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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 155.6
Min nTPM: 41.0
Std nTPM: 18.0
Median nTPM:
375_1
74 years, female
155.6
177_1
74 years, male
138.2
350_1
84 years, female
129.3
173_1
67 years, male
127.7
396_1
62 years, male
127.7
347_1
72 years, male
124.9
384_1
83 years, male
124.2
386_1
76 years, male
122.3
379_1
60 years, male
121.7
4_1
88 years, female
120.7
292_1
71 years, male
117.6
377_1
82 years, female
116.7
237_1
82 years, male
116.4
318_1
68 years, male
115.7
319_1
81 years, male
115.6
406_1
79 years, male
115.3
414_1
84 years, female
114.1
316_1
62 years, male
113.0
163_1
78 years, male
111.1
351_1
91 years, male
110.3
425_1
59 years, female
110.1
189_1
76 years, male
109.3
109_1
81 years, female
106.2
313_1
79 years, female
106.1
264_1
73 years, female
105.8
286_1
68 years, female
105.8
349_1
83 years, male
105.2
120_1
70 years, female
105.0
295_1
61 years, female
105.0
405_1
91 years, male
104.9
506_1
65 years, male
104.7
266_1
85 years, male
104.6
404_1
82 years, female
104.3
99_1
64 years, male
103.0
265_1
87 years, male
102.7
501_1
88 years, male
102.6
335_1
73 years, female
102.5
413_1
59 years, female
102.1
243_1
75 years, male
101.6
324_1
76 years, male
101.6
229_1
69 years, female
100.7
447_1
81 years, male
100.5
452_1
88 years, female
100.0
320_1
89 years, female
99.7
356_1
87 years, female
99.6
480_1
63 years, male
99.4
317_1
60 years, male
98.4
315_1
62 years, female
98.1
139_1
64 years, female
97.8
348_1
84 years, male
97.4
394_1
75 years, female
96.5
352_1
62 years, male
95.9
376_1
75 years, female
95.5
468_1
89 years, male
95.0
35_1
74 years, female
94.5
353_1
82 years, female
94.1
526_1
61 years, male
94.0
251_1
78 years, male
93.8
517_1
88 years, male
93.6
42_1
85 years, male
93.1
503_1
68 years, male
93.1
2_1
77 years, female
92.3
145_1
84 years, male
92.2
6_1
73 years, female
92.1
153_1
70 years, female
90.7
172_1
72 years, female
90.5
254_1
77 years, female
90.5
314_1
67 years, male
90.0
218_1
71 years, female
89.3
518_1
75 years, female
89.3
17_1
71 years, male
88.8
389_1
86 years, female
88.7
354_1
81 years, female
88.4
322_1
76 years, male
88.2
246_1
77 years, male
87.6
18_1
88 years, male
86.7
41_1
94 years, female
86.6
115_1
83 years, male
86.3
321_1
62 years, female
86.3
355_1
70 years, female
85.0
119_1
70 years, female
84.7
291_1
76 years, male
84.3
137_1
83 years, male
83.4
9_1
66 years, female
83.0
415_1
77 years, female
82.2
117_1
61 years, male
82.1
293_1
68 years, female
81.5
162_1
79 years, female
81.3
311_1
78 years, male
80.1
142_1
61 years, female
79.9
466_1
57 years, female
79.6
43_1
64 years, female
77.6
217_1
76 years, male
77.3
499_1
55 years, female
77.1
126_1
63 years, male
76.9
288_1
66 years, female
72.9
32_1
67 years, male
72.6
89_1
63 years, male
72.1
81_1
67 years, male
71.9
490_1
67 years, female
67.5
307_1
66 years, female
64.4
149_1
88 years, male
61.5
308_1
70 years, female
54.3
491_1
89 years, female
46.7
495_1
57 years, female
41.0
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
