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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:82.1 nTPM
HPA:82.1 nTPM
GTEx:108.5 nTPM
FANTOM5:24.3 Scaled Tags Per Million
Pig:127.4 nTPM
Mouse:390.2 nTPM
Allen mouse:29.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 82.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 40.1
2219 Male, age 76, both hemispheres 57.9
1827 Male, age 72, unknown 54.0
2411 Female, age 72, unknown 48.0
1870 Female, age 42, unknown 47.0
1833 Male, age 53, unknown 46.1
2666 Male, age 74, left hemisphere 39.8
1830 Male, age 51, unknown 33.4
2828 Female, age 72, unknown 30.2
2586 Male, age 75, left hemisphere 26.4
2019 Male, age 18, unknown 18.7
Dorsal raphe nucleus
nTPM: 50.5
2298 Female, age 72, unknown 80.1
2750 Male, age 76, both hemispheres 58.3
2047 Male, age 72, unknown 53.9
2016 Female, age 72, unknown 30.8
1828 Male, age 53, unknown 29.2
Inferior colliculus
nTPM: 56.6
2097 Female, age 72, unknown 71.3
2849 Male, age 72, unknown 56.1
1848 Female, age 42, unknown 51.4
1890 Male, age 53, unknown 47.5
Median raphe nucleus
nTPM: 82.1
2220 Male, age 76, midline 82.1
Pedunculopontine tegmental nucleus
nTPM: 52.1
1921 Female, age 85, both hemispheres 77.5
2334 Male, age 80, both hemispheres 54.4
2338 Male, age 61, both hemispheres 24.3
Periaquaductal grey, anterior
nTPM: 75.4
2502 Female, age 75, unknown 104.9
1795 Male, age 51, unknown 63.0
1947 Male, age 18, unknown 58.4
Periaquaductal grey, dorsal
nTPM: 63.1
1840 Male, age 53, unknown 84.0
1831 Male, age 72, unknown 68.9
2850 Male, age 76, both hemispheres 54.4
2464 Female, age 72, unknown 45.1
Periaquaductal grey, lateral
nTPM: 49.0
2053 Male, age 18, unknown 68.5
2140 Male, age 76, both hemispheres 51.6
2272 Male, age 74, both hemispheres 27.0
Pretectal area
nTPM: 64.9
2667 Female, age 75, unknown 126.8
1944 Female, age 72, unknown 100.9
1816 Male, age 51, unknown 93.8
2224 Female, age 72, unknown 82.0
2825 Male, age 18, unknown 71.6
1817 Female, age 42, unknown 52.6
1815 Male, age 53, unknown 51.8
2316 Male, age 76, right hemisphere 46.3
2407 Male, age 75, both hemispheres 38.6
2007 Male, age 72, unknown 30.6
2273 Male, age 74, both hemispheres 18.6
Red nucleus
nTPM: 25.2
2584 Male, age 75, left hemisphere 36.3
1821 Female, age 72, unknown 32.2
1954 Female, age 42, unknown 31.1
2503 Female, age 72, unknown 28.0
2769 Male, age 72, unknown 27.7
2227 Male, age 72, unknown 25.9
1904 Male, age 53, unknown 25.1
2588 Male, age 74, left hemisphere 24.5
2823 Male, age 76, right hemisphere 20.7
2725 Female, age 75, unknown 17.8
1865 Male, age 51, unknown 16.6
2785 Male, age 18, unknown 16.0
Substantia nigra
nTPM: 52.5
1916 Female, age 42, unknown 81.1
2665 Male, age 74, both hemispheres 70.2
2241 Male, age 72, unknown 61.8
1851 Male, age 51, unknown 59.1
1889 Female, age 72, unknown 56.0
2699 Male, age 18, unknown 52.3
1941 Male, age 53, unknown 50.5
2409 Female, age 72, unknown 49.6
2583 Male, age 75, right hemisphere 23.7
2590 Female, age 75, unknown 20.2
Superior colliculus
nTPM: 50.8
2087 Female, age 72, unknown 83.1
2261 Male, age 18, unknown 80.3
1796 Male, age 53, unknown 57.9
1895 Male, age 76, right hemisphere 57.6
1839 Male, age 51, unknown 49.7
2668 Female, age 75, unknown 40.6
1913 Female, age 42, unknown 37.0
1995 Male, age 72, unknown 34.9
2664 Male, age 75, both hemispheres 34.9
2587 Male, age 74, left hemisphere 32.4
Ventral tegmental area
nTPM: 59.9
2218 Male, age 76, both hemispheres 78.6
2410 Female, age 72, unknown 68.6
1915 Female, age 42, unknown 64.6
2021 Male, age 53, unknown 60.3
1942 Male, age 51, unknown 52.5
2223 Female, age 72, unknown 35.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 108.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 108.5
Samples: 139

Max nTPM: 302.7
Min nTPM: 7.5
Std nTPM: 68.2
Median nTPM: 98.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 302.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 300.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 291.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 260.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 245.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 241.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 233.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 231.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 231.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 223.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 222.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 215.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 211.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 209.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 206.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 204.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 201.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 197.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 196.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 189.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 185.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 182.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 181.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 180.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 175.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 170.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 168.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 162.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 160.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 160.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 158.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 157.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 148.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 147.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 146.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 143.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 142.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 141.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 139.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 139.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 138.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 138.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 136.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 136.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 135.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 135.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 134.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 134.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 133.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 129.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 129.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 128.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 127.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 126.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 125.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 124.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 124.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 123.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 122.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 121.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 118.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 116.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 115.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 110.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 107.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 107.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 102.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 100.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 100.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 98.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 98.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 96.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 94.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 91.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 91.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 87.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 86.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 86.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 85.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 83.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 82.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 80.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 79.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 77.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 77.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 75.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 75.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 73.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 72.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 72.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 65.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 62.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 62.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 60.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 59.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 59.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 59.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 57.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 55.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 55.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 53.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 52.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 52.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 51.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 47.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 47.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 46.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 42.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 42.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 41.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 41.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 41.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 41.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 41.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 40.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 40.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 39.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 39.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 39.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 36.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 35.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 34.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 32.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 32.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 31.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 27.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 27.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 26.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 26.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 26.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 25.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 23.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 21.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 19.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 17.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 14.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 14.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 11.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 7.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 24.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 24.3
FF:10158-103A5 76 years, female 24.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 127.4
Pig sample Sample description nTPM
Midbrain
nTPM: 127.4
Samples: 4

Max nTPM: 225.7
Min nTPM: 30.3
Sample A Female 30.3
Sample B Female 88.2
Sample C Male 165.4
Sample D Male 225.7
Periaqueductal gray
nTPM: 97.9
Samples: 3

Max nTPM: 127.9
Min nTPM: 74.5
Sample B Female 91.3
Sample C Male 127.9
Sample D Male 74.5
Substantia nigra
nTPM: 99.8
Samples: 4

Max nTPM: 153.3
Min nTPM: 32.8
Sample A Female 143.1
Sample B Female 69.9
Sample C Male 153.3
Sample D Male 32.8
Superior colliculi
nTPM: 100.2
Samples: 4

Max nTPM: 188.7
Min nTPM: 25.2
Sample A Female 188.7
Sample B Female 25.2
Sample C Male 62.3
Sample D Male 124.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 390.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 390.3
Samples: 4

Max nTPM: 398.7
Min nTPM: 383.1
Sample A Male 398.7
Sample B Male 391.5
Sample C Female 383.1
Sample D Female 387.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 29.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 29.9
67767440 Antisense, RP_040916_01_G10, Mouse strain C57BL/6J (56 days, male) 29.9

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