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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 138.5
Min nTPM: 48.9
Std nTPM: 16.4
Median nTPM:
413_1
59 years, female
138.5
491_1
89 years, female
130.1
501_1
88 years, male
128.9
139_1
64 years, female
116.6
43_1
64 years, female
116.4
81_1
67 years, male
112.9
142_1
61 years, female
112.5
120_1
70 years, female
112.0
17_1
71 years, male
111.7
149_1
88 years, male
110.0
490_1
67 years, female
108.9
288_1
66 years, female
108.4
506_1
65 years, male
107.7
89_1
63 years, male
105.5
2_1
77 years, female
104.5
324_1
76 years, male
104.0
119_1
70 years, female
103.9
145_1
84 years, male
103.7
109_1
81 years, female
103.6
316_1
62 years, male
102.5
322_1
76 years, male
101.5
315_1
62 years, female
101.2
6_1
73 years, female
101.1
18_1
88 years, male
100.8
99_1
64 years, male
100.5
42_1
85 years, male
100.2
162_1
79 years, female
99.8
518_1
75 years, female
97.8
4_1
88 years, female
96.9
415_1
77 years, female
96.9
466_1
57 years, female
96.6
32_1
67 years, male
96.2
115_1
83 years, male
95.7
117_1
61 years, male
94.9
314_1
67 years, male
94.0
35_1
74 years, female
93.6
348_1
84 years, male
92.6
313_1
79 years, female
92.1
126_1
63 years, male
91.7
353_1
82 years, female
90.6
452_1
88 years, female
90.5
377_1
82 years, female
89.6
173_1
67 years, male
88.6
254_1
77 years, female
88.6
386_1
76 years, male
88.0
396_1
62 years, male
87.9
335_1
73 years, female
86.2
311_1
78 years, male
86.1
495_1
57 years, female
85.7
243_1
75 years, male
85.6
41_1
94 years, female
85.2
266_1
85 years, male
84.4
9_1
66 years, female
83.9
447_1
81 years, male
83.9
291_1
76 years, male
83.6
379_1
60 years, male
82.5
320_1
89 years, female
81.4
307_1
66 years, female
81.2
217_1
76 years, male
80.8
317_1
60 years, male
80.6
153_1
70 years, female
80.5
292_1
71 years, male
80.3
468_1
89 years, male
80.1
347_1
72 years, male
80.0
499_1
55 years, female
80.0
137_1
83 years, male
79.8
425_1
59 years, female
79.1
295_1
61 years, female
78.9
265_1
87 years, male
78.8
404_1
82 years, female
78.7
526_1
61 years, male
78.7
293_1
68 years, female
78.4
286_1
68 years, female
78.2
351_1
91 years, male
78.1
229_1
69 years, female
78.0
264_1
73 years, female
78.0
321_1
62 years, female
77.9
517_1
88 years, male
77.6
352_1
62 years, male
77.4
375_1
74 years, female
75.3
251_1
78 years, male
74.9
350_1
84 years, female
74.8
405_1
91 years, male
74.4
414_1
84 years, female
74.3
480_1
63 years, male
74.3
177_1
74 years, male
73.7
172_1
72 years, female
73.1
318_1
68 years, male
72.9
406_1
79 years, male
72.8
355_1
70 years, female
72.6
356_1
87 years, female
72.0
237_1
82 years, male
71.6
319_1
81 years, male
71.4
376_1
75 years, female
71.3
308_1
70 years, female
71.2
503_1
68 years, male
67.5
349_1
83 years, male
67.3
354_1
81 years, female
66.8
246_1
77 years, male
65.8
189_1
76 years, male
64.2
384_1
83 years, male
62.7
163_1
78 years, male
60.7
218_1
71 years, female
53.9
389_1
86 years, female
49.9
394_1
75 years, female
48.9
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
