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TISSUE MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM ENDOMETRIUM
EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MEDULLA OBLONGATA MIDBRAIN OVARY
PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PONS PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE SMOOTH MUSCLE
SPINAL CORD SPLEEN STOMACH TESTIS THALAMUS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA WHITE MATTER
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:59.2 nTPM
HPA:59.2 nTPM
GTEx:77.0 nTPM
FANTOM5:45.9 Scaled Tags Per Million
Pig:50.9 nTPM
Mouse:125.6 nTPM
Allen mouse:3.6 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 59.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 54.6
2586 Male, age 75, left hemisphere 59.4
2219 Male, age 76, both hemispheres 56.4
2411 Female, age 72, unknown 56.4
1827 Male, age 72, unknown 56.2
2828 Female, age 72, unknown 56.1
2019 Male, age 18, unknown 54.0
1870 Female, age 42, unknown 53.6
1833 Male, age 53, unknown 53.1
1830 Male, age 51, unknown 52.4
2666 Male, age 74, left hemisphere 48.7
Dorsal raphe nucleus
nTPM: 56.9
2298 Female, age 72, unknown 63.5
2047 Male, age 72, unknown 57.7
2750 Male, age 76, both hemispheres 57.1
1828 Male, age 53, unknown 55.5
2016 Female, age 72, unknown 50.8
Inferior colliculus
nTPM: 51.4
2097 Female, age 72, unknown 52.7
1848 Female, age 42, unknown 51.4
1890 Male, age 53, unknown 50.8
2849 Male, age 72, unknown 50.5
Median raphe nucleus
nTPM: 57.7
2220 Male, age 76, midline 57.7
Pedunculopontine tegmental nucleus
nTPM: 54.3
2334 Male, age 80, both hemispheres 57.8
1921 Female, age 85, both hemispheres 54.3
2338 Male, age 61, both hemispheres 50.8
Periaquaductal grey, anterior
nTPM: 56.1
1947 Male, age 18, unknown 57.0
1795 Male, age 51, unknown 55.9
2502 Female, age 75, unknown 55.5
Periaquaductal grey, dorsal
nTPM: 51.8
1840 Male, age 53, unknown 53.6
2850 Male, age 76, both hemispheres 52.4
1831 Male, age 72, unknown 51.6
2464 Female, age 72, unknown 49.5
Periaquaductal grey, lateral
nTPM: 53.1
2272 Male, age 74, both hemispheres 58.2
2053 Male, age 18, unknown 50.7
2140 Male, age 76, both hemispheres 50.6
Pretectal area
nTPM: 55.4
2667 Female, age 75, unknown 59.5
1944 Female, age 72, unknown 58.5
2007 Male, age 72, unknown 58.3
1816 Male, age 51, unknown 57.7
2273 Male, age 74, both hemispheres 56.9
1817 Female, age 42, unknown 56.4
2224 Female, age 72, unknown 56.0
1815 Male, age 53, unknown 55.2
2407 Male, age 75, both hemispheres 51.1
2825 Male, age 18, unknown 51.1
2316 Male, age 76, right hemisphere 49.2
Red nucleus
nTPM: 54.0
1821 Female, age 72, unknown 56.0
1904 Male, age 53, unknown 56.0
2588 Male, age 74, left hemisphere 55.9
2785 Male, age 18, unknown 55.9
1865 Male, age 51, unknown 54.7
2227 Male, age 72, unknown 54.4
2769 Male, age 72, unknown 54.2
2725 Female, age 75, unknown 53.9
2503 Female, age 72, unknown 53.5
1954 Female, age 42, unknown 52.5
2584 Male, age 75, left hemisphere 51.1
2823 Male, age 76, right hemisphere 50.2
Substantia nigra
nTPM: 59.2
1916 Female, age 42, unknown 72.2
1851 Male, age 51, unknown 66.2
2699 Male, age 18, unknown 61.8
1941 Male, age 53, unknown 57.5
1889 Female, age 72, unknown 57.1
2409 Female, age 72, unknown 56.0
2241 Male, age 72, unknown 55.7
2583 Male, age 75, right hemisphere 55.5
2590 Female, age 75, unknown 55.3
2665 Male, age 74, both hemispheres 54.8
Superior colliculus
nTPM: 54.3
1796 Male, age 53, unknown 58.7
2261 Male, age 18, unknown 56.4
2087 Female, age 72, unknown 56.1
2668 Female, age 75, unknown 54.3
1913 Female, age 42, unknown 54.0
2587 Male, age 74, left hemisphere 54.0
2664 Male, age 75, both hemispheres 53.8
1995 Male, age 72, unknown 52.4
1895 Male, age 76, right hemisphere 51.9
1839 Male, age 51, unknown 51.6
Ventral tegmental area
nTPM: 59.0
2410 Female, age 72, unknown 65.4
1915 Female, age 42, unknown 62.3
2218 Male, age 76, both hemispheres 61.8
2223 Female, age 72, unknown 55.0
1942 Male, age 51, unknown 54.8
2021 Male, age 53, unknown 54.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 77.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 77.0
Samples: 139

Max nTPM: 158.3
Min nTPM: 39.5
Std nTPM: 19.3
Median nTPM: 73.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 158.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 149.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 127.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 125.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 116.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 114.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 109.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 107.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 105.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 105.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 105.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 101.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 101.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 100.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 99.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 98.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 98.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 96.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 96.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 95.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 94.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 94.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 93.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 93.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 92.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 92.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 91.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 90.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 90.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 89.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 89.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 89.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 88.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 87.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 87.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 86.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 86.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 85.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 85.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 84.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 84.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 84.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 84.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 83.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 83.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 83.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 83.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 83.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 82.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 82.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 82.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 82.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 81.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 81.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 80.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 80.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 79.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 78.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 78.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 77.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 77.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 77.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 76.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 76.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 76.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 76.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 76.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 75.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 75.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 73.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 73.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 73.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 73.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 73.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 73.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 72.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 71.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 71.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 71.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 71.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 71.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 71.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 70.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 69.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 69.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 69.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 68.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 68.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 68.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 68.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 68.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 67.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 67.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 67.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 67.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 66.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 66.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 66.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 66.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 65.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 65.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 65.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 65.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 65.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 64.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 64.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 64.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 63.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 63.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 62.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 61.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 61.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 61.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 60.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 60.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 59.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 58.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 58.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 57.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 57.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 56.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 55.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 55.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 54.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 54.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 54.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 53.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 53.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 51.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 51.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 51.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 50.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 49.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 49.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 46.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 46.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 46.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 44.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 39.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 45.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 45.9
FF:10158-103A5 76 years, female 45.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 50.9
Pig sample Sample description nTPM
Midbrain
nTPM: 50.6
Samples: 4

Max nTPM: 58.5
Min nTPM: 43.9
Sample A Female 58.5
Sample B Female 44.4
Sample C Male 55.4
Sample D Male 43.9
Periaqueductal gray
nTPM: 39.8
Samples: 3

Max nTPM: 45.1
Min nTPM: 34.3
Sample B Female 40.0
Sample C Male 45.1
Sample D Male 34.3
Substantia nigra
nTPM: 50.9
Samples: 4

Max nTPM: 59.2
Min nTPM: 41.6
Sample A Female 59.0
Sample B Female 41.6
Sample C Male 59.2
Sample D Male 43.7
Superior colliculi
nTPM: 50.8
Samples: 4

Max nTPM: 57.3
Min nTPM: 43.0
Sample A Female 53.7
Sample B Female 43.0
Sample C Male 57.3
Sample D Male 49.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 125.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 125.6
Samples: 4

Max nTPM: 129.9
Min nTPM: 122.1
Sample A Male 127.6
Sample B Male 122.1
Sample C Female 122.8
Sample D Female 129.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 3.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.6
67978711 Antisense, RP_040923_01_F07, Mouse strain C57BL/6J (56 days, male) 3.6

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