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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:211.6 nTPM
HPA:211.6 nTPM
GTEx:120.9 nTPM
FANTOM5:14.6 Scaled Tags Per Million
Pig:56.1 nTPM
Mouse:20.4 nTPM
Allen mouse:0.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 211.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 201.5
2586 Male, age 75, left hemisphere 210.3
2019 Male, age 18, unknown 202.9
2828 Female, age 72, unknown 201.5
2411 Female, age 72, unknown 201.4
1827 Male, age 72, unknown 200.9
1830 Male, age 51, unknown 200.7
1833 Male, age 53, unknown 200.4
2666 Male, age 74, left hemisphere 199.4
2219 Male, age 76, both hemispheres 198.8
1870 Female, age 42, unknown 198.7
Dorsal raphe nucleus
nTPM: 202.8
2047 Male, age 72, unknown 205.1
2298 Female, age 72, unknown 205.0
1828 Male, age 53, unknown 202.3
2750 Male, age 76, both hemispheres 201.3
2016 Female, age 72, unknown 200.4
Inferior colliculus
nTPM: 206.0
1848 Female, age 42, unknown 215.0
1890 Male, age 53, unknown 204.0
2097 Female, age 72, unknown 202.7
2849 Male, age 72, unknown 202.2
Median raphe nucleus
nTPM: 201.4
2220 Male, age 76, midline 201.4
Pedunculopontine tegmental nucleus
nTPM: 211.6
2334 Male, age 80, both hemispheres 216.7
2338 Male, age 61, both hemispheres 212.9
1921 Female, age 85, both hemispheres 205.1
Periaquaductal grey, anterior
nTPM: 199.9
2502 Female, age 75, unknown 202.3
1947 Male, age 18, unknown 199.4
1795 Male, age 51, unknown 198.1
Periaquaductal grey, dorsal
nTPM: 200.6
1840 Male, age 53, unknown 202.9
2464 Female, age 72, unknown 202.0
1831 Male, age 72, unknown 199.8
2850 Male, age 76, both hemispheres 197.8
Periaquaductal grey, lateral
nTPM: 198.7
2053 Male, age 18, unknown 202.9
2272 Male, age 74, both hemispheres 197.3
2140 Male, age 76, both hemispheres 195.9
Pretectal area
nTPM: 202.4
1817 Female, age 42, unknown 208.3
1816 Male, age 51, unknown 205.5
2273 Male, age 74, both hemispheres 205.5
2407 Male, age 75, both hemispheres 204.0
2667 Female, age 75, unknown 203.6
1944 Female, age 72, unknown 201.6
2007 Male, age 72, unknown 200.5
2316 Male, age 76, right hemisphere 200.4
2825 Male, age 18, unknown 200.1
1815 Male, age 53, unknown 198.8
2224 Female, age 72, unknown 198.4
Red nucleus
nTPM: 204.7
1821 Female, age 72, unknown 211.9
1954 Female, age 42, unknown 210.5
2227 Male, age 72, unknown 206.7
2769 Male, age 72, unknown 206.5
2503 Female, age 72, unknown 205.2
2588 Male, age 74, left hemisphere 205.2
1865 Male, age 51, unknown 204.3
1904 Male, age 53, unknown 203.4
2823 Male, age 76, right hemisphere 201.2
2785 Male, age 18, unknown 200.9
2725 Female, age 75, unknown 200.7
2584 Male, age 75, left hemisphere 199.5
Substantia nigra
nTPM: 209.6
1941 Male, age 53, unknown 220.9
2665 Male, age 74, both hemispheres 213.4
1916 Female, age 42, unknown 211.1
2241 Male, age 72, unknown 211.0
2699 Male, age 18, unknown 211.0
1889 Female, age 72, unknown 206.9
1851 Male, age 51, unknown 206.3
2583 Male, age 75, right hemisphere 206.0
2409 Female, age 72, unknown 205.1
2590 Female, age 75, unknown 204.0
Superior colliculus
nTPM: 204.1
2668 Female, age 75, unknown 208.2
2664 Male, age 75, both hemispheres 206.6
1839 Male, age 51, unknown 206.0
1796 Male, age 53, unknown 205.4
2587 Male, age 74, left hemisphere 204.9
2087 Female, age 72, unknown 203.9
1995 Male, age 72, unknown 202.1
2261 Male, age 18, unknown 201.6
1895 Male, age 76, right hemisphere 201.5
1913 Female, age 42, unknown 200.5
Ventral tegmental area
nTPM: 210.8
2223 Female, age 72, unknown 241.0
1942 Male, age 51, unknown 208.1
1915 Female, age 42, unknown 205.5
2410 Female, age 72, unknown 205.5
2021 Male, age 53, unknown 204.2
2218 Male, age 76, both hemispheres 200.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 120.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 120.9
Samples: 139

Max nTPM: 583.3
Min nTPM: 18.8
Std nTPM: 78.5
Median nTPM: 103.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 583.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 477.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 377.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 347.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 230.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 221.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 213.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 211.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 211.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 209.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 205.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 204.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 203.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 203.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 202.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 200.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 199.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 197.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 196.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 193.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 188.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 187.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 185.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 183.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 180.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 179.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 178.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 173.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 168.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 168.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 164.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 161.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 160.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 159.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 159.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 156.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 153.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 152.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 150.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 148.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 144.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 143.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 140.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 140.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 138.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 138.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 137.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 132.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 132.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 131.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 131.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 130.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 126.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 125.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 124.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 122.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 121.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 120.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 119.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 117.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 115.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 114.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 114.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 113.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 113.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 110.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 108.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 107.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 103.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 103.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 101.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 101.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 100.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 98.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 97.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 94.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 94.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 92.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 92.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 91.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 90.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 90.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 90.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 89.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 87.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 84.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 83.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 82.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 82.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 82.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 81.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 81.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 80.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 80.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 77.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 76.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 76.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 73.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 70.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 68.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 68.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 68.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 68.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 67.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 67.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 66.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 63.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 63.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 63.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 62.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 61.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 60.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 60.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 59.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 58.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 56.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 55.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 54.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 52.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 51.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 51.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 50.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 48.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 48.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 48.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 47.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 45.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 44.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 44.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 44.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 43.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 43.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 41.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 41.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 37.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 37.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 33.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 29.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 18.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 14.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 14.6
FF:10158-103A5 76 years, female 14.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 56.1
Pig sample Sample description nTPM
Midbrain
nTPM: 56.1
Samples: 4

Max nTPM: 76.5
Min nTPM: 32.0
Sample A Female 76.5
Sample B Female 75.3
Sample C Male 32.0
Sample D Male 40.7
Periaqueductal gray
nTPM: 45.0
Samples: 3

Max nTPM: 54.9
Min nTPM: 37.2
Sample B Female 54.9
Sample C Male 37.2
Sample D Male 42.8
Substantia nigra
nTPM: 53.2
Samples: 4

Max nTPM: 70.1
Min nTPM: 39.4
Sample A Female 70.1
Sample B Female 57.2
Sample C Male 39.4
Sample D Male 45.9
Superior colliculi
nTPM: 52.4
Samples: 4

Max nTPM: 65.6
Min nTPM: 39.7
Sample A Female 52.9
Sample B Female 65.6
Sample C Male 39.7
Sample D Male 51.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 20.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 20.5
Samples: 4

Max nTPM: 26.3
Min nTPM: 16.0
Sample A Male 26.3
Sample B Male 20.2
Sample C Female 16.0
Sample D Female 19.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.2
79670592 Antisense, RP_071204_01_E01, Mouse strain C57BL/6J (56 days, male) 0.2
79556716 Antisense, RP_071204_01_E01, Mouse strain C57BL/6J (56 days, male) 0.2
2298 Antisense, RP_040604_01_D02, Mouse strain C57BL/6J (56 days, male) 0.1

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