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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:237.2 nTPM
HPA:237.2 nTPM
GTEx:184.6 nTPM
FANTOM5:173.4 Scaled Tags Per Million
Pig:68.8 nTPM
Mouse:385.4 nTPM
Allen mouse:8.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 237.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 228.3
2019 Male, age 18, unknown 238.9
1827 Male, age 72, unknown 235.3
1870 Female, age 42, unknown 231.9
2411 Female, age 72, unknown 231.9
2666 Male, age 74, left hemisphere 226.3
2586 Male, age 75, left hemisphere 225.4
2828 Female, age 72, unknown 224.6
2219 Male, age 76, both hemispheres 223.8
1833 Male, age 53, unknown 223.0
1830 Male, age 51, unknown 221.8
Dorsal raphe nucleus
nTPM: 232.2
2298 Female, age 72, unknown 247.9
1828 Male, age 53, unknown 232.1
2047 Male, age 72, unknown 230.7
2750 Male, age 76, both hemispheres 229.1
2016 Female, age 72, unknown 221.2
Inferior colliculus
nTPM: 229.3
2097 Female, age 72, unknown 243.7
1890 Male, age 53, unknown 230.1
1848 Female, age 42, unknown 225.5
2849 Male, age 72, unknown 217.9
Median raphe nucleus
nTPM: 225.0
2220 Male, age 76, midline 225.0
Pedunculopontine tegmental nucleus
nTPM: 232.1
2334 Male, age 80, both hemispheres 233.5
1921 Female, age 85, both hemispheres 232.4
2338 Male, age 61, both hemispheres 230.4
Periaquaductal grey, anterior
nTPM: 228.6
1795 Male, age 51, unknown 228.9
1947 Male, age 18, unknown 228.5
2502 Female, age 75, unknown 228.4
Periaquaductal grey, dorsal
nTPM: 222.9
1840 Male, age 53, unknown 226.0
1831 Male, age 72, unknown 224.6
2464 Female, age 72, unknown 223.3
2850 Male, age 76, both hemispheres 217.9
Periaquaductal grey, lateral
nTPM: 222.1
2053 Male, age 18, unknown 224.9
2272 Male, age 74, both hemispheres 222.7
2140 Male, age 76, both hemispheres 218.6
Pretectal area
nTPM: 233.9
2007 Male, age 72, unknown 247.8
1816 Male, age 51, unknown 246.8
1944 Female, age 72, unknown 240.3
1817 Female, age 42, unknown 239.7
1815 Male, age 53, unknown 234.2
2224 Female, age 72, unknown 232.3
2667 Female, age 75, unknown 231.5
2273 Male, age 74, both hemispheres 228.8
2316 Male, age 76, right hemisphere 226.7
2825 Male, age 18, unknown 223.7
2407 Male, age 75, both hemispheres 221.4
Red nucleus
nTPM: 226.4
1821 Female, age 72, unknown 240.3
2785 Male, age 18, unknown 231.1
2725 Female, age 75, unknown 229.0
2503 Female, age 72, unknown 226.9
2823 Male, age 76, right hemisphere 225.8
2769 Male, age 72, unknown 225.1
1954 Female, age 42, unknown 225.0
1904 Male, age 53, unknown 223.9
1865 Male, age 51, unknown 223.8
2227 Male, age 72, unknown 223.3
2584 Male, age 75, left hemisphere 223.3
2588 Male, age 74, left hemisphere 218.8
Substantia nigra
nTPM: 237.2
1851 Male, age 51, unknown 248.4
1916 Female, age 42, unknown 246.7
1889 Female, age 72, unknown 242.7
2241 Male, age 72, unknown 242.1
1941 Male, age 53, unknown 242.0
2409 Female, age 72, unknown 238.9
2665 Male, age 74, both hemispheres 231.1
2590 Female, age 75, unknown 229.5
2583 Male, age 75, right hemisphere 226.5
2699 Male, age 18, unknown 224.1
Superior colliculus
nTPM: 228.6
2087 Female, age 72, unknown 238.0
2668 Female, age 75, unknown 233.3
2261 Male, age 18, unknown 231.5
1796 Male, age 53, unknown 230.7
2587 Male, age 74, left hemisphere 230.7
1895 Male, age 76, right hemisphere 228.9
1913 Female, age 42, unknown 225.5
2664 Male, age 75, both hemispheres 223.1
1839 Male, age 51, unknown 222.8
1995 Male, age 72, unknown 221.3
Ventral tegmental area
nTPM: 231.1
1915 Female, age 42, unknown 241.8
2410 Female, age 72, unknown 240.2
2218 Male, age 76, both hemispheres 227.2
2223 Female, age 72, unknown 226.8
1942 Male, age 51, unknown 226.2
2021 Male, age 53, unknown 224.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 184.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 184.6
Samples: 139

Max nTPM: 386.1
Min nTPM: 96.7
Std nTPM: 51.8
Median nTPM: 169.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 386.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 345.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 325.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 308.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 303.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 299.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 297.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 293.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 276.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 276.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 274.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 274.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 270.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 263.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 255.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 251.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 251.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 248.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 242.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 237.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 234.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 233.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 228.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 226.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 225.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 223.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 223.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 221.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 220.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 219.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 218.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 217.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 214.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 213.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 208.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 208.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 208.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 206.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 205.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 204.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 203.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 201.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 201.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 198.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 196.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 195.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 194.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 193.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 192.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 191.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 191.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 190.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 190.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 189.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 186.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 186.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 186.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 185.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 184.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 183.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 179.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 179.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 179.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 176.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 176.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 175.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 175.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 173.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 171.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 169.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 167.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 167.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 167.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 167.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 164.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 163.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 162.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 162.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 161.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 161.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 159.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 158.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 158.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 158.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 157.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 156.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 156.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 156.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 155.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 155.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 154.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 154.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 154.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 153.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 153.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 152.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 152.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 152.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 152.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 151.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 151.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 150.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 150.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 149.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 149.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 148.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 148.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 148.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 147.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 145.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 145.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 145.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 144.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 143.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 142.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 140.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 140.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 140.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 138.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 134.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 134.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 132.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 131.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 131.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 131.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 130.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 129.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 129.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 129.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 128.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 127.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 123.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 122.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 122.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 122.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 115.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 112.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 111.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 96.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 173.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 173.4
FF:10158-103A5 76 years, female 173.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 68.8
Pig sample Sample description nTPM
Midbrain
nTPM: 60.9
Samples: 4

Max nTPM: 77.4
Min nTPM: 48.1
Sample A Female 48.1
Sample B Female 52.1
Sample C Male 77.4
Sample D Male 65.9
Periaqueductal gray
nTPM: 42.3
Samples: 3

Max nTPM: 51.2
Min nTPM: 36.3
Sample B Female 39.3
Sample C Male 51.2
Sample D Male 36.3
Substantia nigra
nTPM: 50.9
Samples: 4

Max nTPM: 79.9
Min nTPM: 30.0
Sample A Female 79.9
Sample B Female 38.9
Sample C Male 54.9
Sample D Male 30.0
Superior colliculi
nTPM: 68.8
Samples: 4

Max nTPM: 84.9
Min nTPM: 48.3
Sample A Female 83.9
Sample B Female 48.3
Sample C Male 84.9
Sample D Male 58.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 385.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 385.4
Samples: 4

Max nTPM: 425.2
Min nTPM: 338.8
Sample A Male 425.2
Sample B Male 387.1
Sample C Female 338.8
Sample D Female 390.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 8.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 8.3
69735001 Antisense, RP_050503_01_H04, Mouse strain C57BL/6J (56 days, male) 9.4
73520984 Antisense, RP_051101_02_G03, Mouse strain C57BL/6J (56 days, male) 7.2

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