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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:242.7 nTPM
HPA:242.7 nTPM
GTEx:287.2 nTPM
FANTOM5:33.4 Scaled Tags Per Million
Pig:301.0 nTPM
Mouse:588.4 nTPM
Allen mouse:22.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 242.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 222.6
2411 Female, age 72, unknown 245.2
1827 Male, age 72, unknown 240.6
2586 Male, age 75, left hemisphere 237.5
2019 Male, age 18, unknown 229.9
2828 Female, age 72, unknown 222.6
1870 Female, age 42, unknown 217.8
2219 Male, age 76, both hemispheres 213.2
2666 Male, age 74, left hemisphere 210.5
1833 Male, age 53, unknown 208.6
1830 Male, age 51, unknown 199.6
Dorsal raphe nucleus
nTPM: 235.4
2298 Female, age 72, unknown 274.5
2047 Male, age 72, unknown 241.1
1828 Male, age 53, unknown 231.2
2750 Male, age 76, both hemispheres 225.0
2016 Female, age 72, unknown 204.8
Inferior colliculus
nTPM: 233.5
2097 Female, age 72, unknown 271.9
1890 Male, age 53, unknown 233.8
1848 Female, age 42, unknown 226.5
2849 Male, age 72, unknown 201.9
Median raphe nucleus
nTPM: 236.9
2220 Male, age 76, midline 236.9
Pedunculopontine tegmental nucleus
nTPM: 232.6
1921 Female, age 85, both hemispheres 248.8
2334 Male, age 80, both hemispheres 242.0
2338 Male, age 61, both hemispheres 207.0
Periaquaductal grey, anterior
nTPM: 237.6
1947 Male, age 18, unknown 244.5
1795 Male, age 51, unknown 234.1
2502 Female, age 75, unknown 234.1
Periaquaductal grey, dorsal
nTPM: 210.2
1840 Male, age 53, unknown 224.4
2464 Female, age 72, unknown 210.5
1831 Male, age 72, unknown 210.4
2850 Male, age 76, both hemispheres 195.7
Periaquaductal grey, lateral
nTPM: 201.5
2272 Male, age 74, both hemispheres 207.2
2053 Male, age 18, unknown 202.5
2140 Male, age 76, both hemispheres 194.7
Pretectal area
nTPM: 235.3
1816 Male, age 51, unknown 272.6
2007 Male, age 72, unknown 266.5
1817 Female, age 42, unknown 263.5
1944 Female, age 72, unknown 260.1
2667 Female, age 75, unknown 251.5
1815 Male, age 53, unknown 234.1
2224 Female, age 72, unknown 222.1
2273 Male, age 74, both hemispheres 213.9
2825 Male, age 18, unknown 209.1
2316 Male, age 76, right hemisphere 202.2
2407 Male, age 75, both hemispheres 193.2
Red nucleus
nTPM: 217.9
1821 Female, age 72, unknown 248.8
2725 Female, age 75, unknown 227.6
1954 Female, age 42, unknown 227.5
2785 Male, age 18, unknown 223.4
2588 Male, age 74, left hemisphere 218.5
2503 Female, age 72, unknown 217.8
2769 Male, age 72, unknown 215.0
2227 Male, age 72, unknown 214.9
1904 Male, age 53, unknown 210.9
2823 Male, age 76, right hemisphere 208.3
1865 Male, age 51, unknown 205.7
2584 Male, age 75, left hemisphere 196.3
Substantia nigra
nTPM: 242.7
1916 Female, age 42, unknown 301.0
1851 Male, age 51, unknown 262.1
1889 Female, age 72, unknown 260.4
2241 Male, age 72, unknown 254.0
1941 Male, age 53, unknown 251.8
2665 Male, age 74, both hemispheres 231.5
2409 Female, age 72, unknown 221.9
2699 Male, age 18, unknown 218.9
2590 Female, age 75, unknown 214.0
2583 Male, age 75, right hemisphere 211.0
Superior colliculus
nTPM: 218.2
2087 Female, age 72, unknown 256.1
2261 Male, age 18, unknown 239.3
1796 Male, age 53, unknown 236.5
2668 Female, age 75, unknown 217.8
1895 Male, age 76, right hemisphere 214.9
1839 Male, age 51, unknown 209.9
2587 Male, age 74, left hemisphere 209.8
2664 Male, age 75, both hemispheres 207.4
1913 Female, age 42, unknown 197.8
1995 Male, age 72, unknown 192.6
Ventral tegmental area
nTPM: 238.5
1915 Female, age 42, unknown 264.7
2410 Female, age 72, unknown 257.2
2218 Male, age 76, both hemispheres 247.7
1942 Male, age 51, unknown 235.0
2223 Female, age 72, unknown 215.7
2021 Male, age 53, unknown 210.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 287.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 287.2
Samples: 139

Max nTPM: 536.8
Min nTPM: 120.5
Std nTPM: 89.9
Median nTPM: 272.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 536.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 521.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 520.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 506.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 499.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 489.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 468.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 458.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 442.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 440.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 437.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 428.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 420.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 416.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 413.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 411.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 405.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 390.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 385.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 384.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 383.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 376.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 372.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 372.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 371.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 371.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 368.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 364.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 356.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 350.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 345.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 345.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 343.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 340.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 339.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 338.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 336.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 335.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 329.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 325.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 323.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 317.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 317.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 316.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 315.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 314.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 311.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 310.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 306.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 303.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 303.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 302.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 301.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 301.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 297.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 294.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 292.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 291.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 289.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 288.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 288.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 288.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 285.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 284.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 281.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 281.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 280.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 279.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 275.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 272.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 272.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 271.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 269.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 269.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 269.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 266.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 263.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 263.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 262.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 259.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 258.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 257.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 256.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 254.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 250.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 249.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 249.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 249.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 248.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 248.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 248.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 245.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 244.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 242.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 242.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 242.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 241.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 239.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 237.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 230.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 230.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 229.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 229.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 228.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 223.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 222.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 218.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 215.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 211.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 211.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 210.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 209.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 209.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 209.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 206.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 204.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 202.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 201.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 198.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 196.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 195.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 195.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 191.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 190.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 184.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 178.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 176.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 174.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 172.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 163.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 160.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 153.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 149.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 144.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 139.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 137.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 137.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 124.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 120.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 33.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 33.4
FF:10158-103A5 76 years, female 33.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 301.0
Pig sample Sample description nTPM
Midbrain
nTPM: 257.0
Samples: 4

Max nTPM: 334.4
Min nTPM: 201.3
Sample A Female 204.8
Sample B Female 201.3
Sample C Male 334.4
Sample D Male 287.6
Periaqueductal gray
nTPM: 198.8
Samples: 3

Max nTPM: 239.0
Min nTPM: 169.5
Sample B Female 188.0
Sample C Male 239.0
Sample D Male 169.5
Substantia nigra
nTPM: 225.9
Samples: 4

Max nTPM: 304.1
Min nTPM: 153.5
Sample A Female 304.1
Sample B Female 164.0
Sample C Male 282.0
Sample D Male 153.5
Superior colliculi
nTPM: 301.0
Samples: 4

Max nTPM: 358.3
Min nTPM: 204.9
Sample A Female 349.3
Sample B Female 204.9
Sample C Male 358.3
Sample D Male 291.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 588.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 588.4
Samples: 4

Max nTPM: 594.4
Min nTPM: 573.4
Sample A Male 594.0
Sample B Male 591.9
Sample C Female 573.4
Sample D Female 594.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 22.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 22.0
513469 Antisense, RP_040810_01_F11, Mouse strain C57BL/6J (56 days, male) 22.0

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