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TISSUE MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM ENDOMETRIUM
EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MEDULLA OBLONGATA MIDBRAIN OVARY
PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PONS PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE SMOOTH MUSCLE
SPINAL CORD SPLEEN STOMACH TESTIS THALAMUS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA WHITE MATTER
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:255.8 nTPM
HPA:255.8 nTPM
GTEx:333.5 nTPM
FANTOM5:1498.7 Scaled Tags Per Million
Pig:327.7 nTPM
Mouse:372.0 nTPM
Allen mouse:5.5 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 255.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 235.4
2666 Male, age 74, left hemisphere 255.4
1870 Female, age 42, unknown 249.7
2019 Male, age 18, unknown 245.3
1830 Male, age 51, unknown 242.5
1833 Male, age 53, unknown 239.4
2586 Male, age 75, left hemisphere 238.5
1827 Male, age 72, unknown 230.0
2411 Female, age 72, unknown 229.5
2828 Female, age 72, unknown 220.1
2219 Male, age 76, both hemispheres 203.5
Dorsal raphe nucleus
nTPM: 221.2
2750 Male, age 76, both hemispheres 244.5
1828 Male, age 53, unknown 230.5
2047 Male, age 72, unknown 211.7
2016 Female, age 72, unknown 210.1
2298 Female, age 72, unknown 209.0
Inferior colliculus
nTPM: 219.3
2849 Male, age 72, unknown 231.9
2097 Female, age 72, unknown 219.4
1848 Female, age 42, unknown 213.4
1890 Male, age 53, unknown 212.5
Median raphe nucleus
nTPM: 247.1
2220 Male, age 76, midline 247.1
Pedunculopontine tegmental nucleus
nTPM: 228.3
2334 Male, age 80, both hemispheres 261.2
2338 Male, age 61, both hemispheres 215.6
1921 Female, age 85, both hemispheres 208.1
Periaquaductal grey, anterior
nTPM: 215.7
2502 Female, age 75, unknown 224.4
1947 Male, age 18, unknown 216.1
1795 Male, age 51, unknown 206.6
Periaquaductal grey, dorsal
nTPM: 212.5
2850 Male, age 76, both hemispheres 239.5
1831 Male, age 72, unknown 220.0
2464 Female, age 72, unknown 198.2
1840 Male, age 53, unknown 192.2
Periaquaductal grey, lateral
nTPM: 217.5
2053 Male, age 18, unknown 224.3
2140 Male, age 76, both hemispheres 222.8
2272 Male, age 74, both hemispheres 205.3
Pretectal area
nTPM: 229.6
1817 Female, age 42, unknown 264.3
1815 Male, age 53, unknown 257.0
2667 Female, age 75, unknown 238.9
2007 Male, age 72, unknown 234.8
2825 Male, age 18, unknown 231.9
1816 Male, age 51, unknown 231.8
2316 Male, age 76, right hemisphere 230.7
2407 Male, age 75, both hemispheres 213.2
2224 Female, age 72, unknown 209.3
1944 Female, age 72, unknown 208.4
2273 Male, age 74, both hemispheres 205.8
Red nucleus
nTPM: 255.8
1821 Female, age 72, unknown 302.3
2503 Female, age 72, unknown 263.4
1954 Female, age 42, unknown 261.0
1904 Male, age 53, unknown 260.6
2769 Male, age 72, unknown 259.5
1865 Male, age 51, unknown 257.8
2584 Male, age 75, left hemisphere 252.5
2227 Male, age 72, unknown 251.3
2823 Male, age 76, right hemisphere 241.4
2785 Male, age 18, unknown 241.1
2725 Female, age 75, unknown 241.0
2588 Male, age 74, left hemisphere 238.2
Substantia nigra
nTPM: 227.1
2665 Male, age 74, both hemispheres 251.5
1851 Male, age 51, unknown 239.1
1889 Female, age 72, unknown 233.9
2699 Male, age 18, unknown 233.2
1916 Female, age 42, unknown 230.5
2583 Male, age 75, right hemisphere 228.8
2590 Female, age 75, unknown 227.5
1941 Male, age 53, unknown 223.5
2241 Male, age 72, unknown 201.6
2409 Female, age 72, unknown 201.2
Superior colliculus
nTPM: 228.5
1913 Female, age 42, unknown 247.9
2587 Male, age 74, left hemisphere 246.1
1995 Male, age 72, unknown 241.0
1839 Male, age 51, unknown 235.7
1895 Male, age 76, right hemisphere 230.5
2664 Male, age 75, both hemispheres 224.5
2668 Female, age 75, unknown 220.2
1796 Male, age 53, unknown 218.0
2261 Male, age 18, unknown 213.2
2087 Female, age 72, unknown 207.7
Ventral tegmental area
nTPM: 231.5
2223 Female, age 72, unknown 284.5
2021 Male, age 53, unknown 227.9
2218 Male, age 76, both hemispheres 226.6
2410 Female, age 72, unknown 221.9
1915 Female, age 42, unknown 219.4
1942 Male, age 51, unknown 208.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 333.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 333.5
Samples: 139

Max nTPM: 758.6
Min nTPM: 183.8
Std nTPM: 90.4
Median nTPM: 316.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 758.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 608.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 518.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 515.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 513.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 502.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 499.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 492.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 489.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 486.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 481.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 474.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 469.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 467.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 461.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 448.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 447.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 446.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 441.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 428.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 423.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 422.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 412.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 412.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 410.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 408.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 408.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 407.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 400.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 399.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 393.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 389.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 386.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 383.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 383.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 383.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 375.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 373.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 371.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 369.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 365.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 364.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 363.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 363.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 361.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 356.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 350.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 350.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 345.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 345.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 344.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 343.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 343.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 340.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 338.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 338.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 336.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 335.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 333.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 330.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 330.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 330.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 328.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 327.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 324.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 324.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 320.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 319.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 317.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 316.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 316.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 315.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 315.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 311.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 309.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 309.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 307.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 307.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 305.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 304.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 304.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 303.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 302.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 300.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 299.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 299.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 299.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 298.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 293.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 290.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 286.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 286.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 286.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 285.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 284.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 283.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 283.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 280.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 277.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 276.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 275.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 274.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 272.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 271.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 269.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 268.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 266.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 264.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 264.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 260.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 259.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 259.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 257.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 257.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 256.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 255.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 255.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 253.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 251.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 250.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 245.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 241.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 239.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 236.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 233.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 232.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 232.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 225.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 224.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 221.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 215.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 215.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 208.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 200.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 199.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 199.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 194.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 186.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 183.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 1498.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 1498.7
FF:10158-103A5 76 years, female 1498.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 327.7
Pig sample Sample description nTPM
Midbrain
nTPM: 314.0
Samples: 4

Max nTPM: 456.8
Min nTPM: 242.8
Sample A Female 456.8
Sample B Female 301.3
Sample C Male 242.8
Sample D Male 254.9
Periaqueductal gray
nTPM: 254.5
Samples: 3

Max nTPM: 271.5
Min nTPM: 236.7
Sample B Female 255.4
Sample C Male 271.5
Sample D Male 236.7
Substantia nigra
nTPM: 307.0
Samples: 4

Max nTPM: 388.0
Min nTPM: 254.9
Sample A Female 388.0
Sample B Female 254.9
Sample C Male 290.9
Sample D Male 294.2
Superior colliculi
nTPM: 327.7
Samples: 4

Max nTPM: 424.5
Min nTPM: 279.6
Sample A Female 424.5
Sample B Female 320.5
Sample C Male 279.6
Sample D Male 286.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 372.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 372.1
Samples: 4

Max nTPM: 398.2
Min nTPM: 361.7
Sample A Male 398.2
Sample B Male 362.3
Sample C Female 361.7
Sample D Female 366.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 5.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 5.5
77791992 Antisense, RP_070208_04_C07, Mouse strain C57BL/6J (56 days, male) 6.0
67978400 Antisense, RP_040923_01_B01, Mouse strain C57BL/6J (56 days, male) 5.0

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