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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:42.5 nTPM
HPA:42.5 nTPM
GTEx:83.3 nTPM
FANTOM5:21.0 Scaled Tags Per Million
Pig:65.1 nTPM
Mouse:175.8 nTPM
Allen mouse:4.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 42.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 39.1
2219 Male, age 76, both hemispheres 40.7
1870 Female, age 42, unknown 40.5
2411 Female, age 72, unknown 40.1
2019 Male, age 18, unknown 39.5
1830 Male, age 51, unknown 39.4
2828 Female, age 72, unknown 39.2
1833 Male, age 53, unknown 38.7
2586 Male, age 75, left hemisphere 38.2
2666 Male, age 74, left hemisphere 37.8
1827 Male, age 72, unknown 36.6
Dorsal raphe nucleus
nTPM: 40.2
2750 Male, age 76, both hemispheres 43.7
1828 Male, age 53, unknown 40.3
2298 Female, age 72, unknown 40.0
2047 Male, age 72, unknown 39.0
2016 Female, age 72, unknown 38.3
Inferior colliculus
nTPM: 39.4
2097 Female, age 72, unknown 41.0
1848 Female, age 42, unknown 39.9
2849 Male, age 72, unknown 38.5
1890 Male, age 53, unknown 38.1
Median raphe nucleus
nTPM: 42.5
2220 Male, age 76, midline 42.5
Pedunculopontine tegmental nucleus
nTPM: 39.8
2334 Male, age 80, both hemispheres 41.1
1921 Female, age 85, both hemispheres 40.7
2338 Male, age 61, both hemispheres 37.6
Periaquaductal grey, anterior
nTPM: 38.8
2502 Female, age 75, unknown 40.1
1947 Male, age 18, unknown 38.8
1795 Male, age 51, unknown 37.5
Periaquaductal grey, dorsal
nTPM: 38.9
2850 Male, age 76, both hemispheres 39.8
1840 Male, age 53, unknown 39.6
2464 Female, age 72, unknown 38.5
1831 Male, age 72, unknown 37.6
Periaquaductal grey, lateral
nTPM: 39.2
2272 Male, age 74, both hemispheres 41.0
2053 Male, age 18, unknown 39.8
2140 Male, age 76, both hemispheres 36.8
Pretectal area
nTPM: 39.6
2224 Female, age 72, unknown 42.0
1815 Male, age 53, unknown 41.7
2667 Female, age 75, unknown 41.5
1817 Female, age 42, unknown 40.9
2316 Male, age 76, right hemisphere 40.4
1816 Male, age 51, unknown 40.0
2007 Male, age 72, unknown 39.6
2273 Male, age 74, both hemispheres 39.3
2825 Male, age 18, unknown 38.2
2407 Male, age 75, both hemispheres 36.7
1944 Female, age 72, unknown 35.2
Red nucleus
nTPM: 40.7
1821 Female, age 72, unknown 43.4
2823 Male, age 76, right hemisphere 42.9
2503 Female, age 72, unknown 41.7
2227 Male, age 72, unknown 41.5
1904 Male, age 53, unknown 41.4
2769 Male, age 72, unknown 41.4
1954 Female, age 42, unknown 41.2
2785 Male, age 18, unknown 40.7
1865 Male, age 51, unknown 40.5
2725 Female, age 75, unknown 39.8
2588 Male, age 74, left hemisphere 38.2
2584 Male, age 75, left hemisphere 35.7
Substantia nigra
nTPM: 39.2
2241 Male, age 72, unknown 43.4
1916 Female, age 42, unknown 42.8
1889 Female, age 72, unknown 40.8
1851 Male, age 51, unknown 40.7
2665 Male, age 74, both hemispheres 39.6
2699 Male, age 18, unknown 39.6
1941 Male, age 53, unknown 36.8
2590 Female, age 75, unknown 36.8
2583 Male, age 75, right hemisphere 36.0
2409 Female, age 72, unknown 35.4
Superior colliculus
nTPM: 39.3
1913 Female, age 42, unknown 41.9
2587 Male, age 74, left hemisphere 39.8
1995 Male, age 72, unknown 39.6
2087 Female, age 72, unknown 39.4
1895 Male, age 76, right hemisphere 39.1
2668 Female, age 75, unknown 39.1
1839 Male, age 51, unknown 39.0
2261 Male, age 18, unknown 38.6
1796 Male, age 53, unknown 38.5
2664 Male, age 75, both hemispheres 38.3
Ventral tegmental area
nTPM: 40.3
2218 Male, age 76, both hemispheres 42.0
2021 Male, age 53, unknown 41.4
1915 Female, age 42, unknown 40.8
2223 Female, age 72, unknown 39.2
2410 Female, age 72, unknown 39.2
1942 Male, age 51, unknown 39.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 83.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 83.3
Samples: 139

Max nTPM: 159.8
Min nTPM: 43.8
Std nTPM: 18.7
Median nTPM: 81.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 159.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 155.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 139.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 134.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 120.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 118.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 118.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 116.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 112.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 109.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 108.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 107.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 105.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 104.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 103.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 103.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 101.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 101.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 100.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 100.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 99.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 98.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 98.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 98.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 97.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 97.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 96.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 95.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 94.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 94.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 94.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 94.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 93.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 93.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 93.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 92.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 91.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 91.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 91.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 90.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 89.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 89.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 89.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 88.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 88.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 88.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 88.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 88.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 87.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 86.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 86.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 86.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 85.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 85.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 85.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 85.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 84.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 84.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 84.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 84.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 84.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 83.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 83.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 82.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 82.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 82.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 81.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 81.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 81.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 81.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 80.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 80.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 80.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 79.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 79.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 79.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 79.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 78.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 78.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 78.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 78.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 78.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 78.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 77.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 77.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 77.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 77.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 76.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 76.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 76.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 76.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 75.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 75.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 74.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 74.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 74.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 73.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 73.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 72.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 72.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 72.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 71.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 71.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 71.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 70.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 70.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 69.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 68.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 68.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 68.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 68.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 68.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 67.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 67.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 67.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 67.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 66.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 66.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 66.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 66.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 65.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 65.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 65.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 64.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 64.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 64.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 63.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 62.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 62.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 61.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 60.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 58.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 58.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 57.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 56.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 53.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 47.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 44.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 43.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 21.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 21.0
FF:10158-103A5 76 years, female 21.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 65.1
Pig sample Sample description nTPM
Midbrain
nTPM: 62.0
Samples: 4

Max nTPM: 76.9
Min nTPM: 46.9
Sample A Female 76.9
Sample B Female 65.7
Sample C Male 58.3
Sample D Male 46.9
Periaqueductal gray
nTPM: 54.5
Samples: 3

Max nTPM: 61.4
Min nTPM: 46.2
Sample B Female 55.9
Sample C Male 61.4
Sample D Male 46.2
Substantia nigra
nTPM: 63.9
Samples: 4

Max nTPM: 82.0
Min nTPM: 51.1
Sample A Female 82.0
Sample B Female 55.8
Sample C Male 66.5
Sample D Male 51.1
Superior colliculi
nTPM: 65.2
Samples: 4

Max nTPM: 78.4
Min nTPM: 58.9
Sample A Female 78.4
Sample B Female 58.9
Sample C Male 64.4
Sample D Male 58.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 175.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 175.8
Samples: 4

Max nTPM: 185.3
Min nTPM: 166.6
Sample A Male 178.5
Sample B Male 166.6
Sample C Female 172.9
Sample D Female 185.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 4.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.8
69783071 Antisense, RP_050505_04_C10, Mouse strain C57BL/6J (56 days, male) 4.8

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