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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:189.6 nTPM
HPA:189.6 nTPM
GTEx:223.5 nTPM
FANTOM5:499.9 Scaled Tags Per Million
Pig:758.0 nTPM
Mouse:994.2 nTPM
Allen mouse:6.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 189.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 180.6
2019 Male, age 18, unknown 187.9
1827 Male, age 72, unknown 186.2
2411 Female, age 72, unknown 185.0
1870 Female, age 42, unknown 181.9
2586 Male, age 75, left hemisphere 179.6
2828 Female, age 72, unknown 178.1
1833 Male, age 53, unknown 177.3
2666 Male, age 74, left hemisphere 177.1
1830 Male, age 51, unknown 176.8
2219 Male, age 76, both hemispheres 176.0
Dorsal raphe nucleus
nTPM: 182.2
2298 Female, age 72, unknown 191.7
2047 Male, age 72, unknown 181.6
1828 Male, age 53, unknown 181.4
2750 Male, age 76, both hemispheres 180.3
2016 Female, age 72, unknown 175.8
Inferior colliculus
nTPM: 189.6
2097 Female, age 72, unknown 202.1
1890 Male, age 53, unknown 192.7
1848 Female, age 42, unknown 184.3
2849 Male, age 72, unknown 179.2
Median raphe nucleus
nTPM: 175.2
2220 Male, age 76, midline 175.2
Pedunculopontine tegmental nucleus
nTPM: 183.6
1921 Female, age 85, both hemispheres 185.2
2334 Male, age 80, both hemispheres 184.7
2338 Male, age 61, both hemispheres 181.0
Periaquaductal grey, anterior
nTPM: 182.2
1947 Male, age 18, unknown 185.3
1795 Male, age 51, unknown 181.3
2502 Female, age 75, unknown 180.0
Periaquaductal grey, dorsal
nTPM: 177.4
1840 Male, age 53, unknown 179.4
2464 Female, age 72, unknown 179.1
1831 Male, age 72, unknown 177.3
2850 Male, age 76, both hemispheres 173.9
Periaquaductal grey, lateral
nTPM: 177.9
2053 Male, age 18, unknown 181.9
2272 Male, age 74, both hemispheres 179.5
2140 Male, age 76, both hemispheres 172.2
Pretectal area
nTPM: 187.5
1816 Male, age 51, unknown 201.3
2007 Male, age 72, unknown 200.7
1817 Female, age 42, unknown 195.6
1944 Female, age 72, unknown 192.7
1815 Male, age 53, unknown 188.1
2667 Female, age 75, unknown 185.4
2224 Female, age 72, unknown 183.2
2273 Male, age 74, both hemispheres 182.8
2316 Male, age 76, right hemisphere 178.4
2825 Male, age 18, unknown 177.4
2407 Male, age 75, both hemispheres 177.3
Red nucleus
nTPM: 184.1
1821 Female, age 72, unknown 195.7
2725 Female, age 75, unknown 187.7
2503 Female, age 72, unknown 186.5
2785 Male, age 18, unknown 185.7
2588 Male, age 74, left hemisphere 185.3
2769 Male, age 72, unknown 182.5
1865 Male, age 51, unknown 182.4
2227 Male, age 72, unknown 182.4
2584 Male, age 75, left hemisphere 182.0
2823 Male, age 76, right hemisphere 181.2
1954 Female, age 42, unknown 179.2
1904 Male, age 53, unknown 178.5
Substantia nigra
nTPM: 184.7
1889 Female, age 72, unknown 194.0
1941 Male, age 53, unknown 189.7
1851 Male, age 51, unknown 187.2
2241 Male, age 72, unknown 185.5
1916 Female, age 42, unknown 185.3
2665 Male, age 74, both hemispheres 184.8
2590 Female, age 75, unknown 183.2
2409 Female, age 72, unknown 182.3
2583 Male, age 75, right hemisphere 180.1
2699 Male, age 18, unknown 175.3
Superior colliculus
nTPM: 183.2
2587 Male, age 74, left hemisphere 188.3
2087 Female, age 72, unknown 187.6
1796 Male, age 53, unknown 185.6
2261 Male, age 18, unknown 185.5
1895 Male, age 76, right hemisphere 185.3
2668 Female, age 75, unknown 183.9
1913 Female, age 42, unknown 181.3
1839 Male, age 51, unknown 180.5
1995 Male, age 72, unknown 178.1
2664 Male, age 75, both hemispheres 175.9
Ventral tegmental area
nTPM: 182.7
2410 Female, age 72, unknown 186.7
2223 Female, age 72, unknown 186.6
1915 Female, age 42, unknown 186.1
2218 Male, age 76, both hemispheres 180.7
1942 Male, age 51, unknown 178.2
2021 Male, age 53, unknown 178.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 223.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 223.5
Samples: 139

Max nTPM: 640.6
Min nTPM: 111.6
Std nTPM: 70.0
Median nTPM: 209.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 640.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 459.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 409.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 380.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 365.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 362.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 342.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 341.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 337.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 327.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 327.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 326.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 321.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 320.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 317.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 306.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 300.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 288.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 288.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 285.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 282.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 272.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 272.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 270.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 268.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 267.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 265.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 264.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 263.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 263.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 263.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 255.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 250.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 250.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 249.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 248.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 246.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 245.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 244.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 242.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 241.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 239.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 239.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 235.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 235.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 234.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 232.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 232.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 230.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 229.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 227.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 227.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 226.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 226.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 225.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 222.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 221.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 220.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 218.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 216.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 215.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 215.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 214.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 214.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 214.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 213.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 211.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 209.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 209.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 209.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 208.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 208.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 207.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 206.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 205.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 205.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 204.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 202.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 201.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 201.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 201.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 200.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 199.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 199.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 196.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 196.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 196.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 194.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 192.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 192.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 192.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 191.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 190.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 190.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 190.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 190.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 188.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 188.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 188.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 188.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 186.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 185.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 181.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 181.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 180.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 179.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 178.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 175.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 174.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 174.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 174.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 174.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 172.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 171.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 171.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 170.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 166.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 165.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 164.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 157.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 157.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 154.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 153.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 152.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 152.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 152.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 151.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 149.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 148.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 146.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 143.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 143.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 142.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 141.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 135.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 132.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 131.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 115.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 111.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 499.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 499.9
FF:10158-103A5 76 years, female 499.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 758.0
Pig sample Sample description nTPM
Midbrain
nTPM: 615.3
Samples: 4

Max nTPM: 745.4
Min nTPM: 519.5
Sample A Female 585.6
Sample B Female 519.5
Sample C Male 745.4
Sample D Male 610.8
Periaqueductal gray
nTPM: 404.6
Samples: 3

Max nTPM: 448.8
Min nTPM: 357.5
Sample B Female 407.6
Sample C Male 448.8
Sample D Male 357.5
Substantia nigra
nTPM: 501.6
Samples: 4

Max nTPM: 714.8
Min nTPM: 363.4
Sample A Female 714.8
Sample B Female 443.7
Sample C Male 484.4
Sample D Male 363.4
Superior colliculi
nTPM: 758.0
Samples: 4

Max nTPM: 896.9
Min nTPM: 612.1
Sample A Female 856.6
Sample B Female 666.5
Sample C Male 896.9
Sample D Male 612.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 994.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 994.2
Samples: 4

Max nTPM: 1012.6
Min nTPM: 976.3
Sample A Male 1012.6
Sample B Male 998.0
Sample C Female 976.3
Sample D Female 990.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 6.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 6.5
69782139 Antisense, RP_050505_02_D07, Mouse strain C57BL/6J (56 days, male) 6.5

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