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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:152.9 nTPM
HPA:152.9 nTPM
GTEx:130.4 nTPM
FANTOM5:292.0 Scaled Tags Per Million
Pig:71.6 nTPM
Mouse:61.8 nTPM
Allen mouse:2.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 152.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 145.8
2828 Female, age 72, unknown 163.2
1870 Female, age 42, unknown 159.6
1830 Male, age 51, unknown 149.9
2586 Male, age 75, left hemisphere 149.0
2411 Female, age 72, unknown 147.8
1833 Male, age 53, unknown 146.6
2666 Male, age 74, left hemisphere 142.2
1827 Male, age 72, unknown 139.7
2019 Male, age 18, unknown 138.8
2219 Male, age 76, both hemispheres 121.4
Dorsal raphe nucleus
nTPM: 151.0
2016 Female, age 72, unknown 163.5
1828 Male, age 53, unknown 152.7
2047 Male, age 72, unknown 149.7
2298 Female, age 72, unknown 147.7
2750 Male, age 76, both hemispheres 141.6
Inferior colliculus
nTPM: 143.4
1848 Female, age 42, unknown 147.1
1890 Male, age 53, unknown 142.9
2849 Male, age 72, unknown 142.9
2097 Female, age 72, unknown 140.6
Median raphe nucleus
nTPM: 137.6
2220 Male, age 76, midline 137.6
Pedunculopontine tegmental nucleus
nTPM: 144.9
2338 Male, age 61, both hemispheres 158.9
2334 Male, age 80, both hemispheres 142.1
1921 Female, age 85, both hemispheres 133.8
Periaquaductal grey, anterior
nTPM: 144.0
2502 Female, age 75, unknown 146.1
1795 Male, age 51, unknown 145.7
1947 Male, age 18, unknown 140.2
Periaquaductal grey, dorsal
nTPM: 150.2
1831 Male, age 72, unknown 154.4
2850 Male, age 76, both hemispheres 151.0
1840 Male, age 53, unknown 149.5
2464 Female, age 72, unknown 145.9
Periaquaductal grey, lateral
nTPM: 152.2
2140 Male, age 76, both hemispheres 157.7
2053 Male, age 18, unknown 155.2
2272 Male, age 74, both hemispheres 143.8
Pretectal area
nTPM: 141.8
2316 Male, age 76, right hemisphere 151.9
2273 Male, age 74, both hemispheres 151.4
2825 Male, age 18, unknown 150.6
2224 Female, age 72, unknown 145.3
2667 Female, age 75, unknown 144.0
1815 Male, age 53, unknown 141.7
1817 Female, age 42, unknown 140.4
1944 Female, age 72, unknown 138.1
2407 Male, age 75, both hemispheres 136.9
1816 Male, age 51, unknown 131.9
2007 Male, age 72, unknown 128.1
Red nucleus
nTPM: 152.9
1904 Male, age 53, unknown 162.9
1954 Female, age 42, unknown 162.8
1821 Female, age 72, unknown 162.3
2227 Male, age 72, unknown 159.8
2769 Male, age 72, unknown 157.0
2503 Female, age 72, unknown 155.8
1865 Male, age 51, unknown 154.5
2725 Female, age 75, unknown 151.0
2823 Male, age 76, right hemisphere 150.9
2588 Male, age 74, left hemisphere 145.5
2785 Male, age 18, unknown 139.1
2584 Male, age 75, left hemisphere 132.8
Substantia nigra
nTPM: 150.5
2699 Male, age 18, unknown 176.9
1851 Male, age 51, unknown 154.1
1916 Female, age 42, unknown 153.6
2590 Female, age 75, unknown 153.5
2409 Female, age 72, unknown 153.1
2665 Male, age 74, both hemispheres 152.8
2583 Male, age 75, right hemisphere 145.0
1889 Female, age 72, unknown 139.7
2241 Male, age 72, unknown 138.3
1941 Male, age 53, unknown 137.6
Superior colliculus
nTPM: 146.3
1995 Male, age 72, unknown 168.8
1913 Female, age 42, unknown 163.8
2587 Male, age 74, left hemisphere 147.2
2087 Female, age 72, unknown 146.3
1796 Male, age 53, unknown 144.1
1839 Male, age 51, unknown 144.1
2664 Male, age 75, both hemispheres 141.8
2668 Female, age 75, unknown 138.5
2261 Male, age 18, unknown 136.1
1895 Male, age 76, right hemisphere 132.6
Ventral tegmental area
nTPM: 151.4
1915 Female, age 42, unknown 153.7
2021 Male, age 53, unknown 153.4
2410 Female, age 72, unknown 152.6
2223 Female, age 72, unknown 151.4
1942 Male, age 51, unknown 150.9
2218 Male, age 76, both hemispheres 146.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 130.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 130.4
Samples: 139

Max nTPM: 335.0
Min nTPM: 25.6
Std nTPM: 50.5
Median nTPM: 120.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 335.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 306.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 273.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 269.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 262.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 252.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 235.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 226.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 224.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 212.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 208.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 204.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 203.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 201.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 193.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 190.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 188.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 184.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 183.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 181.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 176.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 176.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 175.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 173.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 168.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 167.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 167.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 166.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 165.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 165.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 165.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 159.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 158.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 157.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 156.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 155.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 153.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 145.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 144.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 141.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 138.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 137.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 136.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 136.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 135.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 132.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 131.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 131.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 131.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 131.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 130.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 129.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 128.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 127.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 126.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 125.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 125.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 125.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 124.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 123.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 122.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 122.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 121.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 121.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 121.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 121.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 121.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 120.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 120.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 120.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 117.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 117.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 116.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 116.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 115.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 114.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 114.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 114.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 113.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 110.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 110.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 110.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 109.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 108.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 106.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 106.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 106.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 106.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 105.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 105.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 105.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 105.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 105.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 103.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 103.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 103.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 101.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 101.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 101.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 101.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 100.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 99.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 99.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 98.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 97.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 97.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 97.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 96.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 96.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 96.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 96.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 96.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 96.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 95.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 94.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 93.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 92.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 89.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 88.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 86.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 85.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 84.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 84.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 84.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 84.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 84.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 83.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 83.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 80.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 79.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 76.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 76.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 74.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 66.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 57.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 56.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 51.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 44.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 25.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 292.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 292.0
FF:10158-103A5 76 years, female 292.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 71.6
Pig sample Sample description nTPM
Midbrain
nTPM: 63.3
Samples: 4

Max nTPM: 101.9
Min nTPM: 39.1
Sample A Female 101.9
Sample B Female 58.4
Sample C Male 53.7
Sample D Male 39.1
Periaqueductal gray
nTPM: 51.0
Samples: 3

Max nTPM: 55.2
Min nTPM: 43.6
Sample B Female 54.2
Sample C Male 55.2
Sample D Male 43.6
Substantia nigra
nTPM: 65.9
Samples: 4

Max nTPM: 75.0
Min nTPM: 55.6
Sample A Female 66.1
Sample B Female 75.0
Sample C Male 55.6
Sample D Male 66.7
Superior colliculi
nTPM: 71.6
Samples: 4

Max nTPM: 101.6
Min nTPM: 55.8
Sample A Female 73.1
Sample B Female 101.6
Sample C Male 55.9
Sample D Male 55.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 61.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 61.8
Samples: 4

Max nTPM: 65.3
Min nTPM: 57.9
Sample A Male 65.3
Sample B Male 57.9
Sample C Female 61.9
Sample D Female 61.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 2.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.0
1956 Antisense, RP_Baylor_253962, Mouse strain C57BL/6J (56 days, male) 2.0
1957 Antisense, RP_Baylor_253962, Mouse strain C57BL/6J (56 days, male) 1.5

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