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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:68.8 nTPM
HPA:68.8 nTPM
GTEx:105.3 nTPM
FANTOM5:219.8 Scaled Tags Per Million
Pig:50.7 nTPM
Mouse:72.0 nTPM
Allen mouse:1.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 68.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 65.9
1870 Female, age 42, unknown 68.8
2019 Male, age 18, unknown 68.6
2411 Female, age 72, unknown 66.2
2586 Male, age 75, left hemisphere 65.8
1833 Male, age 53, unknown 65.7
2828 Female, age 72, unknown 65.4
1827 Male, age 72, unknown 65.3
1830 Male, age 51, unknown 65.3
2666 Male, age 74, left hemisphere 64.1
2219 Male, age 76, both hemispheres 63.6
Dorsal raphe nucleus
nTPM: 67.8
2298 Female, age 72, unknown 68.8
2750 Male, age 76, both hemispheres 68.5
1828 Male, age 53, unknown 67.7
2047 Male, age 72, unknown 67.3
2016 Female, age 72, unknown 66.5
Inferior colliculus
nTPM: 66.2
1890 Male, age 53, unknown 69.9
2097 Female, age 72, unknown 67.8
1848 Female, age 42, unknown 65.1
2849 Male, age 72, unknown 61.8
Median raphe nucleus
nTPM: 65.4
2220 Male, age 76, midline 65.4
Pedunculopontine tegmental nucleus
nTPM: 65.5
2334 Male, age 80, both hemispheres 68.2
1921 Female, age 85, both hemispheres 66.4
2338 Male, age 61, both hemispheres 61.7
Periaquaductal grey, anterior
nTPM: 64.7
1947 Male, age 18, unknown 68.3
2502 Female, age 75, unknown 63.2
1795 Male, age 51, unknown 62.5
Periaquaductal grey, dorsal
nTPM: 62.5
2464 Female, age 72, unknown 64.1
1831 Male, age 72, unknown 62.9
2850 Male, age 76, both hemispheres 62.4
1840 Male, age 53, unknown 60.7
Periaquaductal grey, lateral
nTPM: 62.4
2272 Male, age 74, both hemispheres 65.0
2053 Male, age 18, unknown 63.4
2140 Male, age 76, both hemispheres 58.9
Pretectal area
nTPM: 65.9
2007 Male, age 72, unknown 69.1
2667 Female, age 75, unknown 68.2
1944 Female, age 72, unknown 67.6
1817 Female, age 42, unknown 66.5
2407 Male, age 75, both hemispheres 66.1
1815 Male, age 53, unknown 65.8
1816 Male, age 51, unknown 65.8
2273 Male, age 74, both hemispheres 65.7
2224 Female, age 72, unknown 64.9
2825 Male, age 18, unknown 63.3
2316 Male, age 76, right hemisphere 61.7
Red nucleus
nTPM: 68.8
1821 Female, age 72, unknown 73.7
1904 Male, age 53, unknown 71.0
1954 Female, age 42, unknown 70.9
1865 Male, age 51, unknown 70.0
2823 Male, age 76, right hemisphere 69.8
2227 Male, age 72, unknown 69.4
2503 Female, age 72, unknown 69.1
2769 Male, age 72, unknown 68.9
2785 Male, age 18, unknown 67.7
2725 Female, age 75, unknown 66.7
2588 Male, age 74, left hemisphere 64.5
2584 Male, age 75, left hemisphere 64.4
Substantia nigra
nTPM: 67.7
1851 Male, age 51, unknown 70.8
2241 Male, age 72, unknown 69.5
1889 Female, age 72, unknown 69.1
1941 Male, age 53, unknown 68.5
2409 Female, age 72, unknown 68.2
1916 Female, age 42, unknown 68.0
2583 Male, age 75, right hemisphere 67.5
2590 Female, age 75, unknown 66.5
2699 Male, age 18, unknown 65.5
2665 Male, age 74, both hemispheres 63.3
Superior colliculus
nTPM: 65.8
2668 Female, age 75, unknown 67.9
1895 Male, age 76, right hemisphere 67.6
1913 Female, age 42, unknown 67.3
2587 Male, age 74, left hemisphere 67.1
2087 Female, age 72, unknown 65.9
2664 Male, age 75, both hemispheres 65.7
1995 Male, age 72, unknown 65.2
1839 Male, age 51, unknown 64.3
2261 Male, age 18, unknown 63.9
1796 Male, age 53, unknown 62.9
Ventral tegmental area
nTPM: 66.0
1915 Female, age 42, unknown 66.9
2223 Female, age 72, unknown 66.4
1942 Male, age 51, unknown 66.3
2410 Female, age 72, unknown 66.0
2218 Male, age 76, both hemispheres 65.8
2021 Male, age 53, unknown 64.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 105.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 105.3
Samples: 139

Max nTPM: 189.1
Min nTPM: 46.8
Std nTPM: 21.8
Median nTPM: 102.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 189.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 168.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 159.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 157.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 153.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 147.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 143.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 141.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 140.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 139.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 135.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 133.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 133.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 132.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 131.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 131.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 129.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 129.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 129.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 128.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 127.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 127.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 126.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 125.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 122.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 122.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 122.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 122.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 121.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 119.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 119.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 118.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 118.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 118.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 117.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 116.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 116.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 115.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 115.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 115.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 114.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 114.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 114.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 114.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 113.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 113.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 113.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 112.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 112.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 111.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 111.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 111.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 110.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 110.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 109.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 108.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 108.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 107.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 107.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 106.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 106.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 106.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 105.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 105.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 105.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 105.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 105.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 104.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 102.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 102.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 101.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 101.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 101.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 101.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 100.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 100.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 99.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 99.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 97.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 97.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 97.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 97.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 97.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 96.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 96.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 96.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 96.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 96.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 96.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 95.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 95.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 94.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 94.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 94.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 94.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 94.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 94.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 93.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 93.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 92.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 92.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 92.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 91.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 91.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 91.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 91.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 90.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 89.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 89.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 88.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 87.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 87.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 87.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 86.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 86.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 86.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 86.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 85.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 85.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 84.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 83.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 83.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 82.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 82.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 82.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 82.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 80.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 79.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 79.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 78.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 78.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 77.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 73.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 72.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 70.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 69.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 60.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 54.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 46.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 219.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 219.8
FF:10158-103A5 76 years, female 219.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 50.7
Pig sample Sample description nTPM
Midbrain
nTPM: 46.0
Samples: 4

Max nTPM: 57.7
Min nTPM: 40.0
Sample A Female 57.7
Sample B Female 42.7
Sample C Male 40.0
Sample D Male 43.4
Periaqueductal gray
nTPM: 37.5
Samples: 3

Max nTPM: 40.3
Min nTPM: 36.0
Sample B Female 40.3
Sample C Male 36.0
Sample D Male 36.3
Substantia nigra
nTPM: 39.5
Samples: 4

Max nTPM: 51.9
Min nTPM: 29.8
Sample A Female 51.9
Sample B Female 29.8
Sample C Male 33.3
Sample D Male 42.8
Superior colliculi
nTPM: 50.7
Samples: 4

Max nTPM: 64.7
Min nTPM: 30.3
Sample A Female 60.4
Sample B Female 30.3
Sample C Male 64.7
Sample D Male 47.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 72.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 72.0
Samples: 4

Max nTPM: 75.6
Min nTPM: 68.9
Sample A Male 75.6
Sample B Male 71.2
Sample C Female 68.9
Sample D Female 72.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 1.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.0
70303534 Antisense, RP_050609_01_F12, Mouse strain C57BL/6J (56 days, male) 1.3
73930820 Antisense, RP_051214_04_C04, Mouse strain C57BL/6J (56 days, male) 0.6

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