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TISSUE MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM ENDOMETRIUM
EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MEDULLA OBLONGATA MIDBRAIN OVARY
PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PONS PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE SMOOTH MUSCLE
SPINAL CORD SPLEEN STOMACH TESTIS THALAMUS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA WHITE MATTER
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:60.8 nTPM
HPA:60.8 nTPM
GTEx:45.5 nTPM
FANTOM5:114.2 Scaled Tags Per Million
Pig:76.7 nTPM
Mouse:50.1 nTPM
Allen mouse:1.6 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 60.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 40.6
2828 Female, age 72, unknown 49.8
1870 Female, age 42, unknown 45.7
2586 Male, age 75, left hemisphere 45.4
2219 Male, age 76, both hemispheres 43.5
2666 Male, age 74, left hemisphere 40.6
1833 Male, age 53, unknown 40.4
1827 Male, age 72, unknown 39.9
2411 Female, age 72, unknown 38.5
1830 Male, age 51, unknown 37.2
2019 Male, age 18, unknown 24.6
Dorsal raphe nucleus
nTPM: 59.3
2047 Male, age 72, unknown 72.7
2016 Female, age 72, unknown 64.0
2298 Female, age 72, unknown 63.1
1828 Male, age 53, unknown 50.2
2750 Male, age 76, both hemispheres 46.5
Inferior colliculus
nTPM: 44.6
1848 Female, age 42, unknown 51.2
2849 Male, age 72, unknown 48.1
2097 Female, age 72, unknown 40.8
1890 Male, age 53, unknown 38.1
Median raphe nucleus
nTPM: 54.1
2220 Male, age 76, midline 54.1
Pedunculopontine tegmental nucleus
nTPM: 41.3
1921 Female, age 85, both hemispheres 46.7
2334 Male, age 80, both hemispheres 44.7
2338 Male, age 61, both hemispheres 32.6
Periaquaductal grey, anterior
nTPM: 54.9
1795 Male, age 51, unknown 60.4
1947 Male, age 18, unknown 57.9
2502 Female, age 75, unknown 46.4
Periaquaductal grey, dorsal
nTPM: 60.8
1840 Male, age 53, unknown 76.8
2850 Male, age 76, both hemispheres 67.7
2464 Female, age 72, unknown 51.0
1831 Male, age 72, unknown 47.9
Periaquaductal grey, lateral
nTPM: 58.9
2053 Male, age 18, unknown 59.8
2140 Male, age 76, both hemispheres 59.3
2272 Male, age 74, both hemispheres 57.7
Pretectal area
nTPM: 46.5
2273 Male, age 74, both hemispheres 70.3
2825 Male, age 18, unknown 65.3
2224 Female, age 72, unknown 64.9
2667 Female, age 75, unknown 47.9
2316 Male, age 76, right hemisphere 41.8
1944 Female, age 72, unknown 41.6
1817 Female, age 42, unknown 39.1
1815 Male, age 53, unknown 37.9
1816 Male, age 51, unknown 36.2
2407 Male, age 75, both hemispheres 35.9
2007 Male, age 72, unknown 30.4
Red nucleus
nTPM: 36.3
2725 Female, age 75, unknown 46.5
1954 Female, age 42, unknown 41.1
2227 Male, age 72, unknown 39.0
2503 Female, age 72, unknown 39.0
2769 Male, age 72, unknown 38.8
1821 Female, age 72, unknown 36.5
1865 Male, age 51, unknown 36.4
1904 Male, age 53, unknown 35.6
2823 Male, age 76, right hemisphere 33.5
2588 Male, age 74, left hemisphere 32.7
2584 Male, age 75, left hemisphere 28.4
2785 Male, age 18, unknown 28.2
Substantia nigra
nTPM: 38.3
2699 Male, age 18, unknown 62.0
1916 Female, age 42, unknown 40.7
1851 Male, age 51, unknown 39.4
1889 Female, age 72, unknown 37.0
2583 Male, age 75, right hemisphere 36.6
2241 Male, age 72, unknown 35.0
1941 Male, age 53, unknown 34.9
2409 Female, age 72, unknown 33.2
2590 Female, age 75, unknown 32.9
2665 Male, age 74, both hemispheres 31.1
Superior colliculus
nTPM: 44.9
1995 Male, age 72, unknown 55.5
2664 Male, age 75, both hemispheres 53.1
1796 Male, age 53, unknown 45.5
1839 Male, age 51, unknown 44.6
2587 Male, age 74, left hemisphere 44.0
2261 Male, age 18, unknown 42.5
1913 Female, age 42, unknown 42.4
2668 Female, age 75, unknown 41.8
2087 Female, age 72, unknown 40.5
1895 Male, age 76, right hemisphere 39.4
Ventral tegmental area
nTPM: 43.6
2021 Male, age 53, unknown 55.8
1942 Male, age 51, unknown 47.0
1915 Female, age 42, unknown 46.2
2218 Male, age 76, both hemispheres 40.7
2223 Female, age 72, unknown 38.1
2410 Female, age 72, unknown 34.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 45.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 45.5
Samples: 139

Max nTPM: 158.9
Min nTPM: 5.4
Std nTPM: 24.0
Median nTPM: 42.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 158.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 156.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 117.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 96.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 89.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 87.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 85.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 81.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 81.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 78.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 77.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 76.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 71.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 68.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 67.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 67.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 66.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 66.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 65.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 65.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 65.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 65.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 64.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 63.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 62.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 62.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 62.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 61.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 60.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 59.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 58.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 58.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 57.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 56.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 56.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 56.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 55.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 54.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 54.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 54.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 53.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 53.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 53.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 53.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 52.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 52.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 52.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 52.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 50.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 50.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 50.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 50.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 49.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 49.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 48.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 47.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 47.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 46.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 46.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 46.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 45.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 45.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 45.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 45.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 45.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 43.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 43.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 43.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 42.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 42.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 42.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 42.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 41.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 41.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 40.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 40.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 40.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 40.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 39.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 39.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 39.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 39.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 38.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 38.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 38.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 38.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 37.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 37.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 36.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 36.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 36.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 36.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 36.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 35.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 35.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 34.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 34.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 33.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 33.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 33.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 32.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 32.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 32.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 32.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 31.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 30.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 30.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 28.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 26.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 26.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 26.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 24.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 24.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 24.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 23.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 23.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 22.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 21.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 21.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 21.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 21.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 20.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 20.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 20.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 19.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 18.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 17.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 16.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 15.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 14.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 14.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 13.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 13.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 12.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 9.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 9.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 9.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 5.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 5.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 114.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 114.2
FF:10158-103A5 76 years, female 114.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 76.7
Pig sample Sample description nTPM
Midbrain
nTPM: 76.7
Samples: 4

Max nTPM: 131.0
Min nTPM: 44.6
Sample A Female 131.0
Sample B Female 44.6
Sample C Male 64.5
Sample D Male 66.6
Periaqueductal gray
nTPM: 71.2
Samples: 3

Max nTPM: 83.0
Min nTPM: 53.6
Sample B Female 53.6
Sample C Male 83.0
Sample D Male 76.9
Substantia nigra
nTPM: 62.6
Samples: 4

Max nTPM: 71.5
Min nTPM: 54.2
Sample A Female 71.5
Sample B Female 55.1
Sample C Male 54.2
Sample D Male 69.6
Superior colliculi
nTPM: 48.5
Samples: 4

Max nTPM: 66.8
Min nTPM: 29.8
Sample A Female 66.8
Sample B Female 29.8
Sample C Male 42.7
Sample D Male 54.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 50.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 50.1
Samples: 4

Max nTPM: 53.8
Min nTPM: 46.8
Sample A Male 46.8
Sample B Male 49.2
Sample C Female 53.8
Sample D Female 50.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 1.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.6
73497044 Antisense, RP_051019_04_B09, Mouse strain C57BL/6J (56 days, male) 3.2
74357547 Antisense, RP_051019_04_B09, Mouse strain C57BL/6J (56 days, male) 1.4
70794013 Antisense, RP_050712_01_B10, Mouse strain C57BL/6J (56 days, male) 0.0

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