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FNBP1
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BRAIN PONS AND MEDULLA Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
PONS AND MEDULLA - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:67.6 nTPM
HPA:67.6 nTPM
FANTOM5:114.8 Scaled Tags Per Million
Pig:79.0 nTPM
Mouse:118.3 nTPM
Allen mouse:8.5 Expression energy

PONS AND MEDULLA - HPA Brain RNA-seq
Max nTPM 67.6
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 62.0
2301 Female, age 85, both hemispheres 67.5
2188 Female, age 91, both hemispheres 62.5
2090 Male, age 80, both hemispheres 59.7
1984 Male, age 76, both hemispheres 58.3
Area postrema
nTPM: 65.3
2306 Male, age 80, both hemispheres 73.8
2799 Male, age 61, both hemispheres 64.1
2054 Male, age 76, both hemispheres 57.9
Cuneate nuclei
nTPM: 60.2
2381 Male, age 80, both hemispheres 65.3
2376 Male, age 61, both hemispheres 58.1
2131 Male, age 76, both hemispheres 57.2
Dorsal cochlear nucleus
nTPM: 57.4
2058 Male, age 76, both hemispheres 61.0
2378 Male, age 80, both hemispheres 59.8
2802 Male, age 74, right hemisphere 56.3
2187 Female, age 91, both hemispheres 55.6
2370 Male, age 61, both hemispheres 54.4
Dorsal medullary reticular nucleus
nTPM: 61.4
2373 Male, age 61, both hemispheres 66.3
2088 Male, age 76, both hemispheres 59.7
2040 Female, age 85, both hemispheres 58.1
Dorsal motor vagal complex
nTPM: 57.7
2797 Male, age 61, both hemispheres 65.7
2185 Male, age 76, both hemispheres 62.3
2807 Female, age 85, both hemispheres 57.9
2643 Male, age 74, both hemispheres 57.8
2813 Female, age 72, unknown 57.4
2000 Male, age 74, unknown 56.2
2133 Female, age 91, both hemispheres 55.3
2844 Male, age 55, unknown 49.3
Dorsal tegmental nucleus
nTPM: 53.0
2083 Male, age 80, both hemispheres 57.7
1936 Male, age 76, left hemisphere 53.7
2326 Male, age 74, both hemispheres 53.1
2358 Male, age 61, both hemispheres 47.3
Dorsolateral tegmental area
nTPM: 52.8
2654 Male, age 80, both hemispheres 58.9
2751 Female, age 85, both hemispheres 57.9
2337 Male, age 61, both hemispheres 52.7
2141 Male, age 76, both hemispheres 50.4
2360 Male, age 74, both hemispheres 44.0
Gigantocellular reticular nuclei, medullary
nTPM: 58.4
2314 Male, age 61, both hemispheres 73.2
1876 Female, age 85, both hemispheres 60.1
2387 Female, age 91, both hemispheres 59.9
2022 Male, age 76, right hemisphere 57.2
2310 Male, age 80, both hemispheres 54.8
2462 Male, age 74, both hemispheres 45.5
Gigantocellular reticular nuclei, pars
nTPM: 58.8
2336 Male, age 61, both hemispheres 63.0
2330 Male, age 80, both hemispheres 61.0
2706 Male, age 80, both hemispheres 59.6
2084 Female, age 85, both hemispheres 57.2
2168 Male, age 76, both hemispheres 53.2
Inferior olive
nTPM: 62.8
2178 Male, age 61, both hemispheres 71.4
2628 Female, age 91, both hemispheres 66.7
2379 Male, age 80, both hemispheres 61.2
2563 Male, age 74, both hemispheres 57.7
2085 Female, age 85, both hemispheres 56.7
Kolliker-Fuse nucleus
nTPM: 62.8
2793 Female, age 91, left hemisphere 67.5
2315 Male, age 76, right hemisphere 60.8
2163 Male, age 80, both hemispheres 59.9
Lateral lemniscal nuclei
nTPM: 55.8
2320 Female, age 91, left hemisphere 63.2
2036 Male, age 80, both hemispheres 55.2
2746 Female, age 85, left hemisphere 54.8
2169 Male, age 76, both hemispheres 53.9
2453 Male, age 74, right hemisphere 51.7
Lateral medullary reticular nucleus
nTPM: 63.0
2374 Male, age 61, both hemispheres 75.8
2852 Male, age 80, both hemispheres 66.2
2190 Female, age 85, both hemispheres 62.4
2044 Male, age 76, both hemispheres 59.2
2804 Female, age 91, both hemispheres 58.0
2305 Male, age 74, both hemispheres 56.5
Lateral parabrachial nucleus
nTPM: 60.3
2792 Male, age 76, both hemispheres 68.7
2013 Male, age 80, both hemispheres 60.2
2790 Male, age 61, both hemispheres 56.5
2139 Female, age 85, right hemisphere 55.8
Lateral vestibular nucleus
nTPM: 60.2
2184 Male, age 76, both hemispheres 61.9
2311 Male, age 80, both hemispheres 58.5
Locus coeruleus
nTPM: 49.6
1980 Male, age 76, both hemispheres 54.4
2162 Male, age 80, both hemispheres 52.6
2720 Male, age 74, both hemispheres 52.3
2317 Female, age 72, unknown 51.2
2788 Male, age 74, unknown 46.7
2123 Female, age 91, both hemispheres 46.0
2014 Male, age 55, unknown 44.3
Medial olivary nucleus
nTPM: 65.8
1943 Male, age 61, both hemispheres 73.5
2851 Male, age 80, both hemispheres 66.9
1962 Male, age 76, both hemispheres 61.8
2138 Female, age 91, both hemispheres 61.1
Medial parabrachial nucleus
nTPM: 56.7
2786 Male, age 76, both hemispheres 58.5
2156 Male, age 61, both hemispheres 57.8
2463 Female, age 85, right hemisphere 56.7
2854 Male, age 80, both hemispheres 56.7
2170 Female, age 91, both hemispheres 54.0
Medial periolivary nuclei
nTPM: 54.3
2458 Female, age 91, both hemispheres 60.4
2081 Male, age 80, both hemispheres 56.5
2171 Female, age 85, both hemispheres 52.9
2791 Male, age 74, right hemisphere 51.6
2063 Male, age 76, both hemispheres 49.9
Medial vestibular nucleus
nTPM: 57.8
2803 Female, age 91, both hemispheres 61.5
2624 Male, age 61, both hemispheres 61.4
2134 Male, age 76, both hemispheres 60.5
2093 Male, age 80, both hemispheres 59.7
2801 Male, age 74, both hemispheres 54.9
2743 Female, age 85, both hemispheres 48.6
Motor facial nucleus
nTPM: 57.1
2697 Female, age 85, both hemispheres 66.7
2126 Male, age 61, both hemispheres 59.2
2795 Female, age 91, both hemispheres 57.8
2327 Male, age 80, both hemispheres 55.5
2365 Male, age 74, right hemisphere 54.0
2062 Male, age 76, both hemispheres 49.6
Motor hypoglossal nucleus
nTPM: 61.4
2461 Male, age 61, both hemispheres 69.2
2182 Male, age 80, both hemispheres 62.3
2132 Female, age 85, both hemispheres 61.1
2125 Female, age 91, both hemispheres 58.3
2277 Male, age 76, both hemispheres 56.0
Motor trigeminal nucleus
nTPM: 55.8
2309 Male, age 76, both hemispheres 60.8
2321 Female, age 91, both hemispheres 59.8
2079 Male, age 80, both hemispheres 54.3
2560 Male, age 74, both hemispheres 53.2
2335 Male, age 61, both hemispheres 50.9
Nuclei of the trapezoid body
nTPM: 54.8
2166 Male, age 80, both hemispheres 58.9
2159 Male, age 61, both hemispheres 57.6
2368 Female, age 91, both hemispheres 57.0
2735 Female, age 85, both hemispheres 50.3
1983 Male, age 76, both hemispheres 50.1
Nucleus ambiguus
nTPM: 59.0
2071 Male, age 76, both hemispheres 64.5
2096 Female, age 85, both hemispheres 53.5
Nucleus cuneatus
nTPM: 63.1
2380 Male, age 80, both hemispheres 68.3
2805 Female, age 91, both hemispheres 65.3
2808 Female, age 85, both hemispheres 65.0
2100 Male, age 76, both hemispheres 63.2
2562 Male, age 61, both hemispheres 58.4
2564 Male, age 74, both hemispheres 58.3
Nucleus gracilis
nTPM: 67.6
2382 Male, age 80, both hemispheres 72.5
2299 Female, age 85, both hemispheres 66.4
2627 Male, age 74, both hemispheres 63.9
Nucleus raphe magnus
nTPM: 54.1
2328 Male, age 80, both hemispheres 61.1
2459 Female, age 91, both hemispheres 56.4
2160 Male, age 61, both hemispheres 52.5
2455 Male, age 74, both hemispheres 52.3
2172 Female, age 85, both hemispheres 51.4
2051 Male, age 76, both hemispheres 50.9
Nucleus raphe obscurus
nTPM: 66.4
2142 Male, age 76, midline 71.7
2845 Female, age 85, midline 64.4
2800 Male, age 61, midline 63.2
Nucleus raphe pallidus
nTPM: 60.9
1924 Male, age 61, midline 63.5
2145 Male, age 76, midline 62.1
2183 Male, age 80, midline 56.9
Nucleus tractus solitarii
nTPM: 51.6
2656 Male, age 76, both hemispheres 60.2
2307 Male, age 80, both hemispheres 52.0
2191 Female, age 85, both hemispheres 50.2
2144 Female, age 91, right hemisphere 44.0
Paramedian reticular nucleus
nTPM: 54.7
2057 Male, age 80, both hemispheres 58.6
2052 Male, age 76, both hemispheres 55.1
2050 Female, age 85, both hemispheres 52.6
2313 Male, age 61, both hemispheres 52.6
Parvicellular reticular nuclei
nTPM: 56.0
2095 Male, age 76, both hemispheres 58.7
2119 Male, age 80, both hemispheres 57.6
2558 Male, age 74, both hemispheres 51.7
Parvicellular reticular nuclei, medullary
nTPM: 57.1
2189 Female, age 91, both hemispheres 58.4
2091 Female, age 85, both hemispheres 57.4
2181 Male, age 80, left hemisphere 55.4
Peritrigeminal nucleus
nTPM: 60.1
2136 Male, age 76, both hemispheres 63.3
2179 Male, age 61, both hemispheres 60.6
2067 Female, age 85, both hemispheres 56.5
Pontine nuclei
nTPM: 56.5
2319 Female, age 91, both hemispheres 63.2
2454 Male, age 74, left hemisphere 58.8
2115 Male, age 80, left hemisphere 58.2
1863 Male, age 55, unknown 57.6
2109 Female, age 72, unknown 55.6
1968 Male, age 76, left hemisphere 55.1
2787 Female, age 85, both hemispheres 53.0
2727 Male, age 61, right hemisphere 51.0
Pontine raphe nucleus
nTPM: 50.2
2853 Male, age 76, midline 50.6
2122 Female, age 85, midline 49.8
Posteroventral cochlear nucleus
nTPM: 60.4
2135 Female, age 91, both hemispheres 68.9
2341 Male, age 80, both hemispheres 64.1
2070 Male, age 76, both hemispheres 63.9
2371 Male, age 61, both hemispheres 55.5
2752 Female, age 85, both hemispheres 49.6
Prepositus hypoglossal nucleus
nTPM: 53.5
2855 Female, age 85, right hemisphere 55.0
2086 Male, age 80, both hemispheres 52.0
Principal sensory trigeminal nucleus
nTPM: 58.3
2324 Male, age 76, both hemispheres 65.5
2367 Female, age 91, left hemisphere 61.7
2158 Male, age 61, both hemispheres 53.2
2008 Male, age 80, left hemisphere 52.9
Reticular pontine nucleus, caudal
nTPM: 56.9
2457 Female, age 91, both hemispheres 58.8
2092 Male, age 76, both hemispheres 57.6
2559 Male, age 74, both hemispheres 56.1
2332 Male, age 80, right hemisphere 55.1
Reticular pontine nucleus, oral
nTPM: 57.5
2366 Female, age 91, both hemispheres 72.4
2012 Female, age 85, both hemispheres 56.5
1939 Male, age 80, both hemispheres 56.1
2167 Male, age 76, both hemispheres 55.0
2361 Male, age 74, both hemispheres 47.6
Reticulotegmental nucleus
nTPM: 55.7
2333 Male, age 80, both hemispheres 58.7
2322 Female, age 91, both hemispheres 57.9
2452 Male, age 74, both hemispheres 54.3
2325 Male, age 76, both hemispheres 51.8
Spinal trigeminal nucleus, caudal
nTPM: 61.8
2312 Male, age 61, both hemispheres 65.6
2308 Male, age 80, both hemispheres 64.6
2390 Female, age 91, both hemispheres 63.1
2642 Male, age 74, both hemispheres 59.1
2447 Male, age 76, both hemispheres 56.7
Spinal trigeminal nucleus, interpolar
nTPM: 59.0
2625 Male, age 61, both hemispheres 71.1
2389 Female, age 91, both hemispheres 58.2
2066 Male, age 76, right hemisphere 56.6
2386 Female, age 85, both hemispheres 55.8
2033 Male, age 80, both hemispheres 53.2
Spinal trigeminal nucleus, oral
nTPM: 56.8
2164 Male, age 80, both hemispheres 61.1
2737 Female, age 85, both hemispheres 54.7
1978 Male, age 76, both hemispheres 54.6
Spinal vestibular nucleus
nTPM: 60.4
2748 Male, age 76, both hemispheres 66.9
2806 Female, age 85, both hemispheres 62.6
2186 Female, age 91, both hemispheres 61.1
2384 Male, age 74, both hemispheres 60.3
2780 Male, age 80, both hemispheres 56.1
2796 Male, age 61, both hemispheres 55.7
Subcoeruleus area
nTPM: 56.0
2369 Female, age 85, left hemisphere 65.5
2089 Male, age 76, left hemisphere 57.8
1958 Male, age 80, both hemispheres 53.2
2451 Male, age 74, both hemispheres 51.8
2323 Female, age 91, left hemisphere 51.6
Superior olive
nTPM: 57.0
2329 Male, age 80, right hemisphere 60.5
2561 Female, age 91, both hemispheres 60.3
1875 Female, age 85, both hemispheres 56.2
2020 Male, age 76, both hemispheres 56.2
2364 Male, age 74, right hemisphere 52.1
Superior vestibular nucleus
nTPM: 54.1
2061 Male, age 76, both hemispheres 59.5
2015 Male, age 80, both hemispheres 54.9
2383 Male, age 74, both hemispheres 48.0
Ventral medullary reticular nucleus
nTPM: 65.3
2372 Male, age 61, both hemispheres 67.9
2060 Male, age 76, both hemispheres 62.7
Ventral periolivary nuclei
nTPM: 57.1
2023 Male, age 76, both hemispheres 61.2
2130 Female, age 85, both hemispheres 56.8
2165 Male, age 80, both hemispheres 56.6
2794 Female, age 91, left hemisphere 53.6
Ventrolateral medulla, A1-C1 cell groups
nTPM: 59.6
2118 Male, age 80, both hemispheres 62.8
2180 Male, age 61, both hemispheres 62.8
1986 Male, age 76, both hemispheres 61.4
2302 Female, age 91, both hemispheres 55.9
2741 Female, age 85, both hemispheres 55.0
Ventrolateral tegmental area, A5 NE cell group
nTPM: 56.9
2840 Female, age 85, both hemispheres 60.3
2456 Female, age 91, both hemispheres 60.1
1959 Male, age 76, both hemispheres 57.6
2359 Male, age 61, both hemispheres 56.6
2161 Male, age 80, both hemispheres 55.3
2449 Male, age 74, both hemispheres 51.8

PONS AND MEDULLA - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 114.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 114.8
FF:10182-103D2 60 years, female 134.1
FF:10165-103B3 76 years, female 95.4
Medulla oblongata
Scaled Tags Per Million: 103.8
FF:10174-103C3 60 years, female 120.0
FF:10038-101F2 18-64 years, mixed 95.8
FF:10155-103A2 76 years, female 95.6
Pons
Scaled Tags Per Million: 78.4
FF:10033-101E6 18-54 years, mixed 78.4

PONS AND MEDULLA - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 79.0
Pig sample Sample description nTPM
Medulla oblongata
nTPM: 79.0
Samples: 4

Max nTPM: 82.0
Min nTPM: 74.9
Sample A Female 82.0
Sample B Female 78.6
Sample C Male 80.6
Sample D Male 74.9
Pons
nTPM: 62.2
Samples: 4

Max nTPM: 76.0
Min nTPM: 55.3
Sample A Female 55.3
Sample B Female 58.5
Sample C Male 58.8
Sample D Male 76.0

PONS AND MEDULLA - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 118.3
Mouse sample Sample description nTPM
Pons and medulla
nTPM: 118.3
Samples: 4

Max nTPM: 121.9
Min nTPM: 110.7
Sample A Male 121.9
Sample B Male 120.4
Sample C Female 110.7
Sample D Female 120.0

PONS AND MEDULLA - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 8.5
Allen experiment id Experiment description Expression energy
Medulla oblongata
Expression energy: 8.5
75695662 Antisense, RP_060518_04_D01, Mouse strain C57BL/6J (56 days, male) 15.1
73906077 Antisense, RP_051212_04_F08, Mouse strain C57BL/6J (56 days, male) 1.9
Pons
Expression energy: 7.7
75695662 Antisense, RP_060518_04_D01, Mouse strain C57BL/6J (56 days, male) 14.1
73906077 Antisense, RP_051212_04_F08, Mouse strain C57BL/6J (56 days, male) 1.3

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