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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:142.3 nTPM
HPA:142.3 nTPM
GTEx:189.0 nTPM
FANTOM5:345.3 Scaled Tags Per Million
Pig:166.0 nTPM
Mouse:126.5 nTPM
Allen mouse:7.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 142.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 129.1
2411 Female, age 72, unknown 149.4
1870 Female, age 42, unknown 143.5
2019 Male, age 18, unknown 137.3
2219 Male, age 76, both hemispheres 133.8
1833 Male, age 53, unknown 131.1
1830 Male, age 51, unknown 128.0
1827 Male, age 72, unknown 123.6
2828 Female, age 72, unknown 121.2
2666 Male, age 74, left hemisphere 116.8
2586 Male, age 75, left hemisphere 106.6
Dorsal raphe nucleus
nTPM: 135.8
2750 Male, age 76, both hemispheres 144.9
2298 Female, age 72, unknown 140.2
1828 Male, age 53, unknown 135.3
2047 Male, age 72, unknown 133.5
2016 Female, age 72, unknown 124.9
Inferior colliculus
nTPM: 129.3
2097 Female, age 72, unknown 134.8
1848 Female, age 42, unknown 131.3
1890 Male, age 53, unknown 128.9
2849 Male, age 72, unknown 122.2
Median raphe nucleus
nTPM: 137.7
2220 Male, age 76, midline 137.7
Pedunculopontine tegmental nucleus
nTPM: 142.3
2334 Male, age 80, both hemispheres 150.1
1921 Female, age 85, both hemispheres 140.6
2338 Male, age 61, both hemispheres 136.1
Periaquaductal grey, anterior
nTPM: 127.3
1947 Male, age 18, unknown 133.0
2502 Female, age 75, unknown 129.2
1795 Male, age 51, unknown 119.7
Periaquaductal grey, dorsal
nTPM: 121.5
2464 Female, age 72, unknown 125.0
1840 Male, age 53, unknown 123.0
2850 Male, age 76, both hemispheres 122.2
1831 Male, age 72, unknown 115.8
Periaquaductal grey, lateral
nTPM: 120.1
2272 Male, age 74, both hemispheres 127.2
2053 Male, age 18, unknown 117.9
2140 Male, age 76, both hemispheres 115.2
Pretectal area
nTPM: 129.3
2667 Female, age 75, unknown 151.9
1817 Female, age 42, unknown 136.3
2007 Male, age 72, unknown 134.3
2224 Female, age 72, unknown 132.7
2273 Male, age 74, both hemispheres 129.5
1944 Female, age 72, unknown 127.7
2316 Male, age 76, right hemisphere 126.9
1816 Male, age 51, unknown 125.4
1815 Male, age 53, unknown 124.6
2825 Male, age 18, unknown 120.4
2407 Male, age 75, both hemispheres 112.9
Red nucleus
nTPM: 136.0
1821 Female, age 72, unknown 164.7
1954 Female, age 42, unknown 150.1
1865 Male, age 51, unknown 141.7
1904 Male, age 53, unknown 139.5
2227 Male, age 72, unknown 138.2
2769 Male, age 72, unknown 137.1
2785 Male, age 18, unknown 136.4
2823 Male, age 76, right hemisphere 135.3
2503 Female, age 72, unknown 133.7
2725 Female, age 75, unknown 122.7
2588 Male, age 74, left hemisphere 121.9
2584 Male, age 75, left hemisphere 110.3
Substantia nigra
nTPM: 137.5
2241 Male, age 72, unknown 160.1
1916 Female, age 42, unknown 157.4
1851 Male, age 51, unknown 145.2
2409 Female, age 72, unknown 142.8
1941 Male, age 53, unknown 141.0
1889 Female, age 72, unknown 140.4
2699 Male, age 18, unknown 132.0
2590 Female, age 75, unknown 123.3
2665 Male, age 74, both hemispheres 117.8
2583 Male, age 75, right hemisphere 115.0
Superior colliculus
nTPM: 123.1
2587 Male, age 74, left hemisphere 135.9
1895 Male, age 76, right hemisphere 134.2
1839 Male, age 51, unknown 125.6
1913 Female, age 42, unknown 124.7
2668 Female, age 75, unknown 124.0
2087 Female, age 72, unknown 122.5
1796 Male, age 53, unknown 122.4
2261 Male, age 18, unknown 119.5
1995 Male, age 72, unknown 115.2
2664 Male, age 75, both hemispheres 106.8
Ventral tegmental area
nTPM: 139.8
2410 Female, age 72, unknown 152.0
1915 Female, age 42, unknown 146.5
2218 Male, age 76, both hemispheres 145.9
2223 Female, age 72, unknown 137.9
1942 Male, age 51, unknown 130.4
2021 Male, age 53, unknown 126.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 189.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 189.0
Samples: 139

Max nTPM: 465.5
Min nTPM: 100.4
Std nTPM: 55.8
Median nTPM: 179.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 465.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 419.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 346.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 315.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 306.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 297.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 296.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 285.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 276.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 267.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 255.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 254.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 253.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 252.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 252.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 249.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 246.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 243.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 241.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 241.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 238.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 237.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 234.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 232.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 231.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 231.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 230.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 230.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 225.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 224.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 223.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 220.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 218.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 217.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 212.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 211.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 210.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 209.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 208.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 206.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 206.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 204.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 204.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 204.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 201.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 200.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 198.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 196.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 195.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 195.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 194.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 193.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 193.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 192.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 191.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 191.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 191.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 191.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 189.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 189.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 187.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 187.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 186.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 185.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 183.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 183.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 183.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 181.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 179.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 179.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 179.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 178.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 177.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 176.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 175.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 174.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 174.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 173.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 173.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 171.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 169.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 167.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 167.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 167.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 166.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 165.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 165.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 164.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 162.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 161.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 161.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 161.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 160.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 160.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 160.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 160.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 159.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 159.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 158.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 158.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 157.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 157.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 157.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 156.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 156.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 155.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 154.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 153.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 153.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 152.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 151.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 149.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 148.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 147.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 147.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 144.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 144.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 143.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 142.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 142.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 140.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 134.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 132.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 132.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 131.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 129.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 127.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 126.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 123.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 117.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 115.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 113.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 108.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 108.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 108.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 107.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 105.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 100.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 100.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 345.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 345.3
FF:10158-103A5 76 years, female 345.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 166.0
Pig sample Sample description nTPM
Midbrain
nTPM: 166.0
Samples: 4

Max nTPM: 289.0
Min nTPM: 99.6
Sample A Female 289.0
Sample B Female 148.8
Sample C Male 99.6
Sample D Male 126.4
Periaqueductal gray
nTPM: 107.3
Samples: 3

Max nTPM: 127.8
Min nTPM: 95.3
Sample B Female 127.8
Sample C Male 98.7
Sample D Male 95.3
Substantia nigra
nTPM: 131.4
Samples: 4

Max nTPM: 201.9
Min nTPM: 91.1
Sample A Female 201.9
Sample B Female 91.1
Sample C Male 108.3
Sample D Male 124.1
Superior colliculi
nTPM: 148.3
Samples: 4

Max nTPM: 209.3
Min nTPM: 101.0
Sample A Female 209.3
Sample B Female 101.0
Sample C Male 136.0
Sample D Male 146.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 126.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 126.5
Samples: 4

Max nTPM: 130.2
Min nTPM: 123.2
Sample A Male 125.3
Sample B Male 127.3
Sample C Female 123.2
Sample D Female 130.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 7.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 7.2
74635292 Antisense, RP_060215_03_F04, Mouse strain C57BL/6J (56 days, male) 7.2

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