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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:79.8 nTPM
HPA:79.8 nTPM
GTEx:63.0 nTPM
FANTOM5:116.0 Scaled Tags Per Million
Pig:93.3 nTPM
Mouse:241.3 nTPM
Allen mouse:13.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 79.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 65.5
2019 Male, age 18, unknown 73.6
1827 Male, age 72, unknown 72.1
2411 Female, age 72, unknown 72.1
2828 Female, age 72, unknown 70.0
1833 Male, age 53, unknown 69.1
1870 Female, age 42, unknown 67.2
2219 Male, age 76, both hemispheres 66.2
1830 Male, age 51, unknown 64.4
2666 Male, age 74, left hemisphere 54.2
2586 Male, age 75, left hemisphere 46.4
Dorsal raphe nucleus
nTPM: 72.0
2298 Female, age 72, unknown 98.5
2750 Male, age 76, both hemispheres 68.2
1828 Male, age 53, unknown 66.6
2047 Male, age 72, unknown 66.3
2016 Female, age 72, unknown 60.3
Inferior colliculus
nTPM: 72.0
2097 Female, age 72, unknown 79.5
1848 Female, age 42, unknown 73.0
2849 Male, age 72, unknown 67.8
1890 Male, age 53, unknown 67.6
Median raphe nucleus
nTPM: 71.5
2220 Male, age 76, midline 71.5
Pedunculopontine tegmental nucleus
nTPM: 73.8
2334 Male, age 80, both hemispheres 75.6
2338 Male, age 61, both hemispheres 74.2
1921 Female, age 85, both hemispheres 71.7
Periaquaductal grey, anterior
nTPM: 66.5
1947 Male, age 18, unknown 67.0
1795 Male, age 51, unknown 66.8
2502 Female, age 75, unknown 65.8
Periaquaductal grey, dorsal
nTPM: 67.8
2850 Male, age 76, both hemispheres 73.1
1840 Male, age 53, unknown 68.4
1831 Male, age 72, unknown 65.6
2464 Female, age 72, unknown 64.2
Periaquaductal grey, lateral
nTPM: 75.6
2272 Male, age 74, both hemispheres 97.3
2140 Male, age 76, both hemispheres 65.5
2053 Male, age 18, unknown 64.1
Pretectal area
nTPM: 79.8
2273 Male, age 74, both hemispheres 99.3
1944 Female, age 72, unknown 86.8
2007 Male, age 72, unknown 85.5
1817 Female, age 42, unknown 85.2
1816 Male, age 51, unknown 83.5
2667 Female, age 75, unknown 79.9
2224 Female, age 72, unknown 79.7
1815 Male, age 53, unknown 78.7
2407 Male, age 75, both hemispheres 73.9
2825 Male, age 18, unknown 64.3
2316 Male, age 76, right hemisphere 60.7
Red nucleus
nTPM: 64.6
2785 Male, age 18, unknown 72.7
2725 Female, age 75, unknown 71.4
1821 Female, age 72, unknown 69.5
2823 Male, age 76, right hemisphere 68.6
2769 Male, age 72, unknown 66.1
2503 Female, age 72, unknown 64.6
1954 Female, age 42, unknown 63.1
1865 Male, age 51, unknown 63.0
2227 Male, age 72, unknown 61.5
1904 Male, age 53, unknown 59.7
2584 Male, age 75, left hemisphere 58.8
2588 Male, age 74, left hemisphere 56.2
Substantia nigra
nTPM: 68.4
1889 Female, age 72, unknown 81.1
2409 Female, age 72, unknown 76.6
1941 Male, age 53, unknown 74.4
1916 Female, age 42, unknown 73.4
2241 Male, age 72, unknown 68.3
1851 Male, age 51, unknown 68.0
2699 Male, age 18, unknown 66.0
2590 Female, age 75, unknown 65.5
2665 Male, age 74, both hemispheres 56.9
2583 Male, age 75, right hemisphere 53.8
Superior colliculus
nTPM: 66.8
2087 Female, age 72, unknown 85.9
1895 Male, age 76, right hemisphere 74.1
1796 Male, age 53, unknown 71.1
2261 Male, age 18, unknown 70.6
2587 Male, age 74, left hemisphere 67.9
1839 Male, age 51, unknown 66.4
1913 Female, age 42, unknown 63.8
1995 Male, age 72, unknown 62.4
2668 Female, age 75, unknown 60.5
2664 Male, age 75, both hemispheres 45.6
Ventral tegmental area
nTPM: 70.2
2410 Female, age 72, unknown 85.4
2218 Male, age 76, both hemispheres 76.7
1915 Female, age 42, unknown 69.7
1942 Male, age 51, unknown 64.6
2021 Male, age 53, unknown 63.9
2223 Female, age 72, unknown 61.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 63.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 63.0
Samples: 139

Max nTPM: 107.7
Min nTPM: 37.8
Std nTPM: 13.7
Median nTPM: 61.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 107.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 106.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 106.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 95.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 91.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 91.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 89.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 88.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 85.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 85.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 85.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 83.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 83.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 83.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 82.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 82.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 81.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 80.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 79.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 76.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 75.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 73.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 72.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 72.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 72.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 72.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 71.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 71.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 71.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 70.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 70.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 70.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 70.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 69.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 69.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 69.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 69.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 69.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 68.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 68.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 68.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 68.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 68.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 68.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 68.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 67.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 67.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 67.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 67.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 66.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 66.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 66.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 66.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 66.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 65.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 65.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 65.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 65.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 64.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 64.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 64.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 63.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 63.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 62.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 62.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 62.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 62.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 62.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 61.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 61.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 61.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 61.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 61.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 60.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 60.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 60.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 60.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 59.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 59.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 59.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 58.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 58.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 58.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 57.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 57.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 57.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 56.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 56.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 56.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 56.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 56.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 55.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 55.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 55.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 55.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 55.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 54.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 54.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 54.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 54.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 54.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 54.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 54.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 53.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 53.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 53.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 53.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 52.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 51.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 51.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 51.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 51.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 51.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 50.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 50.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 50.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 50.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 49.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 49.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 48.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 48.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 48.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 48.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 48.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 47.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 47.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 46.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 46.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 46.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 46.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 45.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 45.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 44.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 41.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 41.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 40.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 39.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 38.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 37.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 116.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 116.0
FF:10158-103A5 76 years, female 116.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 93.3
Pig sample Sample description nTPM
Midbrain
nTPM: 86.9
Samples: 4

Max nTPM: 110.5
Min nTPM: 72.4
Sample A Female 81.8
Sample B Female 72.4
Sample C Male 110.5
Sample D Male 82.8
Periaqueductal gray
nTPM: 57.6
Samples: 3

Max nTPM: 62.1
Min nTPM: 51.7
Sample B Female 58.9
Sample C Male 62.1
Sample D Male 51.7
Substantia nigra
nTPM: 81.8
Samples: 4

Max nTPM: 108.9
Min nTPM: 56.6
Sample A Female 108.9
Sample B Female 68.1
Sample C Male 93.4
Sample D Male 56.6
Superior colliculi
nTPM: 93.3
Samples: 4

Max nTPM: 107.8
Min nTPM: 73.1
Sample A Female 101.2
Sample B Female 91.2
Sample C Male 107.8
Sample D Male 73.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 241.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 241.3
Samples: 4

Max nTPM: 246.4
Min nTPM: 233.4
Sample A Male 239.4
Sample B Male 246.4
Sample C Female 245.8
Sample D Female 233.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 13.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 13.9
69015578 Antisense, RP_050315_01_C06, Mouse strain C57BL/6J (56 days, male) 13.9

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