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BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Mouse brain, Intensity
Ponsi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

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120.599
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:69.5 nTPM
HPA:69.5 nTPM
FANTOM5:454.5 Scaled Tags Per Million
Pig:60.2 nTPM
Allen mouse:4.6 Expression energy

PONS - Mouse brain profilei

Protein expression in mouse brain using immunofluorescence is reported as fluorescence intensity .

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, antibody HPA037943
Pons mean intensity 120.599
intensityi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

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FRONT BACK
Barrington's nucleus -
Koelliker-fuse nucleus -
Motor tregiminal nucleus 16.501
Parabrachial nucleus 48.034
Principle sensory trigeminal nucleus 16.016
Locus coeruleus 120.599
Pontine nucleus 17.252
Vestibular nucleus 30.204
Pontine reticular nucleus, oral 18.316
Lateral lemniscus 15.704
Superior paraolivary nucleus 13.732

PONS - HPA Brain RNA-seq
Max nTPM 69.5
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 61.6
2188 Female, age 91, both hemispheres 87.5
2301 Female, age 85, both hemispheres 69.5
2090 Male, age 80, both hemispheres 63.4
1984 Male, age 76, both hemispheres 25.9
Dorsal cochlear nucleus
nTPM: 49.9
2802 Male, age 74, right hemisphere 58.0
2187 Female, age 91, both hemispheres 52.6
2370 Male, age 61, both hemispheres 51.6
2378 Male, age 80, both hemispheres 47.5
2058 Male, age 76, both hemispheres 39.6
Dorsal tegmental nucleus
nTPM: 47.0
2083 Male, age 80, both hemispheres 56.5
2326 Male, age 74, both hemispheres 50.7
2358 Male, age 61, both hemispheres 42.0
1936 Male, age 76, left hemisphere 38.8
Dorsolateral tegmental area
nTPM: 43.9
2654 Male, age 80, both hemispheres 58.5
2337 Male, age 61, both hemispheres 57.2
2751 Female, age 85, both hemispheres 46.4
2141 Male, age 76, both hemispheres 29.5
2360 Male, age 74, both hemispheres 27.6
Kolliker-Fuse nucleus
nTPM: 57.5
2793 Female, age 91, left hemisphere 102.3
2163 Male, age 80, both hemispheres 46.5
2315 Male, age 76, right hemisphere 23.8
Lateral lemniscal nuclei
nTPM: 52.9
2320 Female, age 91, left hemisphere 77.7
2169 Male, age 76, both hemispheres 52.1
2746 Female, age 85, left hemisphere 47.9
2453 Male, age 74, right hemisphere 46.8
2036 Male, age 80, both hemispheres 40.0
Lateral parabrachial nucleus
nTPM: 61.3
2792 Male, age 76, both hemispheres 85.5
2790 Male, age 61, both hemispheres 64.0
2013 Male, age 80, both hemispheres 54.8
2139 Female, age 85, right hemisphere 41.1
Lateral vestibular nucleus
nTPM: 53.4
2311 Male, age 80, both hemispheres 56.9
2184 Male, age 76, both hemispheres 50.0
Locus coeruleus
nTPM: 30.2
2720 Male, age 74, both hemispheres 49.7
2162 Male, age 80, both hemispheres 36.1
2788 Male, age 74, unknown 30.3
2014 Male, age 55, unknown 28.6
2317 Female, age 72, unknown 27.6
2123 Female, age 91, both hemispheres 20.9
1980 Male, age 76, both hemispheres 18.4
Medial olivary nucleus
nTPM: 56.9
1943 Male, age 61, both hemispheres 64.6
2851 Male, age 80, both hemispheres 64.6
1962 Male, age 76, both hemispheres 50.8
2138 Female, age 91, both hemispheres 47.4
Medial parabrachial nucleus
nTPM: 51.5
2156 Male, age 61, both hemispheres 64.4
2854 Male, age 80, both hemispheres 54.5
2786 Male, age 76, both hemispheres 51.1
2170 Female, age 91, both hemispheres 48.6
2463 Female, age 85, right hemisphere 38.8
Medial periolivary nuclei
nTPM: 49.5
2458 Female, age 91, both hemispheres 71.6
2081 Male, age 80, both hemispheres 58.6
2063 Male, age 76, both hemispheres 41.1
2171 Female, age 85, both hemispheres 38.7
2791 Male, age 74, right hemisphere 37.4
Motor facial nucleus
nTPM: 54.5
2697 Female, age 85, both hemispheres 89.9
2327 Male, age 80, both hemispheres 56.0
2126 Male, age 61, both hemispheres 52.9
2795 Female, age 91, both hemispheres 51.0
2365 Male, age 74, right hemisphere 43.4
2062 Male, age 76, both hemispheres 34.1
Motor trigeminal nucleus
nTPM: 57.1
2321 Female, age 91, both hemispheres 69.6
2309 Male, age 76, both hemispheres 57.9
2335 Male, age 61, both hemispheres 56.1
2560 Male, age 74, both hemispheres 51.8
2079 Male, age 80, both hemispheres 50.3
Nuclei of the trapezoid body
nTPM: 46.7
2166 Male, age 80, both hemispheres 63.9
2368 Female, age 91, both hemispheres 54.6
2159 Male, age 61, both hemispheres 42.9
1983 Male, age 76, both hemispheres 42.7
2735 Female, age 85, both hemispheres 29.4
Paramedian reticular nucleus
nTPM: 49.6
2052 Male, age 76, both hemispheres 63.2
2313 Male, age 61, both hemispheres 48.8
2050 Female, age 85, both hemispheres 45.9
2057 Male, age 80, both hemispheres 40.4
Pontine nuclei
nTPM: 52.1
2319 Female, age 91, both hemispheres 78.9
1968 Male, age 76, left hemisphere 61.5
2115 Male, age 80, left hemisphere 60.0
2454 Male, age 74, left hemisphere 57.8
2109 Female, age 72, unknown 49.0
1863 Male, age 55, unknown 42.8
2787 Female, age 85, both hemispheres 38.5
2727 Male, age 61, right hemisphere 28.0
Pontine raphe nucleus
nTPM: 38.8
2853 Male, age 76, midline 39.4
2122 Female, age 85, midline 38.3
Posteroventral cochlear nucleus
nTPM: 69.5
2135 Female, age 91, both hemispheres 108.3
2341 Male, age 80, both hemispheres 78.0
2371 Male, age 61, both hemispheres 60.3
2070 Male, age 76, both hemispheres 57.6
2752 Female, age 85, both hemispheres 43.3
Principal sensory trigeminal nucleus
nTPM: 51.6
2367 Female, age 91, left hemisphere 77.0
2324 Male, age 76, both hemispheres 54.8
2008 Male, age 80, left hemisphere 39.1
2158 Male, age 61, both hemispheres 35.6
Reticular pontine nucleus, caudal
nTPM: 61.2
2457 Female, age 91, both hemispheres 72.7
2559 Male, age 74, both hemispheres 60.5
2092 Male, age 76, both hemispheres 57.7
2332 Male, age 80, right hemisphere 53.9
Reticular pontine nucleus, oral
nTPM: 57.7
2366 Female, age 91, both hemispheres 101.2
2167 Male, age 76, both hemispheres 54.7
1939 Male, age 80, both hemispheres 49.6
2012 Female, age 85, both hemispheres 44.2
2361 Male, age 74, both hemispheres 38.8
Reticulotegmental nucleus
nTPM: 51.7
2322 Female, age 91, both hemispheres 56.1
2452 Male, age 74, both hemispheres 55.6
2333 Male, age 80, both hemispheres 52.1
2325 Male, age 76, both hemispheres 42.8
Spinal trigeminal nucleus, oral
nTPM: 43.6
2164 Male, age 80, both hemispheres 52.5
1978 Male, age 76, both hemispheres 48.8
2737 Female, age 85, both hemispheres 29.6
Subcoeruleus area
nTPM: 49.4
2369 Female, age 85, left hemisphere 57.9
2089 Male, age 76, left hemisphere 55.4
2451 Male, age 74, both hemispheres 50.0
1958 Male, age 80, both hemispheres 43.9
2323 Female, age 91, left hemisphere 40.0
Superior olive
nTPM: 57.1
2561 Female, age 91, both hemispheres 76.0
2020 Male, age 76, both hemispheres 70.1
2329 Male, age 80, right hemisphere 62.4
1875 Female, age 85, both hemispheres 42.1
2364 Male, age 74, right hemisphere 34.8
Superior vestibular nucleus
nTPM: 34.6
2015 Male, age 80, both hemispheres 42.2
2383 Male, age 74, both hemispheres 32.0
2061 Male, age 76, both hemispheres 29.7
Ventral periolivary nuclei
nTPM: 56.5
2023 Male, age 76, both hemispheres 72.7
2794 Female, age 91, left hemisphere 63.3
2165 Male, age 80, both hemispheres 52.6
2130 Female, age 85, both hemispheres 37.6
Ventrolateral tegmental area, A5 NE cell group
nTPM: 52.5
2840 Female, age 85, both hemispheres 59.6
1959 Male, age 76, both hemispheres 54.2
2161 Male, age 80, both hemispheres 54.1
2456 Female, age 91, both hemispheres 52.5
2359 Male, age 61, both hemispheres 51.8
2449 Male, age 74, both hemispheres 43.0

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

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Max Scaled Tags Per Million 454.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 430.7
FF:10182-103D2 60 years, female 508.3
FF:10165-103B3 76 years, female 353.1
Pons
Scaled Tags Per Million: 454.5
FF:10033-101E6 18-54 years, mixed 454.5

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
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Average nTPM 60.2
Pig sample Sample description nTPM
Pons
nTPM: 60.2
Samples: 4

Max nTPM: 69.1
Min nTPM: 54.0
Sample A Female 54.0
Sample B Female 56.5
Sample C Male 61.3
Sample D Male 69.1

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

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Max Expression energy 4.6
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 4.6
322956 Antisense, RP_040609_01_A09, Mouse strain C57BL/6J (56 days, male) 4.6
275675 Antisense, RP_040609_01_A09, Mouse strain C57BL/6J (56 days, male) 0.6

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.