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BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:280.9 nTPM
HPA:280.9 nTPM
FANTOM5:118.9 Scaled Tags Per Million
Pig:314.0 nTPM
Allen mouse:18.8 Expression energy

PONS - HPA Brain RNA-seq
Max nTPM 280.9
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 196.6
1984 Male, age 76, both hemispheres 206.7
2090 Male, age 80, both hemispheres 196.2
2188 Female, age 91, both hemispheres 192.8
2301 Female, age 85, both hemispheres 190.9
Dorsal cochlear nucleus
nTPM: 212.1
2802 Male, age 74, right hemisphere 227.1
2058 Male, age 76, both hemispheres 221.4
2187 Female, age 91, both hemispheres 216.1
2370 Male, age 61, both hemispheres 206.6
2378 Male, age 80, both hemispheres 189.5
Dorsal tegmental nucleus
nTPM: 218.3
2083 Male, age 80, both hemispheres 235.9
2326 Male, age 74, both hemispheres 220.5
1936 Male, age 76, left hemisphere 210.2
2358 Male, age 61, both hemispheres 206.6
Dorsolateral tegmental area
nTPM: 221.5
2751 Female, age 85, both hemispheres 242.1
2654 Male, age 80, both hemispheres 236.2
2141 Male, age 76, both hemispheres 226.5
2360 Male, age 74, both hemispheres 216.1
2337 Male, age 61, both hemispheres 186.6
Kolliker-Fuse nucleus
nTPM: 216.2
2163 Male, age 80, both hemispheres 248.9
2315 Male, age 76, right hemisphere 217.0
2793 Female, age 91, left hemisphere 182.7
Lateral lemniscal nuclei
nTPM: 212.6
2169 Male, age 76, both hemispheres 231.1
2036 Male, age 80, both hemispheres 220.4
2453 Male, age 74, right hemisphere 216.6
2746 Female, age 85, left hemisphere 216.1
2320 Female, age 91, left hemisphere 178.6
Lateral parabrachial nucleus
nTPM: 209.8
2139 Female, age 85, right hemisphere 232.2
2790 Male, age 61, both hemispheres 212.4
2013 Male, age 80, both hemispheres 207.8
2792 Male, age 76, both hemispheres 186.7
Lateral vestibular nucleus
nTPM: 221.6
2184 Male, age 76, both hemispheres 238.1
2311 Male, age 80, both hemispheres 205.2
Locus coeruleus
nTPM: 280.9
2123 Female, age 91, both hemispheres 331.1
2014 Male, age 55, unknown 305.3
1980 Male, age 76, both hemispheres 276.6
2317 Female, age 72, unknown 275.9
2720 Male, age 74, both hemispheres 270.4
2788 Male, age 74, unknown 255.6
2162 Male, age 80, both hemispheres 251.2
Medial olivary nucleus
nTPM: 194.2
2138 Female, age 91, both hemispheres 223.7
1962 Male, age 76, both hemispheres 193.3
2851 Male, age 80, both hemispheres 180.8
1943 Male, age 61, both hemispheres 178.8
Medial parabrachial nucleus
nTPM: 224.0
2170 Female, age 91, both hemispheres 240.2
2463 Female, age 85, right hemisphere 230.6
2156 Male, age 61, both hemispheres 221.8
2786 Male, age 76, both hemispheres 216.3
2854 Male, age 80, both hemispheres 211.3
Medial periolivary nuclei
nTPM: 216.3
2063 Male, age 76, both hemispheres 249.4
2171 Female, age 85, both hemispheres 248.9
2791 Male, age 74, right hemisphere 220.7
2081 Male, age 80, both hemispheres 184.9
2458 Female, age 91, both hemispheres 177.5
Motor facial nucleus
nTPM: 212.4
2062 Male, age 76, both hemispheres 259.4
2365 Male, age 74, right hemisphere 221.7
2126 Male, age 61, both hemispheres 213.7
2795 Female, age 91, both hemispheres 205.5
2697 Female, age 85, both hemispheres 189.6
2327 Male, age 80, both hemispheres 184.4
Motor trigeminal nucleus
nTPM: 204.6
2309 Male, age 76, both hemispheres 219.2
2335 Male, age 61, both hemispheres 215.9
2079 Male, age 80, both hemispheres 208.5
2560 Male, age 74, both hemispheres 200.3
2321 Female, age 91, both hemispheres 179.3
Nuclei of the trapezoid body
nTPM: 230.9
2159 Male, age 61, both hemispheres 274.2
2735 Female, age 85, both hemispheres 247.8
1983 Male, age 76, both hemispheres 245.3
2166 Male, age 80, both hemispheres 197.9
2368 Female, age 91, both hemispheres 189.5
Paramedian reticular nucleus
nTPM: 242.1
2057 Male, age 80, both hemispheres 263.3
2050 Female, age 85, both hemispheres 255.6
2313 Male, age 61, both hemispheres 252.7
2052 Male, age 76, both hemispheres 196.8
Pontine nuclei
nTPM: 234.9
2727 Male, age 61, right hemisphere 300.2
1863 Male, age 55, unknown 270.7
2787 Female, age 85, both hemispheres 256.0
2109 Female, age 72, unknown 242.4
1968 Male, age 76, left hemisphere 230.2
2454 Male, age 74, left hemisphere 205.4
2115 Male, age 80, left hemisphere 188.3
2319 Female, age 91, both hemispheres 185.8
Pontine raphe nucleus
nTPM: 243.9
2122 Female, age 85, midline 247.0
2853 Male, age 76, midline 240.8
Posteroventral cochlear nucleus
nTPM: 211.5
2752 Female, age 85, both hemispheres 254.9
2070 Male, age 76, both hemispheres 219.2
2371 Male, age 61, both hemispheres 203.4
2341 Male, age 80, both hemispheres 190.5
2135 Female, age 91, both hemispheres 189.7
Principal sensory trigeminal nucleus
nTPM: 221.2
2158 Male, age 61, both hemispheres 266.4
2324 Male, age 76, both hemispheres 222.2
2008 Male, age 80, left hemisphere 218.3
2367 Female, age 91, left hemisphere 178.0
Reticular pontine nucleus, caudal
nTPM: 203.6
2092 Male, age 76, both hemispheres 221.5
2559 Male, age 74, both hemispheres 208.1
2332 Male, age 80, right hemisphere 201.8
2457 Female, age 91, both hemispheres 183.1
Reticular pontine nucleus, oral
nTPM: 222.3
1939 Male, age 80, both hemispheres 248.8
2012 Female, age 85, both hemispheres 237.8
2167 Male, age 76, both hemispheres 231.0
2361 Male, age 74, both hemispheres 208.6
2366 Female, age 91, both hemispheres 185.1
Reticulotegmental nucleus
nTPM: 222.2
2325 Male, age 76, both hemispheres 239.5
2452 Male, age 74, both hemispheres 222.9
2333 Male, age 80, both hemispheres 214.9
2322 Female, age 91, both hemispheres 211.4
Spinal trigeminal nucleus, oral
nTPM: 222.7
2737 Female, age 85, both hemispheres 239.9
2164 Male, age 80, both hemispheres 220.0
1978 Male, age 76, both hemispheres 208.3
Subcoeruleus area
nTPM: 229.2
2323 Female, age 91, left hemisphere 248.3
2451 Male, age 74, both hemispheres 232.6
1958 Male, age 80, both hemispheres 230.8
2369 Female, age 85, left hemisphere 228.8
2089 Male, age 76, left hemisphere 205.4
Superior olive
nTPM: 207.8
1875 Female, age 85, both hemispheres 236.7
2364 Male, age 74, right hemisphere 224.5
2020 Male, age 76, both hemispheres 210.0
2329 Male, age 80, right hemisphere 187.6
2561 Female, age 91, both hemispheres 180.4
Superior vestibular nucleus
nTPM: 227.8
2383 Male, age 74, both hemispheres 231.7
2061 Male, age 76, both hemispheres 225.8
2015 Male, age 80, both hemispheres 225.7
Ventral periolivary nuclei
nTPM: 213.0
2165 Male, age 80, both hemispheres 231.1
2130 Female, age 85, both hemispheres 230.1
2023 Male, age 76, both hemispheres 207.5
2794 Female, age 91, left hemisphere 183.2
Ventrolateral tegmental area, A5 NE cell group
nTPM: 209.2
2359 Male, age 61, both hemispheres 226.1
2449 Male, age 74, both hemispheres 221.1
2840 Female, age 85, both hemispheres 214.0
1959 Male, age 76, both hemispheres 212.2
2161 Male, age 80, both hemispheres 197.5
2456 Female, age 91, both hemispheres 184.1

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 118.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 76.0
FF:10182-103D2 60 years, female 77.1
FF:10165-103B3 76 years, female 75.0
Pons
Scaled Tags Per Million: 118.9
FF:10033-101E6 18-54 years, mixed 118.9

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
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Average nTPM 314.0
Pig sample Sample description nTPM
Pons
nTPM: 314.1
Samples: 4

Max nTPM: 378.7
Min nTPM: 225.9
Sample A Female 378.7
Sample B Female 225.9
Sample C Male 291.1
Sample D Male 360.5

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 18.8
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 18.8
513469 Antisense, RP_040810_01_F11, Mouse strain C57BL/6J (56 days, male) 18.8

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.