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PPP1R14A
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  • PPP1R14A
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:322.9 nTPM
HPA:322.9 nTPM
GTEx:343.3 nTPM
FANTOM5:283.6 Scaled Tags Per Million
Pig:305.8 nTPM
Mouse:23.7 nTPM
Allen mouse:0.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 322.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 236.0
1830 Male, age 51, unknown 295.2
1833 Male, age 53, unknown 291.7
2411 Female, age 72, unknown 274.5
1870 Female, age 42, unknown 265.6
2019 Male, age 18, unknown 252.6
2828 Female, age 72, unknown 238.5
2666 Male, age 74, left hemisphere 202.1
2586 Male, age 75, left hemisphere 192.6
2219 Male, age 76, both hemispheres 181.4
1827 Male, age 72, unknown 165.9
Dorsal raphe nucleus
nTPM: 177.5
2750 Male, age 76, both hemispheres 308.4
2016 Female, age 72, unknown 178.6
1828 Male, age 53, unknown 166.8
2047 Male, age 72, unknown 121.6
2298 Female, age 72, unknown 112.2
Inferior colliculus
nTPM: 168.1
2849 Male, age 72, unknown 194.9
1848 Female, age 42, unknown 172.5
1890 Male, age 53, unknown 170.0
2097 Female, age 72, unknown 135.0
Median raphe nucleus
nTPM: 162.5
2220 Male, age 76, midline 162.5
Pedunculopontine tegmental nucleus
nTPM: 250.6
2338 Male, age 61, both hemispheres 304.0
2334 Male, age 80, both hemispheres 258.6
1921 Female, age 85, both hemispheres 189.0
Periaquaductal grey, anterior
nTPM: 128.0
1947 Male, age 18, unknown 135.4
1795 Male, age 51, unknown 125.9
2502 Female, age 75, unknown 122.6
Periaquaductal grey, dorsal
nTPM: 123.4
2464 Female, age 72, unknown 172.1
1831 Male, age 72, unknown 134.0
2850 Male, age 76, both hemispheres 96.4
1840 Male, age 53, unknown 91.1
Periaquaductal grey, lateral
nTPM: 128.6
2272 Male, age 74, both hemispheres 158.8
2053 Male, age 18, unknown 137.4
2140 Male, age 76, both hemispheres 89.5
Pretectal area
nTPM: 155.8
1815 Male, age 53, unknown 210.9
2316 Male, age 76, right hemisphere 207.3
1817 Female, age 42, unknown 185.9
2407 Male, age 75, both hemispheres 175.5
2007 Male, age 72, unknown 174.0
2825 Male, age 18, unknown 169.6
2273 Male, age 74, both hemispheres 133.7
2224 Female, age 72, unknown 125.0
1944 Female, age 72, unknown 114.8
1816 Male, age 51, unknown 109.3
2667 Female, age 75, unknown 108.1
Red nucleus
nTPM: 322.9
2823 Male, age 76, right hemisphere 413.0
2769 Male, age 72, unknown 358.0
1904 Male, age 53, unknown 356.0
1821 Female, age 72, unknown 351.9
2227 Male, age 72, unknown 348.3
1865 Male, age 51, unknown 338.9
2503 Female, age 72, unknown 318.3
1954 Female, age 42, unknown 313.1
2785 Male, age 18, unknown 303.1
2588 Male, age 74, left hemisphere 281.1
2725 Female, age 75, unknown 276.0
2584 Male, age 75, left hemisphere 217.2
Substantia nigra
nTPM: 168.0
2583 Male, age 75, right hemisphere 221.4
2590 Female, age 75, unknown 212.5
1889 Female, age 72, unknown 195.0
1851 Male, age 51, unknown 184.0
2699 Male, age 18, unknown 174.8
2665 Male, age 74, both hemispheres 146.7
1941 Male, age 53, unknown 144.9
2409 Female, age 72, unknown 143.5
1916 Female, age 42, unknown 142.0
2241 Male, age 72, unknown 115.6
Superior colliculus
nTPM: 200.1
1995 Male, age 72, unknown 281.1
2668 Female, age 75, unknown 259.2
1913 Female, age 42, unknown 251.1
1895 Male, age 76, right hemisphere 230.0
2587 Male, age 74, left hemisphere 216.6
1839 Male, age 51, unknown 208.0
1796 Male, age 53, unknown 165.1
2664 Male, age 75, both hemispheres 134.8
2087 Female, age 72, unknown 130.4
2261 Male, age 18, unknown 124.8
Ventral tegmental area
nTPM: 193.7
2223 Female, age 72, unknown 259.5
2410 Female, age 72, unknown 214.1
2218 Male, age 76, both hemispheres 179.9
1942 Male, age 51, unknown 171.3
2021 Male, age 53, unknown 171.0
1915 Female, age 42, unknown 166.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 343.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 343.3
Samples: 139

Max nTPM: 1391.6
Min nTPM: 63.1
Std nTPM: 232.5
Median nTPM: 269.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1391.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1372.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1272.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1140.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1109.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 721.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 701.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 666.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 659.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 655.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 619.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 609.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 608.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 590.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 568.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 563.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 563.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 536.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 533.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 530.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 526.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 517.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 515.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 510.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 493.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 488.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 476.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 462.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 457.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 456.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 442.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 442.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 440.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 439.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 437.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 415.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 411.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 406.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 404.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 402.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 400.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 395.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 393.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 376.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 367.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 366.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 362.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 358.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 358.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 358.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 355.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 354.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 350.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 344.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 343.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 340.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 339.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 324.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 322.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 311.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 310.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 307.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 301.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 300.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 298.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 297.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 294.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 292.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 282.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 269.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 267.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 266.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 265.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 264.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 262.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 257.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 256.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 256.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 254.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 254.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 251.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 250.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 245.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 245.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 239.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 235.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 234.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 233.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 228.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 228.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 226.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 220.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 218.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 216.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 211.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 211.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 209.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 209.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 206.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 205.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 204.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 203.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 202.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 201.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 201.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 196.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 194.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 193.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 190.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 189.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 186.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 184.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 182.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 173.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 173.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 173.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 171.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 163.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 160.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 160.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 159.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 156.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 154.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 147.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 141.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 141.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 141.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 129.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 124.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 115.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 110.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 107.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 98.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 92.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 91.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 89.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 85.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 83.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 63.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 283.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 283.6
FF:10158-103A5 76 years, female 283.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 305.8
Pig sample Sample description nTPM
Midbrain
nTPM: 305.8
Samples: 4

Max nTPM: 630.4
Min nTPM: 127.6
Sample A Female 630.4
Sample B Female 309.3
Sample C Male 127.6
Sample D Male 155.7
Periaqueductal gray
nTPM: 213.1
Samples: 3

Max nTPM: 254.2
Min nTPM: 171.2
Sample B Female 254.2
Sample C Male 171.2
Sample D Male 214.0
Substantia nigra
nTPM: 277.4
Samples: 4

Max nTPM: 420.4
Min nTPM: 157.3
Sample A Female 327.8
Sample B Female 204.1
Sample C Male 157.3
Sample D Male 420.4
Superior colliculi
nTPM: 220.9
Samples: 4

Max nTPM: 298.5
Min nTPM: 126.7
Sample A Female 298.5
Sample B Female 126.7
Sample C Male 192.5
Sample D Male 265.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 23.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 23.7
Samples: 4

Max nTPM: 29.7
Min nTPM: 18.4
Sample A Male 29.7
Sample B Male 18.4
Sample C Female 22.8
Sample D Female 23.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.6
70546384 Antisense, RP_050623_04_C01, Mouse strain C57BL/6J (56 days, male) 0.6

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