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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:49.6 nTPM
HPA:49.6 nTPM
GTEx:61.6 nTPM
FANTOM5:268.0 Scaled Tags Per Million
Pig:186.4 nTPM
Mouse:163.4 nTPM
Allen mouse:16.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 49.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 20.6
2019 Male, age 18, unknown 66.4
2219 Male, age 76, both hemispheres 45.6
2828 Female, age 72, unknown 31.1
1827 Male, age 72, unknown 26.9
2586 Male, age 75, left hemisphere 21.7
2666 Male, age 74, left hemisphere 7.5
2411 Female, age 72, unknown 7.3
1830 Male, age 51, unknown 0.0
1833 Male, age 53, unknown 0.0
1870 Female, age 42, unknown 0.0
Dorsal raphe nucleus
nTPM: 27.1
2298 Female, age 72, unknown 49.8
1828 Male, age 53, unknown 40.2
2047 Male, age 72, unknown 37.0
2016 Female, age 72, unknown 8.7
2750 Male, age 76, both hemispheres 0.0
Inferior colliculus
nTPM: 28.7
2097 Female, age 72, unknown 40.2
1848 Female, age 42, unknown 36.5
1890 Male, age 53, unknown 19.7
2849 Male, age 72, unknown 18.4
Median raphe nucleus
nTPM: 1.7
2220 Male, age 76, midline 1.7
Pedunculopontine tegmental nucleus
nTPM: 8.1
1921 Female, age 85, both hemispheres 20.5
2334 Male, age 80, both hemispheres 3.9
2338 Male, age 61, both hemispheres 0.0
Periaquaductal grey, anterior
nTPM: 37.0
1795 Male, age 51, unknown 43.0
2502 Female, age 75, unknown 41.8
1947 Male, age 18, unknown 26.2
Periaquaductal grey, dorsal
nTPM: 12.4
1840 Male, age 53, unknown 23.1
2464 Female, age 72, unknown 16.4
1831 Male, age 72, unknown 9.6
2850 Male, age 76, both hemispheres 0.4
Periaquaductal grey, lateral
nTPM: 10.3
2272 Male, age 74, both hemispheres 28.4
2140 Male, age 76, both hemispheres 2.4
2053 Male, age 18, unknown 0.0
Pretectal area
nTPM: 45.9
1816 Male, age 51, unknown 92.0
1944 Female, age 72, unknown 83.1
2007 Male, age 72, unknown 80.7
2273 Male, age 74, both hemispheres 66.2
1817 Female, age 42, unknown 64.0
2667 Female, age 75, unknown 35.7
1815 Male, age 53, unknown 30.0
2224 Female, age 72, unknown 28.4
2407 Male, age 75, both hemispheres 22.5
2316 Male, age 76, right hemisphere 1.8
2825 Male, age 18, unknown 0.0
Red nucleus
nTPM: 7.4
2785 Male, age 18, unknown 55.3
2725 Female, age 75, unknown 24.1
2503 Female, age 72, unknown 6.3
2584 Male, age 75, left hemisphere 3.1
1821 Female, age 72, unknown 0.0
1865 Male, age 51, unknown 0.0
1904 Male, age 53, unknown 0.0
1954 Female, age 42, unknown 0.0
2227 Male, age 72, unknown 0.0
2588 Male, age 74, left hemisphere 0.0
2769 Male, age 72, unknown 0.0
2823 Male, age 76, right hemisphere 0.0
Substantia nigra
nTPM: 49.6
1941 Male, age 53, unknown 134.7
1916 Female, age 42, unknown 108.3
1851 Male, age 51, unknown 55.5
1889 Female, age 72, unknown 47.5
2665 Male, age 74, both hemispheres 44.7
2590 Female, age 75, unknown 34.8
2241 Male, age 72, unknown 28.7
2583 Male, age 75, right hemisphere 25.3
2699 Male, age 18, unknown 16.5
2409 Female, age 72, unknown 0.0
Superior colliculus
nTPM: 27.7
2664 Male, age 75, both hemispheres 61.4
2087 Female, age 72, unknown 59.9
1796 Male, age 53, unknown 37.6
2587 Male, age 74, left hemisphere 35.6
1895 Male, age 76, right hemisphere 33.2
2261 Male, age 18, unknown 23.8
2668 Female, age 75, unknown 9.6
1839 Male, age 51, unknown 9.5
1995 Male, age 72, unknown 6.5
1913 Female, age 42, unknown 0.0
Ventral tegmental area
nTPM: 27.9
1915 Female, age 42, unknown 55.5
2410 Female, age 72, unknown 39.7
2218 Male, age 76, both hemispheres 31.5
1942 Male, age 51, unknown 30.2
2021 Male, age 53, unknown 5.4
2223 Female, age 72, unknown 4.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 61.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 61.6
Samples: 139

Max nTPM: 287.3
Min nTPM: 23.6
Std nTPM: 31.4
Median nTPM: 53.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 287.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 203.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 137.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 130.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 123.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 117.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 116.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 112.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 103.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 102.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 101.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 100.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 95.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 94.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 92.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 91.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 90.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 88.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 86.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 83.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 81.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 80.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 79.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 77.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 76.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 76.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 76.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 76.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 75.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 73.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 73.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 68.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 66.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 66.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 66.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 66.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 65.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 65.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 64.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 64.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 63.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 63.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 63.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 62.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 62.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 61.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 61.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 61.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 61.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 61.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 60.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 59.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 59.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 59.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 59.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 59.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 58.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 58.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 56.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 56.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 56.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 56.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 56.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 55.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 55.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 55.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 54.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 54.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 54.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 53.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 53.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 53.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 53.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 53.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 53.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 52.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 51.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 51.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 51.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 51.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 51.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 51.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 50.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 50.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 50.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 49.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 48.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 48.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 48.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 47.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 47.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 47.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 47.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 46.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 46.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 46.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 46.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 45.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 45.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 45.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 45.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 45.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 45.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 44.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 44.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 44.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 44.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 44.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 44.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 44.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 43.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 43.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 42.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 42.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 41.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 41.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 41.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 41.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 40.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 40.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 40.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 40.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 39.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 38.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 37.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 35.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 35.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 35.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 35.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 35.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 34.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 32.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 32.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 31.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 31.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 30.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 29.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 27.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 23.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 268.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 268.0
FF:10158-103A5 76 years, female 268.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 186.4
Pig sample Sample description nTPM
Midbrain
nTPM: 163.2
Samples: 4

Max nTPM: 270.3
Min nTPM: 91.2
Sample A Female 91.2
Sample B Female 110.3
Sample C Male 270.3
Sample D Male 180.9
Periaqueductal gray
nTPM: 111.6
Samples: 3

Max nTPM: 139.2
Min nTPM: 87.4
Sample B Female 108.1
Sample C Male 139.2
Sample D Male 87.4
Substantia nigra
nTPM: 153.1
Samples: 4

Max nTPM: 203.6
Min nTPM: 79.7
Sample A Female 203.6
Sample B Female 125.8
Sample C Male 203.4
Sample D Male 79.7
Superior colliculi
nTPM: 186.4
Samples: 4

Max nTPM: 235.9
Min nTPM: 147.9
Sample A Female 182.6
Sample B Female 147.9
Sample C Male 235.9
Sample D Male 179.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 163.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 163.4
Samples: 4

Max nTPM: 184.4
Min nTPM: 133.9
Sample A Male 133.9
Sample B Male 170.1
Sample C Female 184.4
Sample D Female 165.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 16.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 16.4
70596059 Antisense, RP_050628_04_A03, Mouse strain C57BL/6J (56 days, male) 18.9
69885690 Antisense, RP_050512_03_C04, Mouse strain C57BL/6J (56 days, male) 13.9

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