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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:187.5 nTPM
HPA:187.5 nTPM
GTEx:161.1 nTPM
FANTOM5:40.3 Scaled Tags Per Million
Pig:186.9 nTPM
Mouse:158.1 nTPM
Allen mouse:4.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 187.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 176.9
2666 Male, age 74, left hemisphere 203.0
1827 Male, age 72, unknown 182.3
2411 Female, age 72, unknown 182.1
2019 Male, age 18, unknown 178.5
2828 Female, age 72, unknown 174.3
1833 Male, age 53, unknown 173.4
2586 Male, age 75, left hemisphere 171.3
1870 Female, age 42, unknown 170.8
1830 Male, age 51, unknown 168.8
2219 Male, age 76, both hemispheres 164.4
Dorsal raphe nucleus
nTPM: 182.8
2298 Female, age 72, unknown 196.3
2047 Male, age 72, unknown 188.4
2750 Male, age 76, both hemispheres 179.9
1828 Male, age 53, unknown 179.0
2016 Female, age 72, unknown 170.1
Inferior colliculus
nTPM: 165.0
1848 Female, age 42, unknown 167.3
2849 Male, age 72, unknown 166.9
2097 Female, age 72, unknown 165.4
1890 Male, age 53, unknown 160.5
Median raphe nucleus
nTPM: 187.5
2220 Male, age 76, midline 187.5
Pedunculopontine tegmental nucleus
nTPM: 176.7
2334 Male, age 80, both hemispheres 186.6
2338 Male, age 61, both hemispheres 173.4
1921 Female, age 85, both hemispheres 170.0
Periaquaductal grey, anterior
nTPM: 173.1
1795 Male, age 51, unknown 180.2
1947 Male, age 18, unknown 174.9
2502 Female, age 75, unknown 164.2
Periaquaductal grey, dorsal
nTPM: 166.0
1840 Male, age 53, unknown 167.6
2850 Male, age 76, both hemispheres 166.5
2464 Female, age 72, unknown 165.1
1831 Male, age 72, unknown 164.9
Periaquaductal grey, lateral
nTPM: 164.4
2272 Male, age 74, both hemispheres 169.2
2053 Male, age 18, unknown 165.0
2140 Male, age 76, both hemispheres 159.1
Pretectal area
nTPM: 175.8
2007 Male, age 72, unknown 190.6
1817 Female, age 42, unknown 190.3
1816 Male, age 51, unknown 184.4
1815 Male, age 53, unknown 183.1
1944 Female, age 72, unknown 182.3
2224 Female, age 72, unknown 173.4
2667 Female, age 75, unknown 170.0
2825 Male, age 18, unknown 169.7
2273 Male, age 74, both hemispheres 166.7
2407 Male, age 75, both hemispheres 165.9
2316 Male, age 76, right hemisphere 157.0
Red nucleus
nTPM: 167.3
1821 Female, age 72, unknown 180.3
2725 Female, age 75, unknown 174.4
2785 Male, age 18, unknown 170.9
2588 Male, age 74, left hemisphere 168.6
2584 Male, age 75, left hemisphere 168.4
2503 Female, age 72, unknown 167.9
1954 Female, age 42, unknown 166.8
2769 Male, age 72, unknown 164.1
2227 Male, age 72, unknown 163.7
2823 Male, age 76, right hemisphere 161.9
1904 Male, age 53, unknown 161.3
1865 Male, age 51, unknown 159.4
Substantia nigra
nTPM: 186.0
1916 Female, age 42, unknown 207.3
1941 Male, age 53, unknown 198.7
1851 Male, age 51, unknown 197.4
1889 Female, age 72, unknown 186.5
2665 Male, age 74, both hemispheres 186.3
2241 Male, age 72, unknown 181.3
2699 Male, age 18, unknown 180.0
2409 Female, age 72, unknown 175.1
2590 Female, age 75, unknown 174.4
2583 Male, age 75, right hemisphere 172.9
Superior colliculus
nTPM: 169.8
2668 Female, age 75, unknown 186.4
2087 Female, age 72, unknown 177.7
1796 Male, age 53, unknown 175.2
2587 Male, age 74, left hemisphere 173.0
2261 Male, age 18, unknown 169.3
1839 Male, age 51, unknown 168.3
1895 Male, age 76, right hemisphere 164.7
2664 Male, age 75, both hemispheres 163.7
1913 Female, age 42, unknown 162.3
1995 Male, age 72, unknown 157.1
Ventral tegmental area
nTPM: 178.8
1915 Female, age 42, unknown 191.8
2410 Female, age 72, unknown 191.5
2218 Male, age 76, both hemispheres 178.9
1942 Male, age 51, unknown 170.6
2223 Female, age 72, unknown 170.2
2021 Male, age 53, unknown 170.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 161.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 161.1
Samples: 139

Max nTPM: 321.9
Min nTPM: 96.8
Std nTPM: 37.8
Median nTPM: 153.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 321.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 261.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 244.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 243.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 238.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 237.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 237.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 226.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 224.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 222.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 220.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 219.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 218.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 217.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 215.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 212.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 211.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 210.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 208.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 208.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 204.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 203.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 202.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 197.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 194.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 191.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 190.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 189.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 188.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 187.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 184.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 183.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 182.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 179.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 178.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 178.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 177.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 177.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 176.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 175.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 175.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 173.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 173.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 172.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 171.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 171.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 171.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 171.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 171.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 171.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 170.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 170.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 168.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 167.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 167.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 166.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 166.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 165.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 164.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 164.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 163.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 162.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 161.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 157.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 157.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 156.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 156.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 155.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 153.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 153.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 152.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 152.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 150.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 149.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 148.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 148.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 147.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 146.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 145.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 145.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 144.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 144.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 143.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 143.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 143.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 142.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 142.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 142.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 142.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 142.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 141.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 140.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 139.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 139.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 139.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 138.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 138.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 137.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 137.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 136.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 136.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 136.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 136.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 135.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 135.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 134.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 134.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 133.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 133.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 133.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 132.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 131.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 131.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 129.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 128.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 128.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 126.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 126.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 126.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 125.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 124.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 123.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 123.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 122.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 121.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 119.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 117.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 116.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 116.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 116.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 112.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 108.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 105.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 103.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 101.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 101.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 100.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 98.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 96.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 40.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 40.3
FF:10158-103A5 76 years, female 40.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 186.9
Pig sample Sample description nTPM
Midbrain
nTPM: 174.1
Samples: 4

Max nTPM: 228.5
Min nTPM: 146.6
Sample A Female 228.5
Sample B Female 159.7
Sample C Male 161.6
Sample D Male 146.6
Periaqueductal gray
nTPM: 145.5
Samples: 3

Max nTPM: 161.3
Min nTPM: 133.1
Sample B Female 142.2
Sample C Male 161.3
Sample D Male 133.1
Substantia nigra
nTPM: 169.3
Samples: 4

Max nTPM: 220.4
Min nTPM: 139.6
Sample A Female 220.4
Sample B Female 149.3
Sample C Male 168.0
Sample D Male 139.6
Superior colliculi
nTPM: 186.9
Samples: 4

Max nTPM: 225.4
Min nTPM: 164.5
Sample A Female 225.4
Sample B Female 186.0
Sample C Male 171.7
Sample D Male 164.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 158.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 158.2
Samples: 4

Max nTPM: 165.1
Min nTPM: 153.4
Sample A Male 155.2
Sample B Male 153.4
Sample C Female 158.9
Sample D Female 165.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 4.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.9
79544798 Antisense, RP_071018_01_C08, Mouse strain C57BL/6J (56 days, male) 4.9

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