MOUSE BRAIN TISSUE
Gene description Secretogranin II
Mouse gene ENSMUSG00000050711 (version 10)
Annotation summary Similar staining to SCG2 but somehow more restricted in terms of anatomical distribution. Moderate-strong diffuse-synaptic immunoreactivity is noticed in some distinct brain areas: Strong diffuse-synaptic immunostaining is noticed in the lateral septum, ventral pallidum, shall of the nucleus accumbens, the preoptic area, some nuclei of BNST, some nuclei of the tuberal hypothalamus (paraventricular-, dorsomedial-, periventricular and arcuate nuclei), thalamic paraventricular nucleus, hippocampus mossy fibers, central amygdala, periaqueductal gray matter, some nuclei of the medulla, like parabrachial nucleus, dorsal raphe, locus coeruleus. Moderate-weak synaptic immunoreactivity is noticed in all layers of the olfactory bulb, in midline thalamic nuclei, substantia nigra, and some medullar nuclei. The median eminence and area postrema exhibits strong immunoreactivity.
Positive cells and structuresi Synapse in neurons.
Circumventricular organs of ependymal cells.
FRONT BACK
Olfactory bulb
Hypothalamus
Midbrain
Medulla
Hippocampus
Protein
Relative fluorescence intensityi
Mouse brain region
255
0
Cerebral cortex
Frontal association cortex (fra) N/A
Motor cortex (m)
Cingulate cortex (cg)
Piriform cortex, L1 (pirl1)
Piriform cortex, L2 (pirl2)
Piriform cortex, L3 (pirl3)
Insular cortex (i)
Somatosensory cortex (s)
Retrosplenial granular cortex (rsg)
Parietal association cortex (p)
Entorhinal cortex (ent)
Visual cortex (v)
Olfactory bulb
Anterior olfactory nucleus (aon)
Granule cell layer (gro)
Internal plexiform layer (ipl)
Mitral cell layer (mi)
Glomerular layer (gl)
Rostral migratory stream (rms)
External plexiform layer (epl)
External plexiform layer of the accessory OB (epla)
Granule cell layer of the accessory OB (gra)
Glomerular layer of the accessory OB (gla)
Hippocampus
Polymorph layer of the dentate gyrus (podg)
Molecular layer of the dentate gyrus (modg)
Granular dentate gyrus (grdg)
CA1 - oriens layer (ca1or)
CA1 - pyramidal layer (ca1py)
CA1 - radiatum layer (ca1ra)
CA2 - oriens layer (ca2or)
CA2 - pyramidal layer (ca2py)
CA2 - radiatum layer (ca2ra)
CA3 - oriens layer (ca3or)
CA3 - pyramidal layer (ca3py)
CA3 - radiatum layer (ca3ra)
Stratum lucidum (slu)
Lacunosum moleculare (lmol)
Subiculum (sub)
Amygdala
Nucleus of the lateral olfactory tract (lot)
Basal medial amygdaloid nucleus (bma)
Basal lateral amygdala* (*bla) N/A
Basal lateral amygdaloid nucleus (bla)
Cortical amygdala (aco)
Central amygdala (ce)
Medial amygdaloid nucleus (mea)
Thalamus
Medial geniculate nucleus (mg)
Parafascicular thalamic nucleus (pf)
Pregeniculate nucleus (pg)
Stria terminalis (st)
Zona incerta (zi)
Anterodorsal thalamic nucleus (ad)
Reticular thalamic nucleus (rt)
Vental anterior thalamic nucleus (va)
Medial habenular nucleus (mhb)
Laterodorsal thalamic area (ld)
Paraventricular thalamic nucleus (pv)
Central medial thalamic area (cm)
Ventral lateral thalamic area (vl) N/A
Ventral medial thalamic area (vm)
Lateral habenulal nucleus (lhb)
Ventral posterior thalamus (vpt)
Anterior pretactal nucleus (apt)
Retromammillary nucleus (rm)
Hypothalamus
Dorsal tuberomammillary nucleus (dtm) N/A
Mammillary nucleus (mn) N/A
Periventricular hypothalamic nucleus (pe)
Supraoptic nucleus (so)
Tuberal nucleus (tu)
Ventral tuberomammillary nucleus (vtm) N/A
Lateral preoptic area (lpo)
Medial preoptic area (mpo)
Suprachiasmatic nucleus (sch)
Paraventricular hypothalamic nucleus (pa)
Anterior hypothalamic area, central (ahc)
Ventral medial hypothalamic nucleus (vmh)
Ventral medial hypothalamic nucleus* (*vmh) N/A
Arcuate nucleus (arc)
Arcuate nucleus* (*arc) N/A
Peduncular part of lateral hypothalmus (plh)
Dorsal medial hypothalamic nucleus (dm)
Stria terminalis* (*st) N/A
Cerebellum
Vestibulocerebellar nucleus (vecb) N/A
Moleuclar layer of the cerebellum (cemol)
Purkinje layer of the cerebellum (cepur)
Granular layer of the cerebellum (cegr)
Pons
Barrington's nucleus (bar) N/A
Koelliker-fuse nucleus (kf) N/A
Motor tregiminal nucleus (5n)
Parabrachial nucleus (pbp)
Principle sensory trigeminal nucleus (pr5)
Locus coeruleus (lc)
Pontine nucleus (pn)
Vestibular nucleus (ve)
Pontine reticular nucleus, oral (pno)
Lateral lemniscus (ll)
Superior paraolivary nucleus (spo)
Circumventricular organs
Subcommissural organ (sco)
Subfornical organ (sfo)
Median eminence (me)
Medulla (ap)

Antibodies in assayi
HPA075062

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The Human Protein Atlas

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