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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:80.3 nTPM
HPA:80.3 nTPM
GTEx:64.6 nTPM
FANTOM5:71.6 Scaled Tags Per Million
Pig:66.0 nTPM
Mouse:114.7 nTPM
Allen mouse:7.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 80.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 65.4
2586 Male, age 75, left hemisphere 90.1
2019 Male, age 18, unknown 67.9
2828 Female, age 72, unknown 67.5
2666 Male, age 74, left hemisphere 64.3
1827 Male, age 72, unknown 64.1
2219 Male, age 76, both hemispheres 63.4
2411 Female, age 72, unknown 62.0
1830 Male, age 51, unknown 59.4
1833 Male, age 53, unknown 59.1
1870 Female, age 42, unknown 56.4
Dorsal raphe nucleus
nTPM: 54.7
1828 Male, age 53, unknown 61.7
2750 Male, age 76, both hemispheres 57.4
2047 Male, age 72, unknown 57.2
2298 Female, age 72, unknown 48.8
2016 Female, age 72, unknown 48.3
Inferior colliculus
nTPM: 54.6
1848 Female, age 42, unknown 58.3
2849 Male, age 72, unknown 57.6
1890 Male, age 53, unknown 52.9
2097 Female, age 72, unknown 49.5
Median raphe nucleus
nTPM: 50.4
2220 Male, age 76, midline 50.4
Pedunculopontine tegmental nucleus
nTPM: 53.7
1921 Female, age 85, both hemispheres 58.4
2334 Male, age 80, both hemispheres 54.3
2338 Male, age 61, both hemispheres 48.5
Periaquaductal grey, anterior
nTPM: 65.1
2502 Female, age 75, unknown 76.7
1947 Male, age 18, unknown 60.5
1795 Male, age 51, unknown 58.1
Periaquaductal grey, dorsal
nTPM: 47.8
2464 Female, age 72, unknown 60.2
1840 Male, age 53, unknown 51.8
1831 Male, age 72, unknown 43.8
2850 Male, age 76, both hemispheres 35.5
Periaquaductal grey, lateral
nTPM: 42.2
2053 Male, age 18, unknown 47.7
2140 Male, age 76, both hemispheres 40.9
2272 Male, age 74, both hemispheres 38.1
Pretectal area
nTPM: 61.4
1944 Female, age 72, unknown 80.5
1816 Male, age 51, unknown 75.5
2007 Male, age 72, unknown 73.6
2667 Female, age 75, unknown 72.6
1817 Female, age 42, unknown 63.2
1815 Male, age 53, unknown 61.5
2407 Male, age 75, both hemispheres 59.2
2825 Male, age 18, unknown 54.8
2316 Male, age 76, right hemisphere 49.5
2224 Female, age 72, unknown 49.3
2273 Male, age 74, both hemispheres 35.4
Red nucleus
nTPM: 62.4
2588 Male, age 74, left hemisphere 71.1
2584 Male, age 75, left hemisphere 68.2
2823 Male, age 76, right hemisphere 67.7
2769 Male, age 72, unknown 64.6
2785 Male, age 18, unknown 63.6
2227 Male, age 72, unknown 63.3
1865 Male, age 51, unknown 61.7
1904 Male, age 53, unknown 61.1
2503 Female, age 72, unknown 60.0
1821 Female, age 72, unknown 59.7
1954 Female, age 42, unknown 58.5
2725 Female, age 75, unknown 49.8
Substantia nigra
nTPM: 80.3
1916 Female, age 42, unknown 118.3
1941 Male, age 53, unknown 91.3
2665 Male, age 74, both hemispheres 87.9
1851 Male, age 51, unknown 85.6
2241 Male, age 72, unknown 75.4
2699 Male, age 18, unknown 75.1
2409 Female, age 72, unknown 74.5
2583 Male, age 75, right hemisphere 69.6
1889 Female, age 72, unknown 67.7
2590 Female, age 75, unknown 58.2
Superior colliculus
nTPM: 61.9
2087 Female, age 72, unknown 77.8
2664 Male, age 75, both hemispheres 72.8
2668 Female, age 75, unknown 72.3
1895 Male, age 76, right hemisphere 64.1
2261 Male, age 18, unknown 62.9
1796 Male, age 53, unknown 60.9
1839 Male, age 51, unknown 56.7
1913 Female, age 42, unknown 51.7
2587 Male, age 74, left hemisphere 51.7
1995 Male, age 72, unknown 48.5
Ventral tegmental area
nTPM: 65.0
1915 Female, age 42, unknown 80.9
2410 Female, age 72, unknown 77.5
2218 Male, age 76, both hemispheres 69.9
1942 Male, age 51, unknown 62.2
2021 Male, age 53, unknown 50.1
2223 Female, age 72, unknown 49.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 64.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 64.6
Samples: 139

Max nTPM: 134.9
Min nTPM: 28.0
Std nTPM: 19.9
Median nTPM: 63.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 134.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 126.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 121.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 113.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 109.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 103.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 96.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 95.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 94.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 94.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 93.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 93.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 91.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 91.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 89.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 88.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 88.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 87.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 87.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 86.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 84.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 83.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 82.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 81.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 81.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 79.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 78.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 77.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 77.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 77.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 77.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 76.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 76.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 75.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 75.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 75.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 74.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 74.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 74.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 73.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 73.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 73.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 73.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 72.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 72.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 72.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 72.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 71.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 70.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 70.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 69.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 69.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 69.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 69.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 69.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 68.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 67.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 67.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 66.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 65.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 65.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 65.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 64.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 64.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 64.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 64.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 64.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 64.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 63.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 63.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 63.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 62.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 61.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 61.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 61.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 61.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 61.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 61.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 61.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 61.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 61.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 60.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 59.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 58.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 58.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 58.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 58.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 58.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 57.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 56.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 55.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 55.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 54.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 53.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 53.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 53.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 53.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 53.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 52.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 52.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 52.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 52.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 51.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 50.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 50.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 50.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 50.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 49.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 49.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 49.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 46.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 45.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 45.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 44.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 44.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 43.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 43.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 42.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 41.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 41.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 41.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 41.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 41.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 40.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 39.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 39.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 39.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 38.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 38.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 38.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 38.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 38.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 35.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 32.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 32.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 31.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 31.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 30.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 28.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 71.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 71.6
FF:10158-103A5 76 years, female 71.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 66.0
Pig sample Sample description nTPM
Midbrain
nTPM: 61.1
Samples: 4

Max nTPM: 93.0
Min nTPM: 39.0
Sample A Female 39.0
Sample B Female 46.9
Sample C Male 93.0
Sample D Male 65.3
Periaqueductal gray
nTPM: 46.7
Samples: 3

Max nTPM: 56.3
Min nTPM: 40.8
Sample B Female 43.1
Sample C Male 56.3
Sample D Male 40.8
Substantia nigra
nTPM: 61.3
Samples: 4

Max nTPM: 86.2
Min nTPM: 40.4
Sample A Female 72.6
Sample B Female 40.4
Sample C Male 86.2
Sample D Male 45.8
Superior colliculi
nTPM: 66.0
Samples: 4

Max nTPM: 89.6
Min nTPM: 41.2
Sample A Female 59.4
Sample B Female 41.2
Sample C Male 89.6
Sample D Male 73.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 114.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 114.7
Samples: 4

Max nTPM: 121.2
Min nTPM: 112.4
Sample A Male 112.4
Sample B Male 112.4
Sample C Female 121.2
Sample D Female 112.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 7.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 7.9
74749970 Antisense, RP_060220_04_F08, Mouse strain C57BL/6J (56 days, male) 8.1
70191937 Antisense, RP_050512_04_H08, Mouse strain C57BL/6J (56 days, male) 7.7

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