Expression of RPS27 in glioma - The Human Protein Atlas

GLIOMA - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

RPS27 is not prognostic in glioma

Stage:

Survival analysis

Current cut offⁱ :

Best expression cut offⁱ : 576.73

Median expressionⁱ : N/A

Median follow up timeⁱ : N/A

P scoreⁱ N/A

3-year survival highⁱ N/A

3-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

518.2

Number of samples

153

Samples

Sample	Description	FPKM
TCGA-06-2569-01A	24 years, female, black or african american, alive, 13 days	1687.4
TCGA-14-0871-01A	75 years, female, white, dead, 880 days	1547.0
TCGA-14-0817-01A	69 years, female, white, dead, 164 days	1281.2
TCGA-02-2483-01A	43 years, male, asian, alive, 466 days	1176.7
TCGA-06-5417-01A	45 years, female, white, alive, 155 days	1146.3
TCGA-28-5218-01A	63 years, male, white, dead, 157 days	1084.3
TCGA-41-5651-01A	59 years, female, black or african american, dead, 460 days	987.0
TCGA-32-5222-01A	66 years, male, white, dead, 585 days	982.0
TCGA-14-1829-01A	57 years, male, black or african american, alive, 218 days	965.0
TCGA-14-1823-01A	58 years, female, white, dead, 543 days	956.8
TCGA-14-2554-01A	52 years, female, white, dead, 532 days	952.8
TCGA-27-1831-01A	66 years, male, white, dead, 505 days	939.2
TCGA-19-4065-01A	36 years, male, white, alive, 214 days	891.8
TCGA-27-2524-01A	56 years, male, white, dead, 231 days	861.3
TCGA-02-2486-01A	64 years, male, white, dead, 618 days	844.9
TCGA-27-2521-01A	34 years, male, white, dead, 510 days	826.5
TCGA-06-0178-01A	39 years, male, white, dead, 2681 days	818.4
TCGA-27-2526-01A	79 years, female, white, dead, 87 days	816.8
TCGA-12-3652-01A	60 years, male, white, dead, 1062 days	757.2
TCGA-06-0138-01A	43 years, male, white, dead, 737 days	746.6
TCGA-02-0055-01A	62 years, female, white, dead, 76 days	732.8
TCGA-76-4928-01B	85 years, female, white, dead, 94 days	730.8
TCGA-06-5416-01A	23 years, female, white, alive, 204 days	724.9
TCGA-12-5295-01A	60 years, female, white, dead, 454 days	718.3
TCGA-28-5213-01A	72 years, male, white, alive, 951 days	717.1
TCGA-12-0616-01A	36 years, female, white, dead, 448 days	712.6
TCGA-06-0744-01A	67 years, male, white, dead, 1426 days	702.7
TCGA-06-0238-01A	46 years, male, white, dead, 405 days	672.3
TCGA-26-5133-01A	59 years, male, white, alive, 452 days	661.6
TCGA-12-5299-01A	56 years, female, white, dead, 98 days	648.3
TCGA-28-5216-01A	52 years, male, white, alive, 415 days	646.7
TCGA-27-2528-01A	62 years, male, white, dead, 480 days	644.4
TCGA-06-0139-01A	40 years, male, white, dead, 362 days	643.7
TCGA-76-4932-01A	50 years, female, white, dead, 1458 days	637.8
TCGA-28-5207-01A	71 years, male, white, dead, 343 days	631.0
TCGA-06-0745-01A	59 years, male, white, dead, 239 days	623.3
TCGA-32-4213-01A	47 years, female, white, alive, 604 days	611.5
TCGA-12-1597-01B	62 years, female, white, dead, 675 days	609.9
TCGA-32-1982-01A	76 years, female, white, dead, 142 days	599.0
TCGA-06-2570-01A	21 years, female, white, alive, 958 days	585.9
TCGA-02-2485-01A	53 years, male, black or african american, alive, 470 days	577.8
TCGA-76-4925-01A	76 years, male, white, dead, 146 days	575.7
TCGA-41-2571-01A	89 years, male, white, dead, 26 days	574.5
TCGA-06-0210-01A	72 years, female, white, dead, 225 days	565.1
TCGA-06-5413-01A	67 years, male, white, alive, 268 days	562.6
TCGA-06-0219-01A	67 years, male, white, dead, 22 days	562.2
TCGA-06-0168-01A	59 years, female, white, dead, 598 days	557.6
TCGA-14-0787-01A	69 years, male, asian, dead, 68 days	557.6
TCGA-06-0649-01B	73 years, female, black or african american, dead, 64 days	548.1
TCGA-28-2509-01A	77 years, female, white, alive, 145 days	544.9
TCGA-19-5960-01A	56 years, male, white, dead, 455 days	541.4
TCGA-06-5412-01A	78 years, female, white, dead, 138 days	535.0
TCGA-06-5418-01A	75 years, female, white, dead, 83 days	530.4
TCGA-28-5208-01A	52 years, male, white, dead, 544 days	526.2
TCGA-06-0184-01A	63 years, male, white, dead, 2126 days	525.9
TCGA-06-0749-01A	50 years, male, black or african american, dead, 82 days	525.4
TCGA-06-5410-01A	72 years, female, white, dead, 108 days	515.2
TCGA-06-2563-01A	72 years, female, white, alive, 932 days	506.7
TCGA-26-1442-01A	43 years, male, white, alive, 953 days	506.7
TCGA-06-0645-01A	56 years, female, white, dead, 175 days	506.6
TCGA-06-5856-01A	58 years, male, white, dead, 114 days	504.4
TCGA-28-5204-01A	72 years, male, white, dead, 454 days	497.9
TCGA-12-0821-01A	62 years, male, white, dead, 323 days	497.1
TCGA-19-2625-01A	76 years, female, white, dead, 124 days	491.4
TCGA-06-0750-01A	43 years, male, white, dead, 28 days	480.9
TCGA-76-4927-01A	58 years, male, white, dead, 535 days	478.5
TCGA-32-2634-01A	82 years, male, white, alive, 693 days	475.1
TCGA-41-3915-01A	48 years, male, white, dead, 360 days	473.1
TCGA-19-2620-01A	70 years, male, white, dead, 148 days	472.6
TCGA-32-1980-01A	72 years, male, white, dead, 36 days	470.8
TCGA-32-2615-01A	62 years, male, white, dead, 485 days	470.1
TCGA-14-0789-01A	54 years, male, white, dead, 342 days	467.1
TCGA-06-0190-01A	62 years, male, white, dead, 317 days	462.3
TCGA-28-5220-01A	67 years, male, white, dead, 388 days	461.8
TCGA-06-2557-01A	76 years, male, black or african american, dead, 33 days	458.5
TCGA-06-5408-01A	54 years, female, white, dead, 357 days	448.3
TCGA-06-0141-01A	62 years, male, white, dead, 313 days	447.7
TCGA-27-1830-01A	57 years, male, white, dead, 154 days	447.4
TCGA-06-2558-01A	75 years, female, white, dead, 380 days	444.4
TCGA-14-1825-01A	70 years, male, white, dead, 232 days	443.0
TCGA-06-0130-01A	54 years, male, white, dead, 394 days	442.2
TCGA-06-0132-01A	49 years, male, white, dead, 771 days	435.7
TCGA-28-2499-01A	59 years, male, white, dead, 95 days	433.8
TCGA-15-0742-01A	65 years, male, white, dead, 419 days	428.6
TCGA-06-0686-01A	53 years, male, white, dead, 432 days	427.7
TCGA-27-1834-01A	56 years, male, white, dead, 1233 days	423.7
TCGA-26-5132-01A	74 years, male, white, alive, 286 days	422.7
TCGA-06-2565-01A	59 years, male, asian, dead, 506 days	422.4
TCGA-06-5414-01A	61 years, male, white, alive, 273 days	422.0
TCGA-41-2572-01A	67 years, male, white, dead, 406 days	421.4
TCGA-12-3650-01A	46 years, male, white, dead, 333 days	420.3
TCGA-14-0781-01B	49 years, male, black or african american, dead, 29 days	415.4
TCGA-06-0743-01A	69 years, male, white, dead, 803 days	413.6
TCGA-26-5135-01A	72 years, female, white, dead, 270 days	413.4
TCGA-14-1034-01A	60 years, female, dead, 485 days	413.1
TCGA-06-2559-01A	83 years, male, white, dead, 150 days	412.8
TCGA-06-5411-01A	51 years, male, white, dead, 254 days	412.5
TCGA-28-2513-01A	69 years, female, white, alive, 222 days	408.5
TCGA-06-0882-01A	30 years, male, white, dead, 632 days	408.5
TCGA-16-1045-01B	49 years, female, white, dead, 883 days	400.3
TCGA-19-2619-01A	55 years, female, black or african american, alive, 294 days	396.4
TCGA-16-0846-01A	85 years, male, white, dead, 119 days	395.0
TCGA-28-5209-01A	66 years, female, white, alive, 77 days	394.9
TCGA-19-2629-01A	60 years, male, white, dead, 737 days	390.9
TCGA-12-0619-01A	60 years, male, white, dead, 1062 days	390.6
TCGA-32-2638-01A	67 years, male, white, dead, 766 days	388.6
TCGA-06-0129-01A	30 years, male, asian, dead, 1024 days	388.3
TCGA-76-4926-01B	68 years, male, white, dead, 138 days	385.4
TCGA-32-2632-01A	80 years, male, white, dead, 269 days	380.6
TCGA-14-0790-01B	64 years, female, white, dead, 419 days	377.5
TCGA-76-4931-01A	70 years, female, white, dead, 279 days	376.5
TCGA-06-0174-01A	54 years, male, white, dead, 98 days	374.4
TCGA-27-2523-01A	63 years, male, white, dead, 489 days	374.2
TCGA-27-1837-01A	36 years, male, white, dead, 427 days	373.9
TCGA-27-2519-01A	48 years, male, white, dead, 550 days	369.4
TCGA-06-0644-01A	71 years, male, black or african american, dead, 384 days	368.2
TCGA-27-1835-01A	53 years, female, white, dead, 648 days	354.7
TCGA-12-3653-01A	34 years, female, white, dead, 442 days	353.0
TCGA-28-1747-01C	44 years, male, white, dead, 77 days	350.6
TCGA-06-5859-01A	63 years, male, white, alive, 139 days	347.6
TCGA-15-1444-01A	21 years, male, white, dead, 1537 days	344.1
TCGA-26-5139-01A	65 years, female, white, alive, 48 days	342.5
TCGA-27-1832-01A	59 years, female, white, dead, 300 days	341.4
TCGA-06-0747-01A	53 years, male, white, dead, 82 days	339.9
TCGA-06-2567-01A	65 years, male, white, dead, 133 days	330.5
TCGA-06-2562-01A	81 years, male, white, dead, 382 days	328.9
TCGA-06-5858-01A	45 years, female, white, alive, 187 days	328.2
TCGA-32-2616-01A	48 years, female, white, dead, 224 days	324.0
TCGA-06-0211-01B	47 years, male, white, dead, 360 days	323.7
TCGA-06-2561-01A	53 years, female, white, dead, 537 days	322.3
TCGA-12-0618-01A	49 years, male, white, dead, 395 days	322.0
TCGA-06-0156-01A	57 years, male, white, dead, 178 days	321.7
TCGA-06-2564-01A	50 years, male, white, alive, 181 days	321.3
TCGA-06-0125-01A	63 years, female, white, dead, 1448 days	317.7
TCGA-19-1787-01B	49 years, male, white, dead, 385 days	312.6
TCGA-26-5136-01B	78 years, female, white, dead, 577 days	309.0
TCGA-32-1970-01A	59 years, male, white, dead, 468 days	302.8
TCGA-06-0878-01A	74 years, male, white, alive, 218 days	301.4
TCGA-08-0386-01A	74 years, male, white, dead, 548 days	284.5
TCGA-28-1753-01A	53 years, male, white, alive, 37 days	282.3
TCGA-28-5215-01A	62 years, female, white, dead, 335 days	279.8
TCGA-06-0158-01A	73 years, male, white, dead, 329 days	279.7
TCGA-26-5134-01A	74 years, male, white, alive, 167 days	277.8
TCGA-19-2624-01A	51 years, male, white, dead, 5 days	276.6
TCGA-28-2514-01A	45 years, male, asian, alive, 160 days	259.6
TCGA-41-4097-01A	63 years, female, white, dead, 6 days	256.0
TCGA-06-0187-01A	69 years, male, white, dead, 828 days	252.8
TCGA-06-0646-01A	61 years, male, white, dead, 175 days	247.0
TCGA-76-4929-01A	76 years, female, white, dead, 111 days	246.4
TCGA-06-0157-01A	63 years, female, white, dead, 97 days	227.5
TCGA-02-0047-01A	78 years, male, white, dead, 448 days	207.7
TCGA-19-1390-01A	63 years, female, white, dead, 772 days	202.2
TCGA-06-1804-01A	81 years, female, white, dead, 414 days	180.1
Show allShow less

GLIOMA - Protein expressionⁱ

Pending cancer tissue analysis