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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:151.8 nTPM
HPA:151.8 nTPM
GTEx:192.8 nTPM
FANTOM5:144.4 Scaled Tags Per Million
Pig:29.1 nTPM
Mouse:231.2 nTPM
Allen mouse:2.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 151.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 131.4
2219 Male, age 76, both hemispheres 135.2
2411 Female, age 72, unknown 135.2
1870 Female, age 42, unknown 135.0
1833 Male, age 53, unknown 134.8
1827 Male, age 72, unknown 134.4
1830 Male, age 51, unknown 134.3
2019 Male, age 18, unknown 131.8
2828 Female, age 72, unknown 128.0
2666 Male, age 74, left hemisphere 125.5
2586 Male, age 75, left hemisphere 119.4
Dorsal raphe nucleus
nTPM: 136.6
2750 Male, age 76, both hemispheres 140.3
1828 Male, age 53, unknown 137.1
2298 Female, age 72, unknown 136.9
2047 Male, age 72, unknown 134.9
2016 Female, age 72, unknown 133.6
Inferior colliculus
nTPM: 130.8
2849 Male, age 72, unknown 135.6
2097 Female, age 72, unknown 130.9
1848 Female, age 42, unknown 129.1
1890 Male, age 53, unknown 127.6
Median raphe nucleus
nTPM: 151.8
2220 Male, age 76, midline 151.8
Pedunculopontine tegmental nucleus
nTPM: 146.8
2334 Male, age 80, both hemispheres 152.1
2338 Male, age 61, both hemispheres 149.6
1921 Female, age 85, both hemispheres 138.8
Periaquaductal grey, anterior
nTPM: 129.8
1947 Male, age 18, unknown 131.8
1795 Male, age 51, unknown 129.7
2502 Female, age 75, unknown 127.7
Periaquaductal grey, dorsal
nTPM: 132.5
2850 Male, age 76, both hemispheres 147.3
1840 Male, age 53, unknown 129.9
2464 Female, age 72, unknown 126.7
1831 Male, age 72, unknown 126.0
Periaquaductal grey, lateral
nTPM: 133.5
2140 Male, age 76, both hemispheres 135.8
2053 Male, age 18, unknown 132.5
2272 Male, age 74, both hemispheres 132.3
Pretectal area
nTPM: 134.8
2667 Female, age 75, unknown 141.9
2224 Female, age 72, unknown 139.7
1817 Female, age 42, unknown 138.8
2825 Male, age 18, unknown 136.2
1816 Male, age 51, unknown 135.7
1815 Male, age 53, unknown 134.8
1944 Female, age 72, unknown 134.8
2007 Male, age 72, unknown 134.0
2273 Male, age 74, both hemispheres 131.4
2316 Male, age 76, right hemisphere 128.4
2407 Male, age 75, both hemispheres 127.2
Red nucleus
nTPM: 134.1
1821 Female, age 72, unknown 143.7
2725 Female, age 75, unknown 140.5
2823 Male, age 76, right hemisphere 139.3
2503 Female, age 72, unknown 137.9
1954 Female, age 42, unknown 137.5
1904 Male, age 53, unknown 134.0
2227 Male, age 72, unknown 133.6
1865 Male, age 51, unknown 132.9
2769 Male, age 72, unknown 128.9
2588 Male, age 74, left hemisphere 128.1
2785 Male, age 18, unknown 128.0
2584 Male, age 75, left hemisphere 125.4
Substantia nigra
nTPM: 138.9
1916 Female, age 42, unknown 147.1
2409 Female, age 72, unknown 147.0
2241 Male, age 72, unknown 146.8
2699 Male, age 18, unknown 141.1
1941 Male, age 53, unknown 139.8
2665 Male, age 74, both hemispheres 138.2
1851 Male, age 51, unknown 137.3
1889 Female, age 72, unknown 137.1
2590 Female, age 75, unknown 131.1
2583 Male, age 75, right hemisphere 123.8
Superior colliculus
nTPM: 129.6
1895 Male, age 76, right hemisphere 133.8
2587 Male, age 74, left hemisphere 133.4
1913 Female, age 42, unknown 132.7
2087 Female, age 72, unknown 131.5
1839 Male, age 51, unknown 131.1
1796 Male, age 53, unknown 129.6
2261 Male, age 18, unknown 129.4
1995 Male, age 72, unknown 127.8
2668 Female, age 75, unknown 126.4
2664 Male, age 75, both hemispheres 120.0
Ventral tegmental area
nTPM: 137.3
2218 Male, age 76, both hemispheres 144.5
1915 Female, age 42, unknown 139.0
2223 Female, age 72, unknown 138.6
2021 Male, age 53, unknown 135.5
2410 Female, age 72, unknown 134.0
1942 Male, age 51, unknown 132.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 192.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 192.8
Samples: 139

Max nTPM: 323.1
Min nTPM: 105.5
Std nTPM: 38.8
Median nTPM: 192.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 323.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 290.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 285.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 284.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 277.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 267.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 264.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 262.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 257.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 256.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 253.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 248.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 248.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 244.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 242.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 240.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 240.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 237.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 237.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 233.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 233.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 233.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 232.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 231.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 220.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 219.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 219.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 218.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 217.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 217.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 216.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 216.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 216.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 215.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 214.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 214.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 212.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 212.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 211.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 210.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 210.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 209.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 209.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 207.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 206.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 206.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 206.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 205.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 205.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 205.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 205.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 205.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 204.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 204.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 203.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 203.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 202.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 202.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 200.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 200.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 198.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 198.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 196.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 196.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 195.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 194.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 194.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 194.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 192.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 192.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 191.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 190.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 189.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 187.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 186.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 186.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 186.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 184.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 182.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 182.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 182.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 181.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 181.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 180.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 179.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 179.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 178.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 176.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 176.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 176.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 175.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 174.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 173.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 171.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 170.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 170.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 170.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 169.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 169.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 168.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 168.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 167.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 166.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 163.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 163.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 161.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 160.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 160.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 159.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 158.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 157.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 156.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 154.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 154.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 153.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 153.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 153.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 151.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 151.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 151.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 150.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 149.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 148.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 147.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 147.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 147.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 146.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 145.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 144.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 141.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 140.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 137.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 134.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 131.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 130.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 129.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 127.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 116.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 105.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 144.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 144.4
FF:10158-103A5 76 years, female 144.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 29.1
Pig sample Sample description nTPM
Midbrain
nTPM: 25.9
Samples: 4

Max nTPM: 28.4
Min nTPM: 22.5
Sample A Female 28.4
Sample B Female 26.3
Sample C Male 26.3
Sample D Male 22.5
Periaqueductal gray
nTPM: 25.5
Samples: 3

Max nTPM: 32.5
Min nTPM: 21.7
Sample B Female 22.4
Sample C Male 32.5
Sample D Male 21.7
Substantia nigra
nTPM: 26.6
Samples: 4

Max nTPM: 37.8
Min nTPM: 19.4
Sample A Female 37.8
Sample B Female 21.8
Sample C Male 27.3
Sample D Male 19.4
Superior colliculi
nTPM: 29.2
Samples: 4

Max nTPM: 41.9
Min nTPM: 20.7
Sample A Female 29.4
Sample B Female 24.6
Sample C Male 41.9
Sample D Male 20.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 231.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 231.2
Samples: 4

Max nTPM: 244.2
Min nTPM: 224.2
Sample A Male 229.6
Sample B Male 244.2
Sample C Female 226.9
Sample D Female 224.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 2.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.3
68861975 Antisense, RP_050301_01_C05, Mouse strain C57BL/6J (56 days, male) 2.3

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