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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:239.0 nTPM
HPA:239.0 nTPM
GTEx:326.4 nTPM
FANTOM5:373.9 Scaled Tags Per Million
Pig:176.7 nTPM
Mouse:202.1 nTPM
Allen mouse:0.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 239.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 220.9
2666 Male, age 74, left hemisphere 252.7
2586 Male, age 75, left hemisphere 228.2
2411 Female, age 72, unknown 224.8
1827 Male, age 72, unknown 222.9
1833 Male, age 53, unknown 222.7
1830 Male, age 51, unknown 221.1
1870 Female, age 42, unknown 219.5
2828 Female, age 72, unknown 214.4
2019 Male, age 18, unknown 210.2
2219 Male, age 76, both hemispheres 192.5
Dorsal raphe nucleus
nTPM: 211.1
2016 Female, age 72, unknown 227.9
1828 Male, age 53, unknown 220.5
2750 Male, age 76, both hemispheres 207.7
2047 Male, age 72, unknown 206.7
2298 Female, age 72, unknown 192.5
Inferior colliculus
nTPM: 203.4
1890 Male, age 53, unknown 209.5
1848 Female, age 42, unknown 208.7
2849 Male, age 72, unknown 199.7
2097 Female, age 72, unknown 195.7
Median raphe nucleus
nTPM: 200.8
2220 Male, age 76, midline 200.8
Pedunculopontine tegmental nucleus
nTPM: 209.0
2334 Male, age 80, both hemispheres 218.1
2338 Male, age 61, both hemispheres 210.1
1921 Female, age 85, both hemispheres 199.0
Periaquaductal grey, anterior
nTPM: 223.3
2502 Female, age 75, unknown 234.5
1947 Male, age 18, unknown 224.2
1795 Male, age 51, unknown 211.3
Periaquaductal grey, dorsal
nTPM: 206.2
1831 Male, age 72, unknown 217.4
2850 Male, age 76, both hemispheres 205.2
2464 Female, age 72, unknown 203.9
1840 Male, age 53, unknown 198.4
Periaquaductal grey, lateral
nTPM: 204.9
2053 Male, age 18, unknown 221.8
2140 Male, age 76, both hemispheres 197.8
2272 Male, age 74, both hemispheres 195.2
Pretectal area
nTPM: 208.8
1815 Male, age 53, unknown 220.3
2407 Male, age 75, both hemispheres 217.8
2825 Male, age 18, unknown 216.1
1816 Male, age 51, unknown 211.9
2316 Male, age 76, right hemisphere 211.3
1944 Female, age 72, unknown 210.9
1817 Female, age 42, unknown 207.1
2007 Male, age 72, unknown 207.1
2224 Female, age 72, unknown 198.5
2273 Male, age 74, both hemispheres 197.8
2667 Female, age 75, unknown 197.8
Red nucleus
nTPM: 239.0
2588 Male, age 74, left hemisphere 268.9
2503 Female, age 72, unknown 262.8
2584 Male, age 75, left hemisphere 253.8
1821 Female, age 72, unknown 251.8
2725 Female, age 75, unknown 243.2
1865 Male, age 51, unknown 236.4
1904 Male, age 53, unknown 232.0
2823 Male, age 76, right hemisphere 229.5
1954 Female, age 42, unknown 229.4
2769 Male, age 72, unknown 224.6
2227 Male, age 72, unknown 222.1
2785 Male, age 18, unknown 214.0
Substantia nigra
nTPM: 229.4
2241 Male, age 72, unknown 241.7
2699 Male, age 18, unknown 236.7
2409 Female, age 72, unknown 233.4
1851 Male, age 51, unknown 233.3
2590 Female, age 75, unknown 233.1
2665 Male, age 74, both hemispheres 229.2
2583 Male, age 75, right hemisphere 226.4
1941 Male, age 53, unknown 222.9
1889 Female, age 72, unknown 222.4
1916 Female, age 42, unknown 214.8
Superior colliculus
nTPM: 217.5
2587 Male, age 74, left hemisphere 245.3
1995 Male, age 72, unknown 227.9
1913 Female, age 42, unknown 224.4
1839 Male, age 51, unknown 216.9
2664 Male, age 75, both hemispheres 216.6
2261 Male, age 18, unknown 215.4
2668 Female, age 75, unknown 211.0
1796 Male, age 53, unknown 207.5
2087 Female, age 72, unknown 205.8
1895 Male, age 76, right hemisphere 204.2
Ventral tegmental area
nTPM: 220.3
2223 Female, age 72, unknown 231.0
1942 Male, age 51, unknown 225.2
2410 Female, age 72, unknown 221.5
2021 Male, age 53, unknown 217.9
1915 Female, age 42, unknown 216.6
2218 Male, age 76, both hemispheres 209.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 326.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 326.4
Samples: 139

Max nTPM: 855.5
Min nTPM: 170.0
Std nTPM: 118.2
Median nTPM: 296.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 855.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 647.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 615.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 599.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 584.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 583.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 582.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 571.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 525.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 507.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 503.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 502.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 498.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 490.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 486.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 483.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 476.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 472.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 456.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 454.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 444.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 443.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 434.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 432.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 427.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 426.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 420.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 420.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 417.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 416.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 413.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 411.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 405.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 405.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 392.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 392.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 385.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 385.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 384.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 378.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 375.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 375.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 371.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 367.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 362.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 360.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 359.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 356.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 355.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 352.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 351.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 349.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 340.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 338.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 337.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 325.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 324.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 324.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 323.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 317.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 316.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 311.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 305.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 305.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 305.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 304.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 302.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 299.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 298.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 296.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 294.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 293.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 289.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 284.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 283.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 282.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 281.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 279.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 276.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 275.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 275.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 275.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 274.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 273.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 271.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 269.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 267.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 263.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 257.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 256.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 254.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 252.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 251.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 251.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 247.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 245.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 244.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 244.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 241.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 240.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 239.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 239.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 237.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 236.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 236.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 232.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 232.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 232.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 231.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 231.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 229.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 229.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 224.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 221.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 221.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 220.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 219.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 214.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 214.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 213.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 212.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 207.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 204.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 204.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 203.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 203.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 202.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 200.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 196.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 194.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 193.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 189.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 188.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 183.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 181.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 179.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 177.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 177.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 170.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 373.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 373.9
FF:10158-103A5 76 years, female 373.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 176.7
Pig sample Sample description nTPM
Midbrain
nTPM: 176.7
Samples: 4

Max nTPM: 292.6
Min nTPM: 113.0
Sample A Female 292.6
Sample B Female 167.6
Sample C Male 133.7
Sample D Male 113.0
Periaqueductal gray
nTPM: 138.6
Samples: 3

Max nTPM: 147.6
Min nTPM: 130.9
Sample B Female 130.9
Sample C Male 147.6
Sample D Male 137.3
Substantia nigra
nTPM: 158.4
Samples: 4

Max nTPM: 182.1
Min nTPM: 140.2
Sample A Female 182.1
Sample B Female 140.2
Sample C Male 154.3
Sample D Male 157.1
Superior colliculi
nTPM: 146.2
Samples: 4

Max nTPM: 154.4
Min nTPM: 131.0
Sample A Female 150.3
Sample B Female 131.0
Sample C Male 154.4
Sample D Male 148.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 202.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 202.1
Samples: 4

Max nTPM: 208.1
Min nTPM: 199.2
Sample A Male 200.7
Sample B Male 208.1
Sample C Female 199.2
Sample D Female 200.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.5
75198178 Antisense, RP_060502_02_B04, Mouse strain C57BL/6J (56 days, male) 0.5

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