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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:96.9 nTPM
HPA:96.9 nTPM
GTEx:99.7 nTPM
FANTOM5:42.6 Scaled Tags Per Million
Pig:118.7 nTPM
Mouse:167.8 nTPM
Allen mouse:13.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 96.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 92.4
2019 Male, age 18, unknown 107.8
2586 Male, age 75, left hemisphere 98.3
2411 Female, age 72, unknown 96.4
1827 Male, age 72, unknown 95.1
2828 Female, age 72, unknown 91.9
2219 Male, age 76, both hemispheres 90.6
1833 Male, age 53, unknown 87.9
1830 Male, age 51, unknown 86.0
1870 Female, age 42, unknown 85.7
2666 Male, age 74, left hemisphere 84.3
Dorsal raphe nucleus
nTPM: 91.5
2298 Female, age 72, unknown 98.9
1828 Male, age 53, unknown 96.4
2047 Male, age 72, unknown 92.3
2750 Male, age 76, both hemispheres 86.4
2016 Female, age 72, unknown 83.7
Inferior colliculus
nTPM: 93.1
2097 Female, age 72, unknown 100.5
1890 Male, age 53, unknown 95.4
1848 Female, age 42, unknown 91.3
2849 Male, age 72, unknown 85.0
Median raphe nucleus
nTPM: 83.9
2220 Male, age 76, midline 83.9
Pedunculopontine tegmental nucleus
nTPM: 88.0
1921 Female, age 85, both hemispheres 92.6
2334 Male, age 80, both hemispheres 90.8
2338 Male, age 61, both hemispheres 80.6
Periaquaductal grey, anterior
nTPM: 90.1
1947 Male, age 18, unknown 90.5
1795 Male, age 51, unknown 90.3
2502 Female, age 75, unknown 89.5
Periaquaductal grey, dorsal
nTPM: 83.0
2464 Female, age 72, unknown 85.4
1831 Male, age 72, unknown 83.0
1840 Male, age 53, unknown 82.5
2850 Male, age 76, both hemispheres 81.3
Periaquaductal grey, lateral
nTPM: 84.8
2272 Male, age 74, both hemispheres 90.6
2053 Male, age 18, unknown 82.1
2140 Male, age 76, both hemispheres 81.8
Pretectal area
nTPM: 95.9
2007 Male, age 72, unknown 112.1
1817 Female, age 42, unknown 109.2
1816 Male, age 51, unknown 104.4
1944 Female, age 72, unknown 102.5
2667 Female, age 75, unknown 102.3
1815 Male, age 53, unknown 97.0
2273 Male, age 74, both hemispheres 93.0
2224 Female, age 72, unknown 86.4
2316 Male, age 76, right hemisphere 83.4
2407 Male, age 75, both hemispheres 83.2
2825 Male, age 18, unknown 81.5
Red nucleus
nTPM: 94.8
2785 Male, age 18, unknown 103.5
1821 Female, age 72, unknown 102.2
2503 Female, age 72, unknown 101.2
2725 Female, age 75, unknown 96.0
1954 Female, age 42, unknown 94.2
2769 Male, age 72, unknown 94.0
1865 Male, age 51, unknown 93.3
1904 Male, age 53, unknown 92.8
2588 Male, age 74, left hemisphere 92.6
2227 Male, age 72, unknown 92.4
2823 Male, age 76, right hemisphere 91.3
2584 Male, age 75, left hemisphere 83.5
Substantia nigra
nTPM: 96.9
1916 Female, age 42, unknown 116.4
1889 Female, age 72, unknown 104.3
1851 Male, age 51, unknown 102.7
1941 Male, age 53, unknown 101.4
2665 Male, age 74, both hemispheres 95.2
2583 Male, age 75, right hemisphere 91.2
2699 Male, age 18, unknown 91.0
2241 Male, age 72, unknown 90.5
2409 Female, age 72, unknown 89.8
2590 Female, age 75, unknown 86.7
Superior colliculus
nTPM: 89.7
2087 Female, age 72, unknown 97.2
1796 Male, age 53, unknown 94.1
2668 Female, age 75, unknown 91.5
1895 Male, age 76, right hemisphere 91.0
2261 Male, age 18, unknown 90.7
2587 Male, age 74, left hemisphere 88.2
1995 Male, age 72, unknown 87.8
1839 Male, age 51, unknown 87.4
1913 Female, age 42, unknown 86.0
2664 Male, age 75, both hemispheres 83.3
Ventral tegmental area
nTPM: 93.6
2410 Female, age 72, unknown 110.1
1915 Female, age 42, unknown 100.5
2218 Male, age 76, both hemispheres 95.0
1942 Male, age 51, unknown 88.3
2223 Female, age 72, unknown 86.0
2021 Male, age 53, unknown 81.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 99.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 99.7
Samples: 139

Max nTPM: 170.0
Min nTPM: 41.9
Std nTPM: 24.9
Median nTPM: 98.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 170.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 169.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 160.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 153.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 150.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 147.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 144.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 143.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 142.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 141.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 141.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 139.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 138.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 132.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 131.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 131.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 130.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 129.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 129.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 129.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 127.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 126.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 126.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 125.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 125.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 123.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 123.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 121.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 121.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 120.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 120.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 118.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 118.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 115.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 113.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 112.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 112.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 112.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 111.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 110.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 109.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 109.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 109.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 108.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 108.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 107.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 106.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 106.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 104.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 104.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 104.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 103.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 102.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 101.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 101.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 101.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 101.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 100.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 99.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 99.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 99.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 98.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 98.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 98.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 98.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 98.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 98.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 98.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 98.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 98.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 97.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 97.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 96.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 96.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 95.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 95.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 95.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 95.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 94.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 94.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 94.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 93.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 92.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 92.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 91.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 91.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 90.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 89.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 89.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 89.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 89.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 88.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 88.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 87.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 87.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 87.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 87.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 86.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 85.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 85.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 85.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 84.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 84.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 84.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 84.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 84.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 82.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 80.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 80.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 80.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 80.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 78.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 77.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 76.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 76.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 75.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 75.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 73.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 72.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 72.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 71.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 71.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 70.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 70.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 68.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 68.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 67.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 67.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 67.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 65.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 64.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 61.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 60.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 60.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 60.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 58.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 55.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 50.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 41.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 42.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 42.6
FF:10158-103A5 76 years, female 42.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 118.7
Pig sample Sample description nTPM
Midbrain
nTPM: 104.6
Samples: 4

Max nTPM: 122.1
Min nTPM: 84.2
Sample A Female 99.2
Sample B Female 84.2
Sample C Male 122.1
Sample D Male 112.8
Periaqueductal gray
nTPM: 77.4
Samples: 3

Max nTPM: 89.6
Min nTPM: 67.4
Sample B Female 75.1
Sample C Male 89.6
Sample D Male 67.4
Substantia nigra
nTPM: 94.8
Samples: 4

Max nTPM: 133.7
Min nTPM: 71.5
Sample A Female 133.7
Sample B Female 71.5
Sample C Male 99.6
Sample D Male 74.5
Superior colliculi
nTPM: 118.7
Samples: 4

Max nTPM: 153.5
Min nTPM: 79.3
Sample A Female 153.5
Sample B Female 79.3
Sample C Male 135.9
Sample D Male 106.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 167.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 167.8
Samples: 4

Max nTPM: 176.5
Min nTPM: 157.2
Sample A Male 175.9
Sample B Male 157.2
Sample C Female 161.6
Sample D Female 176.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 13.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 13.8
357103 Antisense, RP_040617_02_B10, Mouse strain C57BL/6J (56 days, male) 13.8
323186 Antisense, RP_040617_02_B10, Mouse strain C57BL/6J (56 days, male) 12.4

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