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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:66.5 nTPM
HPA:66.5 nTPM
GTEx:334.8 nTPM
FANTOM5:154.1 Scaled Tags Per Million
Pig:109.8 nTPM
Mouse:126.1 nTPM
Allen mouse:1.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 66.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 64.2
2586 Male, age 75, left hemisphere 85.4
2828 Female, age 72, unknown 76.8
2411 Female, age 72, unknown 68.9
1870 Female, age 42, unknown 64.4
1827 Male, age 72, unknown 63.6
1830 Male, age 51, unknown 60.6
1833 Male, age 53, unknown 59.4
2019 Male, age 18, unknown 57.4
2666 Male, age 74, left hemisphere 53.4
2219 Male, age 76, both hemispheres 51.7
Dorsal raphe nucleus
nTPM: 64.9
2298 Female, age 72, unknown 66.7
2750 Male, age 76, both hemispheres 66.1
2047 Male, age 72, unknown 65.4
1828 Male, age 53, unknown 63.7
2016 Female, age 72, unknown 62.6
Inferior colliculus
nTPM: 59.8
2097 Female, age 72, unknown 64.1
1848 Female, age 42, unknown 60.7
1890 Male, age 53, unknown 59.5
2849 Male, age 72, unknown 55.0
Median raphe nucleus
nTPM: 51.8
2220 Male, age 76, midline 51.8
Pedunculopontine tegmental nucleus
nTPM: 53.5
1921 Female, age 85, both hemispheres 59.7
2334 Male, age 80, both hemispheres 57.4
2338 Male, age 61, both hemispheres 43.4
Periaquaductal grey, anterior
nTPM: 61.9
1947 Male, age 18, unknown 63.9
2502 Female, age 75, unknown 61.2
1795 Male, age 51, unknown 60.7
Periaquaductal grey, dorsal
nTPM: 56.5
1840 Male, age 53, unknown 64.2
2464 Female, age 72, unknown 57.1
2850 Male, age 76, both hemispheres 54.0
1831 Male, age 72, unknown 50.7
Periaquaductal grey, lateral
nTPM: 55.0
2053 Male, age 18, unknown 65.7
2140 Male, age 76, both hemispheres 55.1
2272 Male, age 74, both hemispheres 44.1
Pretectal area
nTPM: 61.0
2407 Male, age 75, both hemispheres 73.7
2316 Male, age 76, right hemisphere 65.4
2667 Female, age 75, unknown 64.7
2825 Male, age 18, unknown 64.5
1817 Female, age 42, unknown 60.4
2224 Female, age 72, unknown 60.4
1816 Male, age 51, unknown 59.2
1815 Male, age 53, unknown 59.1
2273 Male, age 74, both hemispheres 57.8
2007 Male, age 72, unknown 54.2
1944 Female, age 72, unknown 51.4
Red nucleus
nTPM: 66.5
2769 Male, age 72, unknown 74.7
1904 Male, age 53, unknown 74.2
2227 Male, age 72, unknown 74.2
1954 Female, age 42, unknown 71.3
1821 Female, age 72, unknown 70.3
2503 Female, age 72, unknown 68.7
2588 Male, age 74, left hemisphere 67.9
1865 Male, age 51, unknown 65.6
2823 Male, age 76, right hemisphere 63.5
2725 Female, age 75, unknown 60.1
2584 Male, age 75, left hemisphere 54.4
2785 Male, age 18, unknown 53.5
Substantia nigra
nTPM: 64.3
2583 Male, age 75, right hemisphere 73.9
1851 Male, age 51, unknown 69.5
1916 Female, age 42, unknown 67.8
2699 Male, age 18, unknown 65.3
2241 Male, age 72, unknown 64.9
2590 Female, age 75, unknown 64.5
2665 Male, age 74, both hemispheres 62.8
1889 Female, age 72, unknown 61.4
2409 Female, age 72, unknown 60.1
1941 Male, age 53, unknown 52.6
Superior colliculus
nTPM: 63.4
2664 Male, age 75, both hemispheres 88.9
1995 Male, age 72, unknown 66.7
2668 Female, age 75, unknown 64.1
1796 Male, age 53, unknown 62.3
2087 Female, age 72, unknown 60.8
2261 Male, age 18, unknown 60.8
2587 Male, age 74, left hemisphere 58.8
1839 Male, age 51, unknown 58.7
1895 Male, age 76, right hemisphere 56.9
1913 Female, age 42, unknown 56.0
Ventral tegmental area
nTPM: 60.1
1915 Female, age 42, unknown 65.5
1942 Male, age 51, unknown 63.6
2021 Male, age 53, unknown 63.5
2410 Female, age 72, unknown 59.1
2218 Male, age 76, both hemispheres 56.7
2223 Female, age 72, unknown 52.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 334.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 334.8
Samples: 139

Max nTPM: 1079.7
Min nTPM: 41.1
Std nTPM: 175.7
Median nTPM: 294.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1079.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 953.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 912.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 840.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 766.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 749.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 721.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 676.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 656.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 626.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 596.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 574.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 573.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 559.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 557.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 527.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 518.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 508.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 506.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 497.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 492.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 487.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 476.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 468.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 463.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 445.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 444.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 431.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 430.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 428.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 418.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 412.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 406.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 404.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 402.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 400.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 388.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 386.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 383.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 378.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 375.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 372.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 370.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 369.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 362.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 362.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 361.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 359.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 357.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 354.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 344.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 343.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 343.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 341.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 340.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 323.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 315.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 314.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 313.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 312.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 311.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 311.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 305.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 303.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 303.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 300.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 298.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 297.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 294.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 294.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 293.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 293.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 293.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 292.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 289.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 288.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 286.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 277.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 276.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 272.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 272.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 272.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 271.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 270.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 269.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 262.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 260.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 256.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 251.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 247.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 246.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 245.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 245.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 245.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 240.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 239.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 237.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 237.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 236.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 234.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 234.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 229.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 226.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 225.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 225.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 225.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 221.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 220.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 218.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 214.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 209.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 209.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 207.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 199.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 198.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 192.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 190.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 189.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 187.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 187.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 185.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 184.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 183.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 180.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 171.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 167.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 162.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 153.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 133.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 132.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 131.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 124.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 106.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 100.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 99.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 93.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 84.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 66.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 41.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 154.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 154.1
FF:10158-103A5 76 years, female 154.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 109.8
Pig sample Sample description nTPM
Midbrain
nTPM: 108.7
Samples: 4

Max nTPM: 124.2
Min nTPM: 97.0
Sample A Female 114.2
Sample B Female 124.2
Sample C Male 99.3
Sample D Male 97.0
Periaqueductal gray
nTPM: 102.4
Samples: 3

Max nTPM: 112.4
Min nTPM: 87.4
Sample B Female 112.4
Sample C Male 107.5
Sample D Male 87.4
Substantia nigra
nTPM: 109.8
Samples: 4

Max nTPM: 139.6
Min nTPM: 77.2
Sample A Female 105.6
Sample B Female 77.2
Sample C Male 116.9
Sample D Male 139.6
Superior colliculi
nTPM: 89.1
Samples: 4

Max nTPM: 109.5
Min nTPM: 42.8
Sample A Female 102.8
Sample B Female 42.8
Sample C Male 101.3
Sample D Male 109.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 126.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 126.1
Samples: 4

Max nTPM: 138.8
Min nTPM: 109.9
Sample A Male 138.8
Sample B Male 109.9
Sample C Female 128.4
Sample D Female 127.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 1.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.7
70919830 Antisense, RP_050713_02_B05, Mouse strain C57BL/6J (56 days, male) 1.7

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