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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 22.4
Min nTPM: 5.2
Std nTPM: 3.6
Median nTPM:
490_1
67 years, female
22.4
162_1
79 years, female
21.2
149_1
88 years, male
21.1
491_1
89 years, female
20.8
142_1
61 years, female
20.1
89_1
63 years, male
19.0
117_1
61 years, male
18.9
32_1
67 years, male
18.4
43_1
64 years, female
18.2
415_1
77 years, female
17.5
119_1
70 years, female
17.1
466_1
57 years, female
16.8
495_1
57 years, female
16.6
81_1
67 years, male
16.3
99_1
64 years, male
15.3
137_1
83 years, male
15.1
307_1
66 years, female
15.0
42_1
85 years, male
14.8
139_1
64 years, female
14.8
9_1
66 years, female
14.5
413_1
59 years, female
14.3
145_1
84 years, male
14.2
518_1
75 years, female
14.0
6_1
73 years, female
13.9
120_1
70 years, female
13.9
501_1
88 years, male
13.8
35_1
74 years, female
13.4
308_1
70 years, female
13.4
126_1
63 years, male
13.3
4_1
88 years, female
13.0
17_1
71 years, male
13.0
18_1
88 years, male
13.0
315_1
62 years, female
12.9
109_1
81 years, female
12.8
468_1
89 years, male
12.6
2_1
77 years, female
12.5
266_1
85 years, male
12.5
313_1
79 years, female
12.5
217_1
76 years, male
12.3
324_1
76 years, male
12.3
396_1
62 years, male
12.3
414_1
84 years, female
12.1
153_1
70 years, female
12.0
348_1
84 years, male
12.0
499_1
55 years, female
12.0
265_1
87 years, male
11.9
347_1
72 years, male
11.8
526_1
61 years, male
11.7
447_1
81 years, male
11.6
115_1
83 years, male
11.5
311_1
78 years, male
11.5
375_1
74 years, female
11.5
254_1
77 years, female
11.4
314_1
67 years, male
11.3
322_1
76 years, male
11.1
389_1
86 years, female
11.1
355_1
70 years, female
11.0
288_1
66 years, female
10.9
316_1
62 years, male
10.9
386_1
76 years, male
10.8
291_1
76 years, male
10.7
41_1
94 years, female
10.5
405_1
91 years, male
10.5
173_1
67 years, male
10.4
517_1
88 years, male
10.1
480_1
63 years, male
9.9
286_1
68 years, female
9.7
246_1
77 years, male
9.5
251_1
78 years, male
9.5
335_1
73 years, female
9.5
379_1
60 years, male
9.4
404_1
82 years, female
9.4
503_1
68 years, male
9.4
229_1
69 years, female
9.3
317_1
60 years, male
9.2
237_1
82 years, male
9.1
354_1
81 years, female
9.1
264_1
73 years, female
8.9
243_1
75 years, male
8.8
292_1
71 years, male
8.8
318_1
68 years, male
8.8
425_1
59 years, female
8.8
350_1
84 years, female
8.7
349_1
83 years, male
8.6
352_1
62 years, male
8.6
295_1
61 years, female
8.4
172_1
72 years, female
8.3
293_1
68 years, female
8.3
506_1
65 years, male
8.2
319_1
81 years, male
8.1
356_1
87 years, female
8.0
376_1
75 years, female
8.0
189_1
76 years, male
7.9
320_1
89 years, female
7.8
351_1
91 years, male
7.8
406_1
79 years, male
7.8
218_1
71 years, female
7.7
353_1
82 years, female
7.6
394_1
75 years, female
7.6
377_1
82 years, female
7.4
321_1
62 years, female
7.2
384_1
83 years, male
7.1
452_1
88 years, female
6.4
177_1
74 years, male
6.3
163_1
78 years, male
5.2
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
