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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:282.1 nTPM
HPA:282.1 nTPM
GTEx:214.3 nTPM
FANTOM5:523.3 Scaled Tags Per Million
Pig:119.1 nTPM
Mouse:582.8 nTPM
Allen mouse:14.7 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 282.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 260.7
1833 Male, age 53, unknown 291.9
2411 Female, age 72, unknown 291.1
1830 Male, age 51, unknown 290.6
1870 Female, age 42, unknown 276.4
2828 Female, age 72, unknown 261.8
2019 Male, age 18, unknown 257.8
2586 Male, age 75, left hemisphere 240.8
1827 Male, age 72, unknown 236.0
2666 Male, age 74, left hemisphere 231.9
2219 Male, age 76, both hemispheres 228.9
Dorsal raphe nucleus
nTPM: 234.0
2750 Male, age 76, both hemispheres 274.5
2016 Female, age 72, unknown 241.7
1828 Male, age 53, unknown 230.5
2298 Female, age 72, unknown 216.0
2047 Male, age 72, unknown 207.1
Inferior colliculus
nTPM: 227.6
2849 Male, age 72, unknown 236.2
1848 Female, age 42, unknown 234.0
1890 Male, age 53, unknown 222.7
2097 Female, age 72, unknown 217.4
Median raphe nucleus
nTPM: 216.0
2220 Male, age 76, midline 216.0
Pedunculopontine tegmental nucleus
nTPM: 240.9
2334 Male, age 80, both hemispheres 252.5
1921 Female, age 85, both hemispheres 236.8
2338 Male, age 61, both hemispheres 233.3
Periaquaductal grey, anterior
nTPM: 220.4
2502 Female, age 75, unknown 228.1
1947 Male, age 18, unknown 222.4
1795 Male, age 51, unknown 210.8
Periaquaductal grey, dorsal
nTPM: 217.5
2464 Female, age 72, unknown 244.5
1831 Male, age 72, unknown 218.2
2850 Male, age 76, both hemispheres 204.5
1840 Male, age 53, unknown 203.0
Periaquaductal grey, lateral
nTPM: 220.3
2053 Male, age 18, unknown 230.3
2272 Male, age 74, both hemispheres 225.2
2140 Male, age 76, both hemispheres 205.4
Pretectal area
nTPM: 232.3
2316 Male, age 76, right hemisphere 261.4
1815 Male, age 53, unknown 258.6
2667 Female, age 75, unknown 246.3
2407 Male, age 75, both hemispheres 239.9
1817 Female, age 42, unknown 239.8
2825 Male, age 18, unknown 234.4
2273 Male, age 74, both hemispheres 224.1
2007 Male, age 72, unknown 223.5
2224 Female, age 72, unknown 219.3
1944 Female, age 72, unknown 204.5
1816 Male, age 51, unknown 203.8
Red nucleus
nTPM: 282.1
1904 Male, age 53, unknown 322.5
1821 Female, age 72, unknown 306.5
1865 Male, age 51, unknown 300.7
2823 Male, age 76, right hemisphere 296.5
2769 Male, age 72, unknown 293.1
2227 Male, age 72, unknown 292.9
2785 Male, age 18, unknown 284.3
1954 Female, age 42, unknown 282.4
2503 Female, age 72, unknown 276.3
2588 Male, age 74, left hemisphere 267.6
2725 Female, age 75, unknown 232.4
2584 Male, age 75, left hemisphere 230.1
Substantia nigra
nTPM: 234.7
2583 Male, age 75, right hemisphere 251.2
1851 Male, age 51, unknown 250.9
2699 Male, age 18, unknown 247.1
2409 Female, age 72, unknown 245.8
2590 Female, age 75, unknown 240.2
1889 Female, age 72, unknown 235.9
2665 Male, age 74, both hemispheres 224.2
2241 Male, age 72, unknown 221.0
1916 Female, age 42, unknown 217.1
1941 Male, age 53, unknown 213.8
Superior colliculus
nTPM: 250.6
1995 Male, age 72, unknown 306.7
1913 Female, age 42, unknown 288.3
1895 Male, age 76, right hemisphere 273.1
1839 Male, age 51, unknown 258.1
2668 Female, age 75, unknown 248.3
2587 Male, age 74, left hemisphere 246.2
1796 Male, age 53, unknown 240.6
2664 Male, age 75, both hemispheres 221.4
2087 Female, age 72, unknown 211.5
2261 Male, age 18, unknown 211.3
Ventral tegmental area
nTPM: 245.2
2223 Female, age 72, unknown 279.6
2410 Female, age 72, unknown 269.0
1915 Female, age 42, unknown 236.9
1942 Male, age 51, unknown 231.6
2218 Male, age 76, both hemispheres 228.6
2021 Male, age 53, unknown 225.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 214.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 214.3
Samples: 139

Max nTPM: 735.2
Min nTPM: 72.9
Std nTPM: 121.7
Median nTPM: 181.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 735.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 718.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 599.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 589.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 578.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 514.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 447.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 432.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 407.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 403.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 402.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 401.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 396.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 387.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 385.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 370.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 355.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 342.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 333.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 325.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 315.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 301.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 297.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 288.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 287.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 287.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 277.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 271.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 270.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 269.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 268.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 266.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 265.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 264.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 257.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 244.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 244.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 242.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 240.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 239.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 236.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 225.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 224.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 223.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 220.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 220.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 219.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 215.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 214.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 212.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 207.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 206.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 204.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 203.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 203.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 202.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 201.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 200.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 197.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 196.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 196.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 193.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 193.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 190.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 189.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 189.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 186.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 186.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 184.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 181.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 177.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 175.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 174.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 173.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 173.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 171.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 171.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 171.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 166.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 165.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 165.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 165.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 165.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 162.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 161.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 159.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 152.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 148.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 147.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 146.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 146.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 145.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 145.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 144.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 143.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 142.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 142.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 141.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 140.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 140.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 139.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 139.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 137.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 137.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 136.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 134.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 133.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 132.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 130.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 128.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 128.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 127.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 127.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 124.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 123.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 123.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 119.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 115.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 114.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 114.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 113.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 113.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 112.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 112.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 108.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 107.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 104.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 101.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 101.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 98.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 95.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 93.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 89.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 88.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 86.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 86.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 75.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 73.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 72.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 523.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 523.3
FF:10158-103A5 76 years, female 523.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 119.1
Pig sample Sample description nTPM
Midbrain
nTPM: 119.1
Samples: 4

Max nTPM: 306.2
Min nTPM: 39.3
Sample A Female 306.2
Sample B Female 87.5
Sample C Male 39.3
Sample D Male 43.2
Periaqueductal gray
nTPM: 54.0
Samples: 3

Max nTPM: 68.7
Min nTPM: 35.7
Sample B Female 57.5
Sample C Male 35.7
Sample D Male 68.7
Substantia nigra
nTPM: 106.0
Samples: 4

Max nTPM: 180.7
Min nTPM: 71.1
Sample A Female 95.3
Sample B Female 71.1
Sample C Male 77.0
Sample D Male 180.7
Superior colliculi
nTPM: 74.0
Samples: 4

Max nTPM: 102.3
Min nTPM: 37.7
Sample A Female 75.7
Sample B Female 37.7
Sample C Male 80.4
Sample D Male 102.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 582.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 582.8
Samples: 4

Max nTPM: 688.9
Min nTPM: 499.3
Sample A Male 503.5
Sample B Male 499.3
Sample C Female 688.9
Sample D Female 639.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 14.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 14.7
386243 Antisense, RP_040804_01_D04, Mouse strain C57BL/6J (56 days, male) 14.7

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