.5
2_1 77 years, female 285.8
177_1 74 years, male 284.7
406_1 79 years, male 279.5
348_1 84 years, male 278.1
218_1 71 years, female 274.5
119_1 70 years, female 272.6
517_1 88 years, male 270.9
288_1 66 years, female 270.1
355_1 70 years, female 268.0
354_1 81 years, female 266.9
99_1 64 years, male 266.5
394_1 75 years, female 265.4
4_1 88 years, female 265.0
293_1 68 years, female 264.6
350_1 84 years, female 262.5
286_1 68 years, female 261.6
42_1 85 years, male 261.4
120_1 70 years, female 257.2
320_1 89 years, female 254.2
291_1 76 years, male 253.1
173_1 67 years, male 250.7
314_1 67 years, male 250.0
109_1 81 years, female 244.6
351_1 91 years, male 240.0
317_1 60 years, male 234.5
264_1 73 years, female 233.6
356_1 87 years, female 233.4
349_1 83 years, male 231.8
163_1 78 years, male 228.2
353_1 82 years, female 223.4
41_1 94 years, female 220.9
295_1 61 years, female 195.1
506_1 65 years, male 194.1
452_1 88 years, female 190.2
308_1 70 years, female 144.1
Show allShow less

RETINA - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 104.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Retina
Scaled Tags Per Million: 104.9
FF:10030-101E3 24-65 years, mixed 104.9

RETINA - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 552.9
Pig sample Sample description nTPM
Retina
nTPM: 552.9
Samples: 4

Max nTPM: 646.6
Min nTPM: 459.6
Sample A Female 546.4
Sample B Female 459.6
Sample C Male 646.6
Sample D Male 559.0

RETINA - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 582.3
Mouse sample Sample description nTPM
Retina
nTPM: 582.3
Samples: 4

Max nTPM: 591.6
Min nTPM: 575.6
Sample A Male 575.6
Sample B Male 583.3
Sample C Female 578.8
Sample D Female 591.6

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.