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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

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No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:42.2 nTPM
HPA:42.2 nTPM
GTEx:32.5 nTPM
FANTOM5:136.8 Scaled Tags Per Million
Pig:26.8 nTPM
Mouse:43.1 nTPM
Allen mouse:0.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 42.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 40.9
2019 Male, age 18, unknown 43.8
2666 Male, age 74, left hemisphere 42.2
1830 Male, age 51, unknown 41.3
1870 Female, age 42, unknown 41.3
2411 Female, age 72, unknown 41.3
2586 Male, age 75, left hemisphere 41.3
2828 Female, age 72, unknown 41.0
1833 Male, age 53, unknown 40.6
1827 Male, age 72, unknown 39.3
2219 Male, age 76, both hemispheres 36.6
Dorsal raphe nucleus
nTPM: 39.3
2750 Male, age 76, both hemispheres 41.5
2016 Female, age 72, unknown 39.6
1828 Male, age 53, unknown 39.1
2047 Male, age 72, unknown 38.3
2298 Female, age 72, unknown 38.1
Inferior colliculus
nTPM: 39.3
1890 Male, age 53, unknown 40.2
2097 Female, age 72, unknown 40.1
1848 Female, age 42, unknown 38.9
2849 Male, age 72, unknown 38.0
Median raphe nucleus
nTPM: 39.6
2220 Male, age 76, midline 39.6
Pedunculopontine tegmental nucleus
nTPM: 40.1
2338 Male, age 61, both hemispheres 42.7
2334 Male, age 80, both hemispheres 39.5
1921 Female, age 85, both hemispheres 38.1
Periaquaductal grey, anterior
nTPM: 40.0
1947 Male, age 18, unknown 41.0
2502 Female, age 75, unknown 39.7
1795 Male, age 51, unknown 39.3
Periaquaductal grey, dorsal
nTPM: 39.3
2464 Female, age 72, unknown 41.1
1831 Male, age 72, unknown 39.4
2850 Male, age 76, both hemispheres 39.2
1840 Male, age 53, unknown 37.4
Periaquaductal grey, lateral
nTPM: 39.6
2140 Male, age 76, both hemispheres 40.9
2053 Male, age 18, unknown 39.0
2272 Male, age 74, both hemispheres 39.0
Pretectal area
nTPM: 40.3
2316 Male, age 76, right hemisphere 42.3
1815 Male, age 53, unknown 42.2
1817 Female, age 42, unknown 41.5
2007 Male, age 72, unknown 41.5
2407 Male, age 75, both hemispheres 40.8
1816 Male, age 51, unknown 40.3
1944 Female, age 72, unknown 40.0
2667 Female, age 75, unknown 39.1
2224 Female, age 72, unknown 38.7
2825 Male, age 18, unknown 38.4
2273 Male, age 74, both hemispheres 38.2
Red nucleus
nTPM: 42.2
1904 Male, age 53, unknown 43.9
1865 Male, age 51, unknown 43.8
2227 Male, age 72, unknown 43.2
2785 Male, age 18, unknown 42.5
2769 Male, age 72, unknown 42.2
2584 Male, age 75, left hemisphere 42.1
1954 Female, age 42, unknown 41.9
2503 Female, age 72, unknown 41.8
2823 Male, age 76, right hemisphere 41.7
1821 Female, age 72, unknown 41.6
2725 Female, age 75, unknown 41.2
2588 Male, age 74, left hemisphere 40.4
Substantia nigra
nTPM: 40.6
2583 Male, age 75, right hemisphere 42.5
2590 Female, age 75, unknown 41.7
2241 Male, age 72, unknown 41.5
2409 Female, age 72, unknown 41.5
1851 Male, age 51, unknown 40.7
2665 Male, age 74, both hemispheres 40.2
1941 Male, age 53, unknown 40.0
1889 Female, age 72, unknown 39.9
1916 Female, age 42, unknown 39.3
2699 Male, age 18, unknown 38.7
Superior colliculus
nTPM: 40.6
1913 Female, age 42, unknown 42.8
2668 Female, age 75, unknown 41.8
1995 Male, age 72, unknown 41.5
2261 Male, age 18, unknown 41.2
2087 Female, age 72, unknown 40.3
2587 Male, age 74, left hemisphere 40.3
1839 Male, age 51, unknown 39.6
1895 Male, age 76, right hemisphere 39.6
2664 Male, age 75, both hemispheres 39.5
1796 Male, age 53, unknown 39.3
Ventral tegmental area
nTPM: 40.1
2410 Female, age 72, unknown 40.9
2223 Female, age 72, unknown 40.5
2021 Male, age 53, unknown 40.1
2218 Male, age 76, both hemispheres 40.1
1942 Male, age 51, unknown 39.5
1915 Female, age 42, unknown 39.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 32.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 32.5
Samples: 139

Max nTPM: 55.9
Min nTPM: 15.3
Std nTPM: 8.0
Median nTPM: 31.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 55.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 55.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 51.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 51.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 50.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 49.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 49.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 48.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 47.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 47.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 45.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 43.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 43.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 43.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 42.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 41.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 41.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 41.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 41.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 40.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 40.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 40.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 40.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 39.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 39.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 39.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 39.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 39.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 39.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 39.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 38.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 38.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 38.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 37.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 37.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 37.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 37.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 37.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 37.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 37.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 36.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 36.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 36.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 36.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 36.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 36.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 36.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 35.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 35.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 35.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 35.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 34.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 34.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 33.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 33.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 33.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 33.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 33.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 32.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 32.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 32.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 31.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 31.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 31.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 31.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 31.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 31.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 31.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 31.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 31.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 31.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 31.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 31.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 30.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 30.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 30.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 30.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 30.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 30.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 29.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 29.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 29.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 29.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 29.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 29.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 29.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 29.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 29.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 29.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 29.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 29.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 28.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 28.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 28.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 28.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 28.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 28.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 27.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 27.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 27.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 27.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 27.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 27.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 27.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 27.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 26.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 26.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 26.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 26.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 25.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 25.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 25.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 25.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 25.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 25.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 24.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 24.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 24.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 24.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 24.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 24.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 23.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 23.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 23.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 23.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 23.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 22.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 22.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 22.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 22.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 21.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 20.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 20.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 20.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 20.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 18.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 18.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 18.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 15.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 136.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 136.8
FF:10158-103A5 76 years, female 136.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 26.8
Pig sample Sample description nTPM
Midbrain
nTPM: 24.9
Samples: 4

Max nTPM: 33.5
Min nTPM: 19.3
Sample A Female 33.5
Sample B Female 25.7
Sample C Male 21.0
Sample D Male 19.3
Periaqueductal gray
nTPM: 22.3
Samples: 3

Max nTPM: 24.0
Min nTPM: 19.4
Sample B Female 23.5
Sample C Male 24.0
Sample D Male 19.4
Substantia nigra
nTPM: 26.8
Samples: 4

Max nTPM: 28.6
Min nTPM: 24.5
Sample A Female 27.9
Sample B Female 26.1
Sample C Male 24.5
Sample D Male 28.6
Superior colliculi
nTPM: 25.6
Samples: 4

Max nTPM: 29.6
Min nTPM: 21.3
Sample A Female 29.6
Sample B Female 21.3
Sample C Male 25.8
Sample D Male 25.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 43.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 43.1
Samples: 4

Max nTPM: 45.3
Min nTPM: 38.6
Sample A Male 44.6
Sample B Male 38.6
Sample C Female 43.9
Sample D Female 45.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.4
69116877 Antisense, RP_050321_01_D01, Mouse strain C57BL/6J (56 days, male) 0.4

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