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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:158.1 nTPM
HPA:158.1 nTPM
GTEx:163.0 nTPM
FANTOM5:47.8 Scaled Tags Per Million
Pig:339.6 nTPM
Mouse:529.7 nTPM
Allen mouse:14.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 158.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 119.6
2586 Male, age 75, left hemisphere 151.3
2219 Male, age 76, both hemispheres 136.0
1827 Male, age 72, unknown 135.9
2828 Female, age 72, unknown 130.3
2666 Male, age 74, left hemisphere 122.4
2411 Female, age 72, unknown 118.7
2019 Male, age 18, unknown 117.0
1870 Female, age 42, unknown 98.4
1833 Male, age 53, unknown 94.2
1830 Male, age 51, unknown 92.1
Dorsal raphe nucleus
nTPM: 113.7
2298 Female, age 72, unknown 133.7
2047 Male, age 72, unknown 128.7
1828 Male, age 53, unknown 111.0
2750 Male, age 76, both hemispheres 109.4
2016 Female, age 72, unknown 85.6
Inferior colliculus
nTPM: 119.5
1848 Female, age 42, unknown 124.8
2097 Female, age 72, unknown 124.2
2849 Male, age 72, unknown 118.3
1890 Male, age 53, unknown 110.6
Median raphe nucleus
nTPM: 133.8
2220 Male, age 76, midline 133.8
Pedunculopontine tegmental nucleus
nTPM: 115.6
1921 Female, age 85, both hemispheres 141.0
2334 Male, age 80, both hemispheres 110.2
2338 Male, age 61, both hemispheres 95.6
Periaquaductal grey, anterior
nTPM: 158.1
2502 Female, age 75, unknown 199.9
1795 Male, age 51, unknown 142.5
1947 Male, age 18, unknown 131.9
Periaquaductal grey, dorsal
nTPM: 109.3
1840 Male, age 53, unknown 120.2
2464 Female, age 72, unknown 115.8
1831 Male, age 72, unknown 108.3
2850 Male, age 76, both hemispheres 92.7
Periaquaductal grey, lateral
nTPM: 87.6
2053 Male, age 18, unknown 96.3
2140 Male, age 76, both hemispheres 94.3
2272 Male, age 74, both hemispheres 72.2
Pretectal area
nTPM: 125.7
2007 Male, age 72, unknown 170.7
1816 Male, age 51, unknown 162.2
1944 Female, age 72, unknown 160.3
1817 Female, age 42, unknown 143.8
2667 Female, age 75, unknown 131.1
1815 Male, age 53, unknown 121.0
2825 Male, age 18, unknown 109.8
2224 Female, age 72, unknown 108.2
2407 Male, age 75, both hemispheres 100.9
2316 Male, age 76, right hemisphere 100.2
2273 Male, age 74, both hemispheres 74.5
Red nucleus
nTPM: 91.0
2785 Male, age 18, unknown 114.3
2584 Male, age 75, left hemisphere 111.1
2588 Male, age 74, left hemisphere 97.8
2769 Male, age 72, unknown 93.3
1821 Female, age 72, unknown 92.4
1954 Female, age 42, unknown 91.9
2227 Male, age 72, unknown 90.9
2503 Female, age 72, unknown 84.7
2725 Female, age 75, unknown 81.8
2823 Male, age 76, right hemisphere 81.2
1865 Male, age 51, unknown 76.7
1904 Male, age 53, unknown 76.2
Substantia nigra
nTPM: 123.3
1941 Male, age 53, unknown 187.3
2665 Male, age 74, both hemispheres 167.8
1916 Female, age 42, unknown 149.3
1889 Female, age 72, unknown 136.6
1851 Male, age 51, unknown 132.3
2699 Male, age 18, unknown 98.8
2590 Female, age 75, unknown 95.4
2241 Male, age 72, unknown 94.9
2409 Female, age 72, unknown 85.8
2583 Male, age 75, right hemisphere 85.3
Superior colliculus
nTPM: 117.2
2664 Male, age 75, both hemispheres 164.8
2087 Female, age 72, unknown 143.7
1796 Male, age 53, unknown 129.4
2261 Male, age 18, unknown 128.1
1895 Male, age 76, right hemisphere 122.7
1839 Male, age 51, unknown 115.8
2668 Female, age 75, unknown 113.7
2587 Male, age 74, left hemisphere 103.3
1995 Male, age 72, unknown 75.5
1913 Female, age 42, unknown 75.3
Ventral tegmental area
nTPM: 123.6
2218 Male, age 76, both hemispheres 149.7
1915 Female, age 42, unknown 137.8
1942 Male, age 51, unknown 133.9
2410 Female, age 72, unknown 122.0
2021 Male, age 53, unknown 101.3
2223 Female, age 72, unknown 96.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 163.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 163.0
Samples: 139

Max nTPM: 722.4
Min nTPM: 34.9
Std nTPM: 97.2
Median nTPM: 142.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 722.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 509.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 403.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 359.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 342.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 317.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 307.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 304.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 298.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 290.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 282.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 277.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 274.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 272.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 268.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 267.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 267.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 261.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 260.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 257.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 256.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 254.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 251.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 250.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 248.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 246.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 245.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 245.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 238.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 233.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 231.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 229.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 224.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 220.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 217.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 213.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 210.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 206.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 205.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 204.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 202.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 202.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 200.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 199.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 199.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 199.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 195.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 191.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 191.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 190.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 190.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 185.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 183.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 182.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 175.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 175.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 174.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 172.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 170.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 162.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 161.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 159.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 159.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 155.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 152.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 149.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 147.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 144.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 143.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 142.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 141.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 141.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 140.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 140.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 134.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 132.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 129.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 128.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 126.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 122.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 120.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 119.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 118.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 117.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 114.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 114.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 110.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 108.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 106.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 105.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 104.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 104.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 103.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 103.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 103.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 102.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 102.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 101.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 101.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 96.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 95.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 95.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 95.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 94.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 93.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 91.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 89.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 87.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 86.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 85.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 85.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 83.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 82.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 80.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 76.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 74.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 73.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 73.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 72.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 71.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 71.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 70.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 69.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 67.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 66.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 64.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 58.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 58.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 55.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 53.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 50.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 47.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 47.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 46.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 43.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 41.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 39.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 39.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 34.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 47.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 47.8
FF:10158-103A5 76 years, female 47.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 339.6
Pig sample Sample description nTPM
Midbrain
nTPM: 270.4
Samples: 4

Max nTPM: 436.4
Min nTPM: 103.5
Sample A Female 103.5
Sample B Female 228.3
Sample C Male 436.4
Sample D Male 313.4
Periaqueductal gray
nTPM: 212.8
Samples: 3

Max nTPM: 269.4
Min nTPM: 170.9
Sample B Female 198.1
Sample C Male 269.4
Sample D Male 170.9
Substantia nigra
nTPM: 237.2
Samples: 4

Max nTPM: 406.3
Min nTPM: 74.7
Sample A Female 406.3
Sample B Female 150.3
Sample C Male 317.6
Sample D Male 74.7
Superior colliculi
nTPM: 339.6
Samples: 4

Max nTPM: 490.6
Min nTPM: 167.2
Sample A Female 406.8
Sample B Female 167.2
Sample C Male 490.6
Sample D Male 293.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 529.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 529.8
Samples: 4

Max nTPM: 616.5
Min nTPM: 459.9
Sample A Male 616.5
Sample B Male 503.7
Sample C Female 459.9
Sample D Female 538.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 14.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 14.8
1004 Antisense, RP_Baylor_103022, Mouse strain C57BL/6J (56 days, male) 14.8

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