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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:79.4 nTPM
HPA:79.4 nTPM
GTEx:67.9 nTPM
FANTOM5:183.3 Scaled Tags Per Million
Pig:29.8 nTPM
Mouse:38.1 nTPM
Allen mouse:0.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 79.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 66.8
1830 Male, age 51, unknown 85.7
1833 Male, age 53, unknown 81.5
1870 Female, age 42, unknown 78.7
2411 Female, age 72, unknown 77.6
2019 Male, age 18, unknown 77.4
2828 Female, age 72, unknown 59.7
2586 Male, age 75, left hemisphere 55.3
2666 Male, age 74, left hemisphere 54.5
1827 Male, age 72, unknown 52.5
2219 Male, age 76, both hemispheres 45.6
Dorsal raphe nucleus
nTPM: 57.2
2750 Male, age 76, both hemispheres 74.0
2016 Female, age 72, unknown 57.4
1828 Male, age 53, unknown 56.6
2298 Female, age 72, unknown 51.4
2047 Male, age 72, unknown 46.4
Inferior colliculus
nTPM: 50.4
1848 Female, age 42, unknown 56.7
2849 Male, age 72, unknown 51.5
1890 Male, age 53, unknown 51.0
2097 Female, age 72, unknown 42.6
Median raphe nucleus
nTPM: 58.6
2220 Male, age 76, midline 58.6
Pedunculopontine tegmental nucleus
nTPM: 70.0
2338 Male, age 61, both hemispheres 87.4
2334 Male, age 80, both hemispheres 68.5
1921 Female, age 85, both hemispheres 54.0
Periaquaductal grey, anterior
nTPM: 48.9
2502 Female, age 75, unknown 55.9
1947 Male, age 18, unknown 47.1
1795 Male, age 51, unknown 43.7
Periaquaductal grey, dorsal
nTPM: 49.1
2850 Male, age 76, both hemispheres 55.8
2464 Female, age 72, unknown 52.4
1831 Male, age 72, unknown 47.7
1840 Male, age 53, unknown 40.6
Periaquaductal grey, lateral
nTPM: 54.4
2272 Male, age 74, both hemispheres 58.8
2053 Male, age 18, unknown 54.0
2140 Male, age 76, both hemispheres 50.4
Pretectal area
nTPM: 52.3
2407 Male, age 75, both hemispheres 60.5
1815 Male, age 53, unknown 60.3
2273 Male, age 74, both hemispheres 58.9
2316 Male, age 76, right hemisphere 57.2
1817 Female, age 42, unknown 54.8
2825 Male, age 18, unknown 53.5
2224 Female, age 72, unknown 52.9
2007 Male, age 72, unknown 51.0
2667 Female, age 75, unknown 49.0
1944 Female, age 72, unknown 40.8
1816 Male, age 51, unknown 36.7
Red nucleus
nTPM: 79.4
1865 Male, age 51, unknown 99.7
1904 Male, age 53, unknown 89.3
2769 Male, age 72, unknown 87.6
2227 Male, age 72, unknown 87.4
1821 Female, age 72, unknown 86.5
2785 Male, age 18, unknown 80.9
2823 Male, age 76, right hemisphere 79.7
1954 Female, age 42, unknown 76.2
2503 Female, age 72, unknown 72.5
2584 Male, age 75, left hemisphere 67.5
2725 Female, age 75, unknown 62.9
2588 Male, age 74, left hemisphere 62.2
Substantia nigra
nTPM: 60.8
2590 Female, age 75, unknown 76.5
2699 Male, age 18, unknown 69.6
1851 Male, age 51, unknown 67.8
2583 Male, age 75, right hemisphere 67.3
2409 Female, age 72, unknown 62.7
1889 Female, age 72, unknown 57.8
2241 Male, age 72, unknown 53.6
2665 Male, age 74, both hemispheres 53.3
1916 Female, age 42, unknown 50.1
1941 Male, age 53, unknown 49.4
Superior colliculus
nTPM: 58.9
1913 Female, age 42, unknown 82.4
1995 Male, age 72, unknown 80.8
2587 Male, age 74, left hemisphere 68.0
1839 Male, age 51, unknown 59.8
1895 Male, age 76, right hemisphere 57.9
2664 Male, age 75, both hemispheres 51.2
1796 Male, age 53, unknown 51.1
2668 Female, age 75, unknown 50.6
2087 Female, age 72, unknown 46.1
2261 Male, age 18, unknown 41.6
Ventral tegmental area
nTPM: 63.8
2223 Female, age 72, unknown 80.0
2410 Female, age 72, unknown 69.1
2021 Male, age 53, unknown 62.9
2218 Male, age 76, both hemispheres 59.1
1915 Female, age 42, unknown 56.0
1942 Male, age 51, unknown 55.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 67.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 67.9
Samples: 139

Max nTPM: 159.6
Min nTPM: 19.8
Std nTPM: 23.9
Median nTPM: 62.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 159.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 135.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 128.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 125.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 123.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 120.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 119.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 116.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 115.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 114.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 113.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 106.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 106.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 104.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 104.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 100.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 96.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 93.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 93.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 89.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 89.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 88.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 88.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 87.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 87.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 86.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 85.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 84.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 83.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 81.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 81.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 81.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 80.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 80.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 79.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 79.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 79.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 78.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 77.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 77.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 77.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 77.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 76.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 76.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 74.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 73.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 73.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 73.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 73.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 73.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 72.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 72.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 70.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 70.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 69.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 66.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 66.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 65.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 65.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 65.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 65.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 64.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 64.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 64.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 64.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 64.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 64.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 63.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 63.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 62.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 62.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 62.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 61.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 61.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 61.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 60.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 60.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 60.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 58.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 58.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 58.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 58.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 58.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 57.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 57.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 57.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 57.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 57.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 56.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 55.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 55.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 55.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 55.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 55.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 54.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 54.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 54.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 54.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 53.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 53.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 53.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 53.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 52.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 51.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 51.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 51.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 49.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 49.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 49.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 48.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 48.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 48.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 48.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 47.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 46.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 46.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 46.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 45.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 45.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 45.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 44.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 44.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 43.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 43.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 42.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 41.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 41.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 41.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 40.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 40.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 40.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 40.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 39.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 39.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 35.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 33.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 30.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 26.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 19.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 183.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 183.3
FF:10158-103A5 76 years, female 183.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 29.8
Pig sample Sample description nTPM
Midbrain
nTPM: 25.9
Samples: 4

Max nTPM: 36.4
Min nTPM: 17.8
Sample A Female 36.4
Sample B Female 28.3
Sample C Male 21.2
Sample D Male 17.8
Periaqueductal gray
nTPM: 25.9
Samples: 3

Max nTPM: 27.6
Min nTPM: 24.2
Sample B Female 27.6
Sample C Male 25.8
Sample D Male 24.2
Substantia nigra
nTPM: 29.8
Samples: 4

Max nTPM: 33.3
Min nTPM: 24.9
Sample A Female 33.3
Sample B Female 24.9
Sample C Male 29.6
Sample D Male 31.5
Superior colliculi
nTPM: 26.6
Samples: 4

Max nTPM: 33.1
Min nTPM: 20.6
Sample A Female 33.1
Sample B Female 20.6
Sample C Male 25.8
Sample D Male 26.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 38.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 38.2
Samples: 4

Max nTPM: 42.9
Min nTPM: 35.1
Sample A Male 42.9
Sample B Male 37.4
Sample C Female 35.1
Sample D Female 37.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.3
68269586 Antisense, RP_041129_01_H03, Mouse strain C57BL/6J (56 days, male) 0.3

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