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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:31.7 nTPM
HPA:31.7 nTPM
GTEx:38.3 nTPM
FANTOM5:20.6 Scaled Tags Per Million
Pig:17.6 nTPM
Mouse:9.7 nTPM
Allen mouse:0.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 31.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 28.1
2586 Male, age 75, left hemisphere 33.0
2219 Male, age 76, both hemispheres 30.1
2666 Male, age 74, left hemisphere 28.9
1827 Male, age 72, unknown 28.6
2411 Female, age 72, unknown 28.4
2828 Female, age 72, unknown 27.5
1870 Female, age 42, unknown 26.9
1833 Male, age 53, unknown 26.5
2019 Male, age 18, unknown 25.6
1830 Male, age 51, unknown 25.5
Dorsal raphe nucleus
nTPM: 28.8
2298 Female, age 72, unknown 31.5
2047 Male, age 72, unknown 29.8
2750 Male, age 76, both hemispheres 28.5
1828 Male, age 53, unknown 27.3
2016 Female, age 72, unknown 26.9
Inferior colliculus
nTPM: 27.5
2097 Female, age 72, unknown 28.4
1848 Female, age 42, unknown 27.6
1890 Male, age 53, unknown 27.2
2849 Male, age 72, unknown 26.7
Median raphe nucleus
nTPM: 29.4
2220 Male, age 76, midline 29.4
Pedunculopontine tegmental nucleus
nTPM: 27.2
2334 Male, age 80, both hemispheres 28.4
1921 Female, age 85, both hemispheres 27.6
2338 Male, age 61, both hemispheres 25.5
Periaquaductal grey, anterior
nTPM: 31.7
1795 Male, age 51, unknown 32.4
1947 Male, age 18, unknown 31.7
2502 Female, age 75, unknown 31.1
Periaquaductal grey, dorsal
nTPM: 26.0
2464 Female, age 72, unknown 27.7
1840 Male, age 53, unknown 27.3
1831 Male, age 72, unknown 24.7
2850 Male, age 76, both hemispheres 24.2
Periaquaductal grey, lateral
nTPM: 26.3
2272 Male, age 74, both hemispheres 27.4
2053 Male, age 18, unknown 26.4
2140 Male, age 76, both hemispheres 25.1
Pretectal area
nTPM: 27.4
2007 Male, age 72, unknown 30.1
2825 Male, age 18, unknown 28.4
1816 Male, age 51, unknown 28.2
2407 Male, age 75, both hemispheres 28.2
1817 Female, age 42, unknown 27.3
1944 Female, age 72, unknown 27.1
2224 Female, age 72, unknown 27.0
2273 Male, age 74, both hemispheres 26.8
1815 Male, age 53, unknown 26.6
2316 Male, age 76, right hemisphere 26.3
2667 Female, age 75, unknown 25.5
Red nucleus
nTPM: 27.0
2584 Male, age 75, left hemisphere 28.7
2785 Male, age 18, unknown 28.4
2588 Male, age 74, left hemisphere 28.1
2227 Male, age 72, unknown 27.9
2769 Male, age 72, unknown 27.8
1954 Female, age 42, unknown 27.4
2503 Female, age 72, unknown 26.9
1904 Male, age 53, unknown 26.8
1821 Female, age 72, unknown 26.3
1865 Male, age 51, unknown 26.2
2823 Male, age 76, right hemisphere 25.0
2725 Female, age 75, unknown 24.8
Substantia nigra
nTPM: 28.6
1916 Female, age 42, unknown 30.9
1851 Male, age 51, unknown 30.7
2590 Female, age 75, unknown 29.6
1941 Male, age 53, unknown 29.5
2409 Female, age 72, unknown 28.9
2583 Male, age 75, right hemisphere 28.1
2665 Male, age 74, both hemispheres 27.9
2699 Male, age 18, unknown 26.9
2241 Male, age 72, unknown 26.7
1889 Female, age 72, unknown 26.6
Superior colliculus
nTPM: 27.7
2668 Female, age 75, unknown 32.1
1796 Male, age 53, unknown 29.8
2664 Male, age 75, both hemispheres 29.3
2261 Male, age 18, unknown 29.2
2087 Female, age 72, unknown 27.4
1839 Male, age 51, unknown 26.9
1895 Male, age 76, right hemisphere 25.8
1995 Male, age 72, unknown 25.8
2587 Male, age 74, left hemisphere 25.5
1913 Female, age 42, unknown 25.3
Ventral tegmental area
nTPM: 28.4
1915 Female, age 42, unknown 30.1
1942 Male, age 51, unknown 29.4
2410 Female, age 72, unknown 28.7
2021 Male, age 53, unknown 27.9
2223 Female, age 72, unknown 27.6
2218 Male, age 76, both hemispheres 26.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 38.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 38.3
Samples: 139

Max nTPM: 70.0
Min nTPM: 18.6
Std nTPM: 10.0
Median nTPM: 37.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 70.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 68.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 60.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 60.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 59.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 58.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 57.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 57.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 55.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 54.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 54.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 52.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 51.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 51.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 51.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 50.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 50.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 50.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 50.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 49.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 49.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 47.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 47.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 47.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 47.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 47.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 46.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 46.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 46.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 46.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 46.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 46.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 45.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 45.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 44.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 44.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 44.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 43.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 43.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 43.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 43.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 42.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 42.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 42.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 42.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 41.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 41.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 41.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 41.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 41.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 41.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 40.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 40.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 40.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 40.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 39.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 39.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 39.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 39.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 39.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 39.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 38.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 38.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 38.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 38.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 38.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 38.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 38.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 38.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 37.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 37.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 36.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 36.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 36.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 36.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 36.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 36.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 36.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 36.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 35.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 35.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 35.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 35.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 35.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 35.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 35.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 34.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 34.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 34.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 34.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 34.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 34.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 33.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 33.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 33.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 33.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 32.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 32.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 32.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 31.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 31.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 31.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 30.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 30.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 30.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 29.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 29.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 29.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 29.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 28.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 28.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 28.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 28.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 27.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 27.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 27.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 27.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 27.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 27.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 27.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 27.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 27.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 27.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 26.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 26.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 26.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 26.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 26.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 26.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 25.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 25.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 24.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 24.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 23.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 22.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 21.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 21.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 19.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 18.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 20.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 20.6
FF:10158-103A5 76 years, female 20.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 17.6
Pig sample Sample description nTPM
Midbrain
nTPM: 17.6
Samples: 4

Max nTPM: 26.2
Min nTPM: 13.6
Sample A Female 26.2
Sample B Female 16.0
Sample C Male 14.5
Sample D Male 13.6
Periaqueductal gray
nTPM: 13.4
Samples: 3

Max nTPM: 14.4
Min nTPM: 12.4
Sample B Female 14.4
Sample C Male 13.3
Sample D Male 12.4
Substantia nigra
nTPM: 16.0
Samples: 4

Max nTPM: 19.8
Min nTPM: 13.3
Sample A Female 15.7
Sample B Female 13.3
Sample C Male 15.3
Sample D Male 19.8
Superior colliculi
nTPM: 14.1
Samples: 4

Max nTPM: 15.5
Min nTPM: 10.8
Sample A Female 15.5
Sample B Female 10.8
Sample C Male 14.5
Sample D Male 15.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 9.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 9.7
Samples: 4

Max nTPM: 11.1
Min nTPM: 8.2
Sample A Male 11.1
Sample B Male 8.2
Sample C Female 9.1
Sample D Female 10.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.2
68638023 Antisense, RP_050126_02_A12, Mouse strain C57BL/6J (56 days, male) 0.2

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