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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:327.1 nTPM
HPA:327.1 nTPM
GTEx:174.2 nTPM
FANTOM5:970.7 Scaled Tags Per Million
Pig:291.0 nTPM
Mouse:133.8 nTPM
Allen mouse:15.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 327.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 279.2
2828 Female, age 72, unknown 336.3
1870 Female, age 42, unknown 335.8
2411 Female, age 72, unknown 315.8
1833 Male, age 53, unknown 310.1
1830 Male, age 51, unknown 295.4
2586 Male, age 75, left hemisphere 291.0
2019 Male, age 18, unknown 271.3
1827 Male, age 72, unknown 238.9
2219 Male, age 76, both hemispheres 219.6
2666 Male, age 74, left hemisphere 177.9
Dorsal raphe nucleus
nTPM: 257.3
2750 Male, age 76, both hemispheres 318.8
2016 Female, age 72, unknown 280.0
1828 Male, age 53, unknown 240.7
2298 Female, age 72, unknown 232.7
2047 Male, age 72, unknown 214.5
Inferior colliculus
nTPM: 230.1
2097 Female, age 72, unknown 243.2
1848 Female, age 42, unknown 241.2
1890 Male, age 53, unknown 221.2
2849 Male, age 72, unknown 214.8
Median raphe nucleus
nTPM: 186.7
2220 Male, age 76, midline 186.7
Pedunculopontine tegmental nucleus
nTPM: 214.4
1921 Female, age 85, both hemispheres 244.9
2334 Male, age 80, both hemispheres 234.0
2338 Male, age 61, both hemispheres 164.2
Periaquaductal grey, anterior
nTPM: 238.6
2502 Female, age 75, unknown 288.3
1795 Male, age 51, unknown 224.4
1947 Male, age 18, unknown 203.2
Periaquaductal grey, dorsal
nTPM: 206.9
2464 Female, age 72, unknown 243.8
1831 Male, age 72, unknown 219.8
1840 Male, age 53, unknown 191.4
2850 Male, age 76, both hemispheres 172.8
Periaquaductal grey, lateral
nTPM: 224.2
2053 Male, age 18, unknown 271.6
2140 Male, age 76, both hemispheres 204.0
2272 Male, age 74, both hemispheres 196.9
Pretectal area
nTPM: 244.9
2667 Female, age 75, unknown 309.6
2316 Male, age 76, right hemisphere 307.6
2273 Male, age 74, both hemispheres 276.6
1815 Male, age 53, unknown 266.6
2407 Male, age 75, both hemispheres 248.3
1817 Female, age 42, unknown 236.4
2825 Male, age 18, unknown 232.5
2224 Female, age 72, unknown 221.4
1944 Female, age 72, unknown 216.7
2007 Male, age 72, unknown 195.9
1816 Male, age 51, unknown 182.7
Red nucleus
nTPM: 327.1
1904 Male, age 53, unknown 387.8
2227 Male, age 72, unknown 382.7
1821 Female, age 72, unknown 379.4
2769 Male, age 72, unknown 379.3
2503 Female, age 72, unknown 359.3
2823 Male, age 76, right hemisphere 354.5
1954 Female, age 42, unknown 350.6
1865 Male, age 51, unknown 347.3
2785 Male, age 18, unknown 336.3
2588 Male, age 74, left hemisphere 251.7
2725 Female, age 75, unknown 215.6
2584 Male, age 75, left hemisphere 180.1
Substantia nigra
nTPM: 217.7
1851 Male, age 51, unknown 268.8
2699 Male, age 18, unknown 249.4
2409 Female, age 72, unknown 231.4
1889 Female, age 72, unknown 227.7
2583 Male, age 75, right hemisphere 225.0
2590 Female, age 75, unknown 220.1
1916 Female, age 42, unknown 218.0
1941 Male, age 53, unknown 195.1
2241 Male, age 72, unknown 175.5
2665 Male, age 74, both hemispheres 165.9
Superior colliculus
nTPM: 286.5
1995 Male, age 72, unknown 399.7
1913 Female, age 42, unknown 391.7
2664 Male, age 75, both hemispheres 295.9
1796 Male, age 53, unknown 268.8
1839 Male, age 51, unknown 268.0
1895 Male, age 76, right hemisphere 265.0
2668 Female, age 75, unknown 262.1
2587 Male, age 74, left hemisphere 249.5
2087 Female, age 72, unknown 232.6
2261 Male, age 18, unknown 231.6
Ventral tegmental area
nTPM: 245.1
2410 Female, age 72, unknown 311.0
1915 Female, age 42, unknown 251.8
2223 Female, age 72, unknown 245.6
1942 Male, age 51, unknown 242.8
2021 Male, age 53, unknown 217.8
2218 Male, age 76, both hemispheres 201.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 174.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 174.2
Samples: 139

Max nTPM: 619.2
Min nTPM: 59.8
Std nTPM: 77.3
Median nTPM: 154.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 619.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 463.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 457.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 381.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 359.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 349.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 320.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 316.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 284.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 273.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 261.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 256.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 250.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 246.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 240.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 239.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 237.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 234.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 233.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 231.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 229.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 228.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 227.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 226.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 224.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 223.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 220.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 216.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 213.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 212.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 210.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 209.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 203.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 203.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 202.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 202.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 200.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 198.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 197.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 197.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 194.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 192.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 191.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 188.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 188.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 188.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 186.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 186.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 182.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 181.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 176.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 175.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 175.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 174.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 172.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 172.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 172.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 172.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 171.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 171.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 171.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 168.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 166.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 165.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 165.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 162.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 158.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 158.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 154.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 154.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 154.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 153.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 153.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 150.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 150.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 149.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 149.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 148.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 147.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 147.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 147.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 146.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 143.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 143.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 142.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 142.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 139.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 138.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 137.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 136.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 136.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 134.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 134.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 134.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 133.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 133.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 131.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 130.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 129.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 129.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 128.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 128.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 126.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 126.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 126.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 125.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 123.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 122.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 121.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 121.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 121.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 121.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 118.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 117.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 115.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 115.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 113.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 108.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 108.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 107.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 107.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 107.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 107.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 107.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 106.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 102.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 102.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 101.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 101.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 99.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 98.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 96.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 96.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 92.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 89.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 82.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 79.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 76.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 59.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 970.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 970.7
FF:10158-103A5 76 years, female 970.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 291.0
Pig sample Sample description nTPM
Midbrain
nTPM: 291.0
Samples: 4

Max nTPM: 396.8
Min nTPM: 226.6
Sample A Female 396.8
Sample B Female 311.4
Sample C Male 229.1
Sample D Male 226.6
Periaqueductal gray
nTPM: 238.4
Samples: 3

Max nTPM: 284.3
Min nTPM: 205.9
Sample B Female 284.3
Sample C Male 205.9
Sample D Male 225.1
Substantia nigra
nTPM: 290.7
Samples: 4

Max nTPM: 397.0
Min nTPM: 214.6
Sample A Female 298.2
Sample B Female 214.6
Sample C Male 253.0
Sample D Male 397.0
Superior colliculi
nTPM: 275.8
Samples: 4

Max nTPM: 335.4
Min nTPM: 160.1
Sample A Female 335.4
Sample B Female 160.1
Sample C Male 274.8
Sample D Male 332.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 133.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 133.8
Samples: 4

Max nTPM: 136.5
Min nTPM: 131.5
Sample A Male 136.5
Sample B Male 131.5
Sample C Female 133.4
Sample D Female 133.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 15.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 15.3
71836881 Antisense, RP_051017_02_E11, Mouse strain C57BL/6J (56 days, male) 19.0
68633038 Antisense, RP_050125_02_C10, Mouse strain C57BL/6J (56 days, male) 11.7

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