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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:156.3 nTPM
HPA:156.3 nTPM
GTEx:167.7 nTPM
FANTOM5:148.1 Scaled Tags Per Million
Pig:70.8 nTPM
Mouse:73.9 nTPM
Allen mouse:2.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 156.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 148.5
1870 Female, age 42, unknown 153.5
2411 Female, age 72, unknown 153.4
2586 Male, age 75, left hemisphere 152.9
2828 Female, age 72, unknown 151.9
1833 Male, age 53, unknown 148.0
2019 Male, age 18, unknown 147.6
1827 Male, age 72, unknown 146.6
1830 Male, age 51, unknown 146.1
2219 Male, age 76, both hemispheres 143.1
2666 Male, age 74, left hemisphere 141.9
Dorsal raphe nucleus
nTPM: 153.3
2298 Female, age 72, unknown 163.3
2750 Male, age 76, both hemispheres 151.8
2016 Female, age 72, unknown 150.9
1828 Male, age 53, unknown 150.5
2047 Male, age 72, unknown 149.8
Inferior colliculus
nTPM: 146.2
2097 Female, age 72, unknown 152.2
1890 Male, age 53, unknown 145.9
1848 Female, age 42, unknown 143.5
2849 Male, age 72, unknown 143.2
Median raphe nucleus
nTPM: 150.4
2220 Male, age 76, midline 150.4
Pedunculopontine tegmental nucleus
nTPM: 152.3
2338 Male, age 61, both hemispheres 158.5
2334 Male, age 80, both hemispheres 152.8
1921 Female, age 85, both hemispheres 145.7
Periaquaductal grey, anterior
nTPM: 156.3
1947 Male, age 18, unknown 159.6
1795 Male, age 51, unknown 155.5
2502 Female, age 75, unknown 153.8
Periaquaductal grey, dorsal
nTPM: 147.8
1840 Male, age 53, unknown 151.7
2850 Male, age 76, both hemispheres 147.9
1831 Male, age 72, unknown 146.2
2464 Female, age 72, unknown 145.2
Periaquaductal grey, lateral
nTPM: 150.7
2272 Male, age 74, both hemispheres 156.5
2053 Male, age 18, unknown 149.1
2140 Male, age 76, both hemispheres 146.3
Pretectal area
nTPM: 151.1
2273 Male, age 74, both hemispheres 161.4
2224 Female, age 72, unknown 157.0
1817 Female, age 42, unknown 153.1
2667 Female, age 75, unknown 151.8
2007 Male, age 72, unknown 151.3
1815 Male, age 53, unknown 150.9
2825 Male, age 18, unknown 149.5
1816 Male, age 51, unknown 148.8
2407 Male, age 75, both hemispheres 148.3
1944 Female, age 72, unknown 146.4
2316 Male, age 76, right hemisphere 143.5
Red nucleus
nTPM: 149.3
2503 Female, age 72, unknown 153.7
1865 Male, age 51, unknown 153.1
2725 Female, age 75, unknown 152.8
2769 Male, age 72, unknown 151.4
2227 Male, age 72, unknown 151.3
1821 Female, age 72, unknown 150.7
1904 Male, age 53, unknown 150.5
1954 Female, age 42, unknown 149.5
2785 Male, age 18, unknown 148.2
2823 Male, age 76, right hemisphere 146.0
2584 Male, age 75, left hemisphere 145.0
2588 Male, age 74, left hemisphere 139.9
Substantia nigra
nTPM: 150.0
1916 Female, age 42, unknown 158.8
1851 Male, age 51, unknown 156.9
2409 Female, age 72, unknown 153.0
2241 Male, age 72, unknown 150.7
2583 Male, age 75, right hemisphere 148.3
2699 Male, age 18, unknown 148.2
1889 Female, age 72, unknown 148.0
2590 Female, age 75, unknown 147.3
2665 Male, age 74, both hemispheres 146.0
1941 Male, age 53, unknown 143.0
Superior colliculus
nTPM: 149.2
2587 Male, age 74, left hemisphere 154.5
1995 Male, age 72, unknown 152.9
1913 Female, age 42, unknown 152.7
1796 Male, age 53, unknown 152.0
2261 Male, age 18, unknown 152.0
2668 Female, age 75, unknown 149.1
2087 Female, age 72, unknown 147.3
2664 Male, age 75, both hemispheres 146.2
1839 Male, age 51, unknown 143.2
1895 Male, age 76, right hemisphere 142.2
Ventral tegmental area
nTPM: 153.3
1915 Female, age 42, unknown 155.6
2021 Male, age 53, unknown 155.1
2410 Female, age 72, unknown 155.0
1942 Male, age 51, unknown 154.2
2223 Female, age 72, unknown 150.7
2218 Male, age 76, both hemispheres 149.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 167.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 167.7
Samples: 139

Max nTPM: 403.5
Min nTPM: 80.6
Std nTPM: 52.4
Median nTPM: 152.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 403.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 382.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 305.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 290.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 284.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 280.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 270.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 262.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 258.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 257.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 253.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 249.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 246.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 241.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 240.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 234.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 229.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 224.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 222.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 222.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 222.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 219.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 218.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 209.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 207.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 205.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 204.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 201.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 201.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 198.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 195.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 193.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 192.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 189.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 188.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 186.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 185.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 185.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 179.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 179.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 177.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 175.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 174.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 174.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 174.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 174.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 173.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 172.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 172.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 171.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 170.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 170.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 167.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 166.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 166.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 166.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 165.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 163.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 163.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 162.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 160.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 160.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 160.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 160.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 156.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 155.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 155.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 154.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 152.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 152.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 152.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 152.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 152.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 151.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 151.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 150.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 149.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 149.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 149.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 147.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 146.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 146.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 145.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 145.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 144.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 144.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 142.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 142.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 142.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 140.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 140.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 140.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 140.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 139.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 139.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 139.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 137.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 137.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 136.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 136.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 135.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 133.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 133.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 133.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 132.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 132.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 132.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 131.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 131.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 131.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 131.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 131.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 130.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 130.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 128.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 128.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 126.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 124.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 124.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 123.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 121.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 120.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 119.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 119.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 118.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 118.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 117.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 116.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 116.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 115.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 114.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 111.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 110.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 105.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 104.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 99.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 87.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 82.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 80.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 148.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 148.1
FF:10158-103A5 76 years, female 148.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 70.8
Pig sample Sample description nTPM
Midbrain
nTPM: 67.2
Samples: 4

Max nTPM: 110.7
Min nTPM: 38.4
Sample A Female 110.7
Sample B Female 64.5
Sample C Male 55.1
Sample D Male 38.4
Periaqueductal gray
nTPM: 46.7
Samples: 3

Max nTPM: 49.6
Min nTPM: 44.1
Sample B Female 46.3
Sample C Male 49.6
Sample D Male 44.1
Substantia nigra
nTPM: 70.8
Samples: 4

Max nTPM: 94.3
Min nTPM: 56.0
Sample A Female 94.3
Sample B Female 73.1
Sample C Male 59.6
Sample D Male 56.0
Superior colliculi
nTPM: 68.3
Samples: 4

Max nTPM: 85.9
Min nTPM: 50.3
Sample A Female 81.0
Sample B Female 85.9
Sample C Male 55.8
Sample D Male 50.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 73.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 73.9
Samples: 4

Max nTPM: 79.3
Min nTPM: 69.1
Sample A Male 76.3
Sample B Male 70.7
Sample C Female 69.1
Sample D Female 79.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 2.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.6
69885768 Antisense, RP_050512_03_D07, Mouse strain C57BL/6J (56 days, male) 2.6

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