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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:214.5 nTPM
HPA:214.5 nTPM
GTEx:112.7 nTPM
FANTOM5:405.7 Scaled Tags Per Million
Pig:162.4 nTPM
Mouse:28.1 nTPM
Allen mouse:5.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 214.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 153.2
1830 Male, age 51, unknown 229.3
1833 Male, age 53, unknown 192.7
2586 Male, age 75, left hemisphere 165.7
2411 Female, age 72, unknown 161.0
2019 Male, age 18, unknown 160.6
1870 Female, age 42, unknown 158.3
2666 Male, age 74, left hemisphere 144.6
2828 Female, age 72, unknown 128.4
1827 Male, age 72, unknown 96.7
2219 Male, age 76, both hemispheres 95.1
Dorsal raphe nucleus
nTPM: 102.2
2750 Male, age 76, both hemispheres 208.2
2016 Female, age 72, unknown 121.1
1828 Male, age 53, unknown 93.5
2047 Male, age 72, unknown 55.3
2298 Female, age 72, unknown 32.9
Inferior colliculus
nTPM: 91.9
2849 Male, age 72, unknown 121.7
1848 Female, age 42, unknown 102.0
1890 Male, age 53, unknown 94.7
2097 Female, age 72, unknown 49.3
Median raphe nucleus
nTPM: 78.9
2220 Male, age 76, midline 78.9
Pedunculopontine tegmental nucleus
nTPM: 140.6
2338 Male, age 61, both hemispheres 168.5
2334 Male, age 80, both hemispheres 151.0
1921 Female, age 85, both hemispheres 102.2
Periaquaductal grey, anterior
nTPM: 88.0
2502 Female, age 75, unknown 103.6
1947 Male, age 18, unknown 92.7
1795 Male, age 51, unknown 67.6
Periaquaductal grey, dorsal
nTPM: 66.0
2464 Female, age 72, unknown 112.2
1831 Male, age 72, unknown 69.7
1840 Male, age 53, unknown 47.1
2850 Male, age 76, both hemispheres 34.9
Periaquaductal grey, lateral
nTPM: 64.1
2272 Male, age 74, both hemispheres 83.3
2053 Male, age 18, unknown 76.1
2140 Male, age 76, both hemispheres 32.8
Pretectal area
nTPM: 88.3
2316 Male, age 76, right hemisphere 149.1
2407 Male, age 75, both hemispheres 146.4
1815 Male, age 53, unknown 135.3
2825 Male, age 18, unknown 105.2
1817 Female, age 42, unknown 92.5
2007 Male, age 72, unknown 78.7
2273 Male, age 74, both hemispheres 68.8
2224 Female, age 72, unknown 62.1
2667 Female, age 75, unknown 45.6
1816 Male, age 51, unknown 44.7
1944 Female, age 72, unknown 42.9
Red nucleus
nTPM: 214.5
1865 Male, age 51, unknown 246.3
2503 Female, age 72, unknown 244.0
1904 Male, age 53, unknown 243.0
2227 Male, age 72, unknown 239.5
2823 Male, age 76, right hemisphere 239.5
2769 Male, age 72, unknown 213.6
2588 Male, age 74, left hemisphere 211.7
1821 Female, age 72, unknown 204.8
1954 Female, age 42, unknown 201.3
2785 Male, age 18, unknown 186.1
2725 Female, age 75, unknown 175.4
2584 Male, age 75, left hemisphere 169.2
Substantia nigra
nTPM: 113.5
2590 Female, age 75, unknown 160.6
2583 Male, age 75, right hemisphere 152.8
2699 Male, age 18, unknown 131.7
2665 Male, age 74, both hemispheres 124.4
1851 Male, age 51, unknown 122.2
1889 Female, age 72, unknown 103.4
2241 Male, age 72, unknown 99.6
2409 Female, age 72, unknown 97.1
1941 Male, age 53, unknown 80.6
1916 Female, age 42, unknown 62.4
Superior colliculus
nTPM: 131.0
1913 Female, age 42, unknown 193.3
1995 Male, age 72, unknown 191.7
1895 Male, age 76, right hemisphere 151.8
2587 Male, age 74, left hemisphere 145.5
2668 Female, age 75, unknown 144.9
1839 Male, age 51, unknown 140.8
2664 Male, age 75, both hemispheres 120.4
1796 Male, age 53, unknown 87.5
2087 Female, age 72, unknown 67.0
2261 Male, age 18, unknown 67.0
Ventral tegmental area
nTPM: 127.7
2223 Female, age 72, unknown 193.2
2410 Female, age 72, unknown 148.9
1942 Male, age 51, unknown 109.9
2021 Male, age 53, unknown 107.4
2218 Male, age 76, both hemispheres 107.0
1915 Female, age 42, unknown 99.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 112.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 112.7
Samples: 139

Max nTPM: 340.8
Min nTPM: 27.0
Std nTPM: 59.0
Median nTPM: 99.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 340.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 305.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 282.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 276.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 275.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 255.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 228.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 227.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 227.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 219.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 203.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 203.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 195.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 194.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 179.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 179.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 178.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 177.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 173.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 170.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 169.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 166.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 164.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 161.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 156.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 155.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 153.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 151.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 150.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 150.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 145.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 143.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 143.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 141.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 140.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 138.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 134.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 134.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 133.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 132.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 132.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 129.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 127.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 126.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 126.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 125.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 125.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 125.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 120.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 120.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 120.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 119.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 119.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 119.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 117.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 116.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 113.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 113.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 113.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 110.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 110.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 108.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 108.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 107.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 105.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 103.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 102.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 102.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 101.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 99.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 98.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 97.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 97.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 97.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 95.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 94.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 93.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 93.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 91.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 91.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 90.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 90.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 88.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 88.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 87.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 84.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 84.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 83.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 82.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 80.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 80.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 78.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 77.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 76.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 76.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 74.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 74.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 73.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 73.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 72.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 72.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 71.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 70.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 68.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 68.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 68.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 67.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 66.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 63.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 63.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 62.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 62.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 61.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 61.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 59.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 59.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 58.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 57.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 57.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 56.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 56.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 56.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 56.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 52.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 51.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 51.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 50.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 50.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 49.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 49.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 47.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 47.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 45.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 44.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 42.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 39.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 36.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 32.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 27.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 405.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 405.7
FF:10158-103A5 76 years, female 405.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 162.4
Pig sample Sample description nTPM
Midbrain
nTPM: 155.2
Samples: 4

Max nTPM: 268.0
Min nTPM: 89.7
Sample A Female 268.0
Sample B Female 171.3
Sample C Male 89.7
Sample D Male 91.8
Periaqueductal gray
nTPM: 120.6
Samples: 3

Max nTPM: 144.8
Min nTPM: 94.0
Sample B Female 144.8
Sample C Male 94.0
Sample D Male 123.1
Substantia nigra
nTPM: 162.4
Samples: 4

Max nTPM: 252.2
Min nTPM: 125.8
Sample A Female 142.1
Sample B Female 125.8
Sample C Male 129.5
Sample D Male 252.2
Superior colliculi
nTPM: 119.5
Samples: 4

Max nTPM: 157.3
Min nTPM: 68.0
Sample A Female 123.7
Sample B Female 68.0
Sample C Male 129.1
Sample D Male 157.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 28.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 28.1
Samples: 4

Max nTPM: 30.6
Min nTPM: 26.2
Sample A Male 26.4
Sample B Male 26.2
Sample C Female 29.1
Sample D Female 30.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 5.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 5.0
68844468 Antisense, RP_050222_01_F10, Mouse strain C57BL/6J (56 days, male) 5.9
71924066 Antisense, RP_051017_02_H07, Mouse strain C57BL/6J (56 days, male) 4.2

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