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BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:266.1 nTPM
HPA:266.1 nTPM
FANTOM5:452.5 Scaled Tags Per Million
Pig:407.5 nTPM
Allen mouse:12.9 Expression energy

PONS - HPA Brain RNA-seq
Max nTPM 266.1
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 118.4
1984 Male, age 76, both hemispheres 144.5
2301 Female, age 85, both hemispheres 132.5
2188 Female, age 91, both hemispheres 106.8
2090 Male, age 80, both hemispheres 89.6
Dorsal cochlear nucleus
nTPM: 117.6
2058 Male, age 76, both hemispheres 141.3
2370 Male, age 61, both hemispheres 128.3
2187 Female, age 91, both hemispheres 110.0
2802 Male, age 74, right hemisphere 109.7
2378 Male, age 80, both hemispheres 98.8
Dorsal tegmental nucleus
nTPM: 113.2
2083 Male, age 80, both hemispheres 129.8
1936 Male, age 76, left hemisphere 128.2
2358 Male, age 61, both hemispheres 107.3
2326 Male, age 74, both hemispheres 87.7
Dorsolateral tegmental area
nTPM: 98.1
2141 Male, age 76, both hemispheres 137.3
2654 Male, age 80, both hemispheres 114.5
2751 Female, age 85, both hemispheres 107.1
2360 Male, age 74, both hemispheres 76.8
2337 Male, age 61, both hemispheres 55.0
Kolliker-Fuse nucleus
nTPM: 137.5
2793 Female, age 91, left hemisphere 163.4
2163 Male, age 80, both hemispheres 148.1
2315 Male, age 76, right hemisphere 101.0
Lateral lemniscal nuclei
nTPM: 220.1
2453 Male, age 74, right hemisphere 271.6
2169 Male, age 76, both hemispheres 244.2
2036 Male, age 80, both hemispheres 209.9
2320 Female, age 91, left hemisphere 194.0
2746 Female, age 85, left hemisphere 180.8
Lateral parabrachial nucleus
nTPM: 131.1
2139 Female, age 85, right hemisphere 199.8
2790 Male, age 61, both hemispheres 138.5
2013 Male, age 80, both hemispheres 123.1
2792 Male, age 76, both hemispheres 63.0
Lateral vestibular nucleus
nTPM: 135.3
2184 Male, age 76, both hemispheres 163.6
2311 Male, age 80, both hemispheres 107.1
Locus coeruleus
nTPM: 143.9
2123 Female, age 91, both hemispheres 162.5
2317 Female, age 72, unknown 153.7
2720 Male, age 74, both hemispheres 149.7
2162 Male, age 80, both hemispheres 146.2
1980 Male, age 76, both hemispheres 142.7
2014 Male, age 55, unknown 136.7
2788 Male, age 74, unknown 115.9
Medial olivary nucleus
nTPM: 63.4
2851 Male, age 80, both hemispheres 93.1
2138 Female, age 91, both hemispheres 63.7
1962 Male, age 76, both hemispheres 58.5
1943 Male, age 61, both hemispheres 38.2
Medial parabrachial nucleus
nTPM: 124.3
2156 Male, age 61, both hemispheres 148.7
2854 Male, age 80, both hemispheres 138.3
2786 Male, age 76, both hemispheres 121.5
2463 Female, age 85, right hemisphere 114.5
2170 Female, age 91, both hemispheres 98.6
Medial periolivary nuclei
nTPM: 210.8
2171 Female, age 85, both hemispheres 282.6
2063 Male, age 76, both hemispheres 277.4
2791 Male, age 74, right hemisphere 189.2
2458 Female, age 91, both hemispheres 174.9
2081 Male, age 80, both hemispheres 130.1
Motor facial nucleus
nTPM: 225.1
2062 Male, age 76, both hemispheres 303.6
2327 Male, age 80, both hemispheres 271.7
2795 Female, age 91, both hemispheres 252.8
2365 Male, age 74, right hemisphere 208.0
2697 Female, age 85, both hemispheres 178.4
2126 Male, age 61, both hemispheres 135.9
Motor trigeminal nucleus
nTPM: 169.2
2560 Male, age 74, both hemispheres 226.8
2079 Male, age 80, both hemispheres 204.2
2321 Female, age 91, both hemispheres 143.0
2335 Male, age 61, both hemispheres 140.9
2309 Male, age 76, both hemispheres 130.9
Nuclei of the trapezoid body
nTPM: 266.1
2735 Female, age 85, both hemispheres 316.8
2159 Male, age 61, both hemispheres 294.0
1983 Male, age 76, both hemispheres 272.9
2368 Female, age 91, both hemispheres 245.5
2166 Male, age 80, both hemispheres 201.4
Paramedian reticular nucleus
nTPM: 144.2
2050 Female, age 85, both hemispheres 191.9
2313 Male, age 61, both hemispheres 166.2
2057 Male, age 80, both hemispheres 137.5
2052 Male, age 76, both hemispheres 81.3
Pontine nuclei
nTPM: 213.3
2787 Female, age 85, both hemispheres 318.3
1968 Male, age 76, left hemisphere 265.8
2727 Male, age 61, right hemisphere 264.2
1863 Male, age 55, unknown 230.1
2109 Female, age 72, unknown 193.3
2115 Male, age 80, left hemisphere 162.7
2454 Male, age 74, left hemisphere 156.7
2319 Female, age 91, both hemispheres 115.5
Pontine raphe nucleus
nTPM: 186.7
2122 Female, age 85, midline 219.8
2853 Male, age 76, midline 153.6
Posteroventral cochlear nucleus
nTPM: 102.3
2752 Female, age 85, both hemispheres 172.1
2070 Male, age 76, both hemispheres 128.4
2371 Male, age 61, both hemispheres 119.0
2341 Male, age 80, both hemispheres 63.1
2135 Female, age 91, both hemispheres 29.2
Principal sensory trigeminal nucleus
nTPM: 204.8
2158 Male, age 61, both hemispheres 300.1
2008 Male, age 80, left hemisphere 223.1
2367 Female, age 91, left hemisphere 148.6
2324 Male, age 76, both hemispheres 147.6
Reticular pontine nucleus, caudal
nTPM: 191.0
2332 Male, age 80, right hemisphere 291.0
2092 Male, age 76, both hemispheres 188.9
2457 Female, age 91, both hemispheres 184.5
2559 Male, age 74, both hemispheres 99.7
Reticular pontine nucleus, oral
nTPM: 148.1
2361 Male, age 74, both hemispheres 182.1
2012 Female, age 85, both hemispheres 166.0
2366 Female, age 91, both hemispheres 143.7
2167 Male, age 76, both hemispheres 134.7
1939 Male, age 80, both hemispheres 114.3
Reticulotegmental nucleus
nTPM: 168.4
2325 Male, age 76, both hemispheres 194.2
2452 Male, age 74, both hemispheres 175.9
2333 Male, age 80, both hemispheres 162.8
2322 Female, age 91, both hemispheres 140.5
Spinal trigeminal nucleus, oral
nTPM: 146.3
2164 Male, age 80, both hemispheres 150.0
2737 Female, age 85, both hemispheres 147.1
1978 Male, age 76, both hemispheres 141.8
Subcoeruleus area
nTPM: 144.5
2089 Male, age 76, left hemisphere 196.1
1958 Male, age 80, both hemispheres 159.6
2323 Female, age 91, left hemisphere 151.7
2451 Male, age 74, both hemispheres 134.3
2369 Female, age 85, left hemisphere 80.7
Superior olive
nTPM: 200.8
2561 Female, age 91, both hemispheres 227.0
1875 Female, age 85, both hemispheres 218.0
2329 Male, age 80, right hemisphere 215.8
2020 Male, age 76, both hemispheres 178.9
2364 Male, age 74, right hemisphere 164.1
Superior vestibular nucleus
nTPM: 98.2
2061 Male, age 76, both hemispheres 115.7
2015 Male, age 80, both hemispheres 113.8
2383 Male, age 74, both hemispheres 65.1
Ventral periolivary nuclei
nTPM: 228.9
2130 Female, age 85, both hemispheres 272.9
2165 Male, age 80, both hemispheres 264.0
2794 Female, age 91, left hemisphere 222.3
2023 Male, age 76, both hemispheres 156.6
Ventrolateral tegmental area, A5 NE cell group
nTPM: 176.4
2449 Male, age 74, both hemispheres 244.1
2161 Male, age 80, both hemispheres 195.7
1959 Male, age 76, both hemispheres 193.9
2456 Female, age 91, both hemispheres 183.3
2840 Female, age 85, both hemispheres 138.3
2359 Male, age 61, both hemispheres 103.3

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 452.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 452.5
FF:10182-103D2 60 years, female 658.7
FF:10165-103B3 76 years, female 246.4
Pons
Scaled Tags Per Million: 444.6
FF:10033-101E6 18-54 years, mixed 444.6

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
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Average nTPM 407.5
Pig sample Sample description nTPM
Pons
nTPM: 407.5
Samples: 4

Max nTPM: 548.6
Min nTPM: 260.0
Sample A Female 548.6
Sample B Female 260.0
Sample C Male 360.3
Sample D Male 461.2

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 12.9
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 12.9
1004 Antisense, RP_Baylor_103022, Mouse strain C57BL/6J (56 days, male) 12.9

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.