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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 158.5
Min nTPM: 34.7
Std nTPM: 24.8
Median nTPM:
137_1
83 years, male
158.5
308_1
70 years, female
150.3
501_1
88 years, male
145.1
4_1
88 years, female
138.1
490_1
67 years, female
137.9
313_1
79 years, female
135.6
491_1
89 years, female
135.1
413_1
59 years, female
112.5
117_1
61 years, male
109.8
142_1
61 years, female
107.9
145_1
84 years, male
105.5
414_1
84 years, female
102.6
314_1
67 years, male
102.0
264_1
73 years, female
98.7
315_1
62 years, female
98.7
120_1
70 years, female
97.8
119_1
70 years, female
95.8
162_1
79 years, female
91.7
288_1
66 years, female
90.6
406_1
79 years, male
90.2
324_1
76 years, male
90.1
351_1
91 years, male
89.3
126_1
63 years, male
88.5
506_1
65 years, male
87.6
17_1
71 years, male
85.8
415_1
77 years, female
85.5
526_1
61 years, male
85.5
375_1
74 years, female
85.1
254_1
77 years, female
84.4
89_1
63 years, male
84.2
295_1
61 years, female
84.0
394_1
75 years, female
82.9
452_1
88 years, female
82.6
389_1
86 years, female
82.2
503_1
68 years, male
81.8
109_1
81 years, female
81.0
173_1
67 years, male
81.0
32_1
67 years, male
80.6
43_1
64 years, female
79.2
518_1
75 years, female
79.2
6_1
73 years, female
78.9
379_1
60 years, male
78.7
41_1
94 years, female
78.6
293_1
68 years, female
78.3
18_1
88 years, male
77.8
466_1
57 years, female
76.6
307_1
66 years, female
75.2
350_1
84 years, female
74.1
348_1
84 years, male
73.5
149_1
88 years, male
73.4
447_1
81 years, male
73.3
115_1
83 years, male
73.0
495_1
57 years, female
72.9
499_1
55 years, female
71.5
480_1
63 years, male
69.4
9_1
66 years, female
68.8
42_1
85 years, male
68.7
354_1
81 years, female
68.2
139_1
64 years, female
68.0
349_1
83 years, male
68.0
468_1
89 years, male
67.4
396_1
62 years, male
66.8
81_1
67 years, male
66.6
317_1
60 years, male
66.1
265_1
87 years, male
65.8
243_1
75 years, male
65.5
376_1
75 years, female
65.4
266_1
85 years, male
64.7
189_1
76 years, male
62.8
291_1
76 years, male
62.2
319_1
81 years, male
61.0
320_1
89 years, female
60.8
172_1
72 years, female
60.7
177_1
74 years, male
60.5
237_1
82 years, male
58.9
356_1
87 years, female
58.5
404_1
82 years, female
58.0
311_1
78 years, male
57.6
384_1
83 years, male
56.7
153_1
70 years, female
56.3
517_1
88 years, male
55.9
321_1
62 years, female
55.8
316_1
62 years, male
55.7
386_1
76 years, male
55.7
35_1
74 years, female
55.4
246_1
77 years, male
54.6
251_1
78 years, male
53.8
322_1
76 years, male
53.3
217_1
76 years, male
53.1
335_1
73 years, female
52.9
347_1
72 years, male
52.8
286_1
68 years, female
52.6
318_1
68 years, male
52.2
353_1
82 years, female
51.6
99_1
64 years, male
51.5
377_1
82 years, female
50.5
425_1
59 years, female
48.0
163_1
78 years, male
46.2
405_1
91 years, male
45.7
292_1
71 years, male
45.1
2_1
77 years, female
43.4
229_1
69 years, female
42.6
352_1
62 years, male
39.1
355_1
70 years, female
36.4
218_1
71 years, female
34.7
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
